Early Prediction of Skin Viability Using Visible Diffuse Reflectance Spectroscopy and Autofluorescence Spectroscopy by Zhu, Caigang, Chen, Shuo, Chui, Christopher Hoe-Kong, Tan, Bien-Keem, Liu, Quan

“…Meanwhile, several physiologically relevant parameters including hemoglobin oxygenation, total hemoglobin concentration, and redox ratio indicators estimated from diffuse reflectance and autofluorescence spectra show distinctively different trends over time for nonviable and viable skin. Conclusions: These findings will be helpful to clinicians for making a precise judgment on flap viability. …”
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Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and is Activated by PPARβ/δ Deficiency by Zarei, Mohammad, Barroso, Emma, Leiva, Rosana, Barniol-Xicota, Marta, Pujol, Eugènia, Escolano, Carmen, Vázquez, Santiago, Palomer, Xavier, Pardo, Virginia, González-Rodríguez, Águeda, Valverde, Ángela M., Quesada-López, Tania, Villarroya, Francesc, Wahli, Walter, Vázquez-Carrera, Manuel

“…Moreover, pharmacological activation of HRI increased Fgf21 expression and reduced lipid-induced hepatic steatosis and glucose intolerance and these effects were not observed in Fgf21-null mice. Overall, these findings suggest that HRI is a potential target for regulating hepatic FGF21 levels.…”
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Ethnic differences in knowledge, attitudes, and practices related to dietary salt intake and association with hypertension in Malaysia: a multi-centre cross-sectional study by Chia, Yook Chin, Ching, Siew Mooi, Chew, Ming Tsuey, Devaraj, Navin Kumar, Oui, Jethro Ee Keat, Lim, Hooi Min, Chew, Bee Nah, Mohamed, Mohazmi, Ooi, Pei Boon, Cheng, Maong Hui, Beh, Hooi Chin, Chung, Felicia Fei-Lei

“…Those who were unaware of the difference between salt and sodium and who reported not reading salt labels had higher odds of having elevated blood pressure. These findings demonstrate that while there is a suboptimal translation of salt knowledge into practice in Malaysia, with significant differences in KAP observed between ethnic groups, the potential of improving health outcomes by improving the clarity and awareness of salt labels is substantial. …”

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... by Ferrari, AJ, Santomauro, DF, Aali, A, Lacey, BWH, Rodriguez, JAB

“…A global epidemiological transition remains underway. Our findings suggest that prioritising non-communicable disease prevention and treatment policies, as well as strengthening health systems, continues to be crucially important. …”

Generation of lentiviral-mediated shRNA vectors to inhibit the expression of caspase-1 and Pycard/ASC in dendritic cells. by Tan, Bee Kim.

“…Collectively, we have generated an efficient lentiviral vector-mediated shRNA silencing system in primary cell lines which could provide an insight to into the biological mechanisms involved in inflammasome activation.…”
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Discovery of exosomes as gastric cancer biomarkers from conditioned cell culture media. by Low, Su Jun.

“…We isolated exosomes by concentrating 100ml of conditioned cell culture media from 3 gastric cancer cell lines AGS, NCIN87 and IM95, and subjected them to ultracentrifugation. …”
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Effects of hemodynamic shear stress on circulating breast cancer cells by Khairunisa Liyana Abdul Malek

“…In this project, three lines of metastatic breast cancer cells, 231-C3, 231-M1 and 231-M1A were circulated in a microfluidic model mimicking the blood circulatory system over four different time periods: 2 hours, 4 hours, 9 hours and 18 hours while being exposed to three different hemodynamic shear stress at values of 15 dyn/cm2, 30 dyn/cm2 and 45 dyn/cm2. …”
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Laplacian Regularized Subspace Learning for interactive image re-ranking by Zhang, Lining., Wang, Lipo., Lin, Weisi.

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Motive and malice prepensed by Getzler, J

“…I would open the notes arriving from Magdalen with great anticipation, looking forward to discussing the contents with David, and knowing that his lines would set me off into fresh discoveries in libraries and archives for a good few weeks or months. …”

Statistical theory of the broadband two-plasmon decay instability by Rusko, RT, Bingham, R, Silva, LO, Harper, M, Aboushelbaya, R, Myatt, JF, Norreys, PA

“…The instability-quenching properties of a spectrum of discrete lines spread over some bandwidth have also been studied. …”

Paper or Tablet? The Impact of Digital Tools on Sketching During Engineering Design Concept Generation by Das, Madhurima, Huang, May, Yang, Maria

“…This is especially important as tablets can automatically smooth lines and help perfect sketch features, but these features may also take longer to use and may result in fewer sketches produced.…”
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Selective targeting of MYC mRNA by stabilized antisense oligonucleotides by Gill, Taylor, Wang, Haichuan, Bandaru, Raj, Lawlor, Matthew, Lu, Chenyue, Nieman, Linda T, Tao, Junyan, Zhang, Yixian, Anderson, Daniel G, Ting, David T, Chen, Xin, Bradner, James E, Ott, Christopher J

“…MYCASO treatment of cancer cell lines leads to significant inhibition of cellular proliferation while specifically perturbing MYC-driven gene expression signatures. …”
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Unsupervised Learning for Generative Scene Editing and Motion by Fang, David S.

“…In this thesis, we propose two distinct lines of unsupervised learning work with generative applications: 1) BlobGSN and 2) optical flow estimation and flow generation with diffusion models. …”
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A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system by Shen, Yunbing, Jiang, Long, Iyer, Vaishnavi Srinivasan, Raposo, Bruno, Dubnovitsky, Anatoly, Boddul, Sanjaykumar V., Kasza, Zsolt, Wermeling, Fredrik

“…Here, we present a rapid and universal experimental approach to functionally analyze a CRISPR-targeted cell population that does not involve generating clonal lines. As a simple readout, we leverage the CRISPR-induced genetic heterogeneity and use sequencing to identify how different genotypes are enriched or depleted in relation to the studied cellular behavior or phenotype. …”
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Label-free assessment of differentiation efficiency in iPSC-derived spinal cord progenitor cells via Magnetic Resonance Relaxometry (MRR) by Tan, Jerome Zu Yao, Chen, Jiahui, Roxby, Daniel, Chooi, Wai Hon, Nguyen, Tan Dai, Ng, Shi-Yan, Chew, Sing Yian, Han, Jongyoon

“…In this study, human iPSCs derived from Cord Lining Endothelial cells were differentiated into Spinal-cord Progenitor Cells (SCPCs) through a 10-day process. …”
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Flexible integrated sensor with asymmetric structure for simultaneously 3D tactile and thermal sensing by Wang, Yongqing, Sun, Kun, Zhang, Qisheng, Yu, Samson Shenglong, Han, Boon Siew, Wang, Jianpeng, Zhao, Mingyan, Meng, Xianglin, Chen, Sicheng, Zheng, Yuanjin

“…The resistive thermal sensors are fabricated with serpentine lines and possess stable heat-sensing performance (165 mV/°C) under shape deformation conditions. …”
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Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin by Peng, Minhua, Watanabe, Satoru, Chan, Kitti Wing Ki, He, Qiuyan, Zhao, Ya, Zhang, Zhongde, Lai, Xiaoping, Luo, Dahai, Vasudevan, Subhash G., Li, Geng

“…In addition, ADE-mediated dengue virus infection of human cell lines and primary PBMCs was inhibited. In a time-of-drug-addition study, luteolin was found to reduce infectious virus particle formation, but not viral RNA synthesis, in Huh-7 cells. …”
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Mythical heroines : the appropriation of myth in reconstructing female identities in ethnic American literature by Goh, I-Mei.

“…The three literary texts being investigated along these lines are Maxine Hong Kingston’s The Woman Warrior, Bharati Mukherjee’s Jasmine and Toni Morrison’s Beloved. …”
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Functional analysis of root-preferential oil palm metallothionein promoter in tobacco by Masura, Subhi Siti, Shaharuddin, Noor Azmi, Masani, Mat Yunus Abdul, Chan, Kuang-Lim, Low, Eng-Ti Leslie, Chan, Pek-Lan, Rahmah, Abdul Rahman Siti, Amiruddin, Nadzirah, Abdullah, Mohd Puad, Azzeme, Azzreena Mohamad, Parveez, Ghulam Kadir Ahmad, Abd Rasid, Omar

“…Stable functional characterisation of tobacco transgenic lines using the T1 generation showed that a deletion construct, designated as RSP-2D (1107 bp), directed strong GUS expression at all stages of root development, particularly in mature roots. …”

Determinants of Expatriate Manager Failures in the International Assignment by Mansor, Mohd Fitri, Abd Hamid, Nurzawani, Kamil, Syahida, Abu, Noor Hidayah

“…The international assignment requires an organization send their staff abroad for high potential career development, to coordinate global lines of business, transfer the organization knowledge in abroad, expand into new markets worldwide and also manage an international subsidiary. …”
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