Human metapneumovirus in Singapore : epidemiology, fusion-attachment protein interaction and virus-like particle assembly by Loo, Liat Hui

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DRD-UNet, a UNet-like architecture for multi-class breast cancer semantic segmentation by Ortega-Ruíz, Mauricio Alberto, Karabağ, Cefa, Roman-Rangel, Edgar, Reyes-Aldasoro, Constantino Carlos

“…This paper describes a UNet-like deep learning architecture called DRD-UNet, which adds a novel processing block called DRD (Dilation, Residual, and Dense block) to a UNet architecture. …”
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Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines by Sherry, L, Bahar, MW, Porta, C, Fox, H, Grehan, K, Nasta, V, Duyvesteyn, HME, De Colibus, L, Marsian, J, Murdoch, I, Ponndorf, D, Kim, S, Shah, S, Carlyle, S, Swanson, JJ, Matthews, S, Nicol, C, Lomonossoff, GP, Macadam, AJ, Fry, EE, Stuart, DI, Stonehouse, NJ, Rowlands, DJ

“…Continued use of these vaccines, however, threatens ultimate disease eradication and achievement of a polio-free world. Virus-like particles (VLPs) that lack a viral genome represent a safer potential vaccine, although they require particle stabilization. …”

Bacteriocin-like peptides encoded by a horizontally acquired island mediate Neisseria gonorrhoeae autolysis by Poncin, K, McKeand, SA, Lavender, H, Kurzyp, K, Harrison, OB, Roberti, A, Melia, C, Johnson, E, Maiden, MCJ, Greaves, DR, Exley, R, Tang, CM

“…The nap island in the gonococcus encodes 3 cationic, bacteriocin-like peptides which have no detectable antimicrobial activity. …”

Distinct movement disorders in contactin-associated-protein-like-2 antibody-associated autoimmune encephalitis by Gövert, F, Abrante, L, Becktepe, J, Balint, B, Ganos, C, Hofstadt-van Oy, U, Krogias, C, Varley, J, Irani, SR, Paneva, S, Titulaer, MJ, de Vries, JM, Boon, AJW, Schreurs, MWJ, Joubert, B, Honnorat, J, Vogrig, A, Ariño, H, Sabater, L, Dalmau, J, Scotton, S, Jacob, S, Melzer, N, Bien, CG, Geis, C, Lewerenz, J, Prüss, H, Wandinger, K-P, Deuschl, G, Leypoldt, F

“…In the elderly, anti-LGI1 and contactin associated protein like 2 (CASPR2) antibody-associated diseases compose a relevant fraction of autoimmune encephalitis. …”

Heterogeneity in definitions of surgical site infection after cranial surgery limits the validity of research findings in neurosurgery: a systematic review by Majidi, N, Sivakumar, A, Vogt, A, Ranganathan, S, Ashkan, K, Price, SJ, Lee, KS

“…This heterogeneity has hindered the ability to draw conclusions about the effects of interventions, with only 4.0% of authors accounting for this in their findings. It is important to be cautious when reviewing studies that report SSI-CRAN outcomes without acknowledging this heterogeneity, as the validity of their reported evidence may be limited. …”

Using knowledge translation to support the use of evaluation findings: A case study of the linda mama free maternity program in Kenya by Guleid, FH, Orangi, S, Kairu, A, Arwa, B, Keru, J, Musuva, A, Vilcu, I, Pattnaik, A, Ravishankar, N, Barasa, E

“…Using program evaluation findings is crucial in improving health programs and realising the program’s benefits. …”

Improving the well-being outcomes via decent work and job engagement: a findings from Persons With Disabilities (PWDs) in Malaysia by Norizan Baba Rahim, Rasidah Arshad, Zulnaidi Yaacob

“…Using purposive sampling technique which involved 143 PWDs in Malaysia via SurveyMonkey, the measurement items were adopted from past research with acceptable reliability, and the hypothesis were tested via Partial Least Squares (PLS) 2.0. The findings revealed that decent work was related to well-being outcomes. …”
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Single cell hydrodynamic stretching and microsieve filtration reveal genetic, phenotypic and treatment-related links to cellular deformability by Li, Fenfang, Cima, Igor, Vo, Jess Honganh, Tan, Min-Han, Ohl, Claus-Dieter

“…In another model, the breast epithelial cells MCF10A with deletion of the TP53 gene are also significantly more deformable compared to their isogenic wildtype counterpart, indicating a potential genetic link to cellular deformability. We also find that the drug docetaxel leads to an increase in the size of A549 lung cancer cells. …”
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Wireless channel modeling and spectrum monitoring for interference mitigation and link reliability insurance for existing and future CBTC systems by Kalyankar Shravan Kumar

“…The statistics of the clustered data are analyzed to understand the characteristics of radio signals from different access points, and the findings of this technique are presented. The study shows that the proposed approach can be used in real-time monitoring of access points (APs) and help the MRT operators identify the faulty APs without any in-field tests. …”
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Linking personal control and environmental distraction with creative outcome through satisfaction action with work environment and social interaction / by Sanaz Ahmadpoor Samani, 1984-, author 605358

Highly reliable carbon nanotube-based composite fibers cross-linked by a 3D polymer network by Sun, Gengzhi, Zheng, Lianxi, Zhan, Zhaoyao, Jiang, Chunbo, Hansen, Reinack V., Khor, Yengpeng, Pang, John Hock Lye

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Robust perfluorophenylboronic acid-catalyzed stereoselective synthesis of 2,3-unsaturated O-, C-, N- and S-linked glycosides by Tatina, Madhu Babu, Xia, Mengxin, Rao, Peilin, Judeh, Zaher M. A.

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Linking short-term to long-term convergent tectonics using geodetic observations, geological constraints and numerical simulations by Mallick, Rishav

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High-density three-dimensional network of covalently linked nitric oxide donors to achieve antibacterial and antibiofilm surfaces by Wang, Liping, Hou, Zheng, Pranantyo, Dicky, Kang, En-Tang, Chan-Park, Mary B.

“…We have invented a novel pretreatment chemistry for device surfaces to produce a high-density three-dimensional (3-D) network of covalently linked S-nitrosothiol (RSNO), which is a nitric oxide (NO) donor. …”
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Sig2GRN : a software tool linking signaling pathway with gene regulatory network for dynamic simulation by Zhang, Fan, Liu, Runsheng, Zheng, Jie

“…Background: Linking computational models of signaling pathways to predicted cellular responses such as gene expression regulation is a major challenge in computational systems biology. …”
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Linking microstructure and local mechanical properties in SiC-SiC fiber composite using micromechanical testing by Zayachuk, Y, Karamched, P, Deck, C, Hosemann, P, Armstrong, DEJ

Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration by James, Rachel E., Schalks, Renee, Browne, Eleanor, Eleftheriadou, Ioanna, Munoz, Carmen Picon, Mazarakis, Nicholas D., Reynolds, Richard

“…Here we tested the hypothesis that persistent production of these cytokines in the meningeal compartment and diffusion into underlying GM can drive chronic MS-like GM pathology. Lentiviral transfer vectors were injected into the sagittal sulcus of DA rats to deliver continuous expression of TNF + IFNγ transgenes in the meninges and the resulting neuropathology analysed after 1 and 2 months. …”
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Local rainfall is more likely than distant thunderstorms to affect movement behaviour in Northern Kenyan elephants by Mulder, T, Mortimer, B, Ferwerda, J, Vollrath, F

“…We conclude that climate change makes a strong case for studying elephant behaviours in response to environmental cues during the day and night, especially in dry-land study sites like Northern Kenya.…”

Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer by Alsaiari, Shahad K., Nadeef, Seba, Daristotle, John L., Rothwell, William, Du, Bujie, Garcia, Johnny, Zhang, Linzixuan, Sarmadi, Morteza, Forster, Timothy A., Menon, Nandita, Lin, Stacey Qiaohui, Tostanoski, Lisa H., Hachmann, Nicole, Wang, Erika Yan, Ventura, John D., Barouch, Dan H., Langer, Robert, Jaklenec, Ana

“…In this work, we report the Toll-like receptor agonist activity of a nanoscale adjuvant zeolitic imidazolate framework–8 (ZIF-8). …”
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