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    Understanding the disease mechanisms of cerebellar ataxia through induced pluripotent stem cell models by Wong, M

    Published 2018
    “…Notably, the dendritic development and survival of human SCA14 Purkinje cells were significantly compromised in long-term culture. CRISPR/Cas9-mediated genome editing was also employed to correct the mutations and produce isogenic controls of SCA14 iPSCs. …”
    Thesis
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