Development of immune-modulatory RNAS to regulate RIG-I-like receptors mediated antiviral immune response for therapy and vaccination by Yong, Hui Yee

“…Next, the encapsulation of ImmRNAs into virus-like particles (VLP) was carried out. The coat protein for two different RNA bacteriophage, MS2 and Q beta were cloned and recombinantly expressed in E.coli. …”
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Template-free formation of uniform urchin-like α-FeOOH hollow spheres with superior capability for water treatment by Wang, Bao, Wu, Hao Bin, Yu, Le, Xu, Rong, Lim, Teik-Thye, Lou, David Xiong Wen

“…Uniform urchin-like α-FeOOH hollow spheres assembled from nanoneedles have been synthesized via a facile and green one-pot method. …”
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CuOx nanotubes via an unusual complexation induced block copolymer-like self-assembly of poly(acrylic acid) by Liang, Yen Nan, Hu, Jinhua, Tam, Michael Kam Chiu, Hu, Xiao

“…Such a unique copolymer-like self-assembly behaviour of the PAA–Cu2+ complex manifests within a specific window of [Cu2+] : [COOH]0 ratio around the binding limit. …”
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Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes by Low, Jianrong L., Gehring, Adam J., Kranz, David M., Grotenbreg, Gijsbert M., Yau, Yin Hoe, Shochat, Susana Geifman, Bertoletti, Antonio, Naidoo, Anneta, Yeo, Gladys, Ho, Zi Zong

“…In line with this, we report the construction of a soluble tetrameric form of an αβ T cell receptor (TCR) specific for the HBV epitope Env183–191 restricted by HLA-A*02:01, and compare its avidity and fine-specificity with a TCR-like monoclonal antibody generated against the same HLA target. …”
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Like the sea: living communityship as a form of participatory leadership within the creativity for learning in HE (#creativeHE) community by Nerantzi, Chrissi, Gillaspy, Emma, Sinfield, Sandra, Karatsiori, Marianthi, Burns, Tom, Hunter, Anna, Seat, Hannah, Tasler, Nathalie

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Immunotherapy-resistant neuropathic pain and fatigue predict quality-of-life in contactin-associated protein-like 2 antibody disease by Ceronie, B, Strippel, C, Uy, C, Paneva, S, Makuch, M, Soleimani, B, Turaga, S, Binks, S, Ramanathan, S, Michael, S, Varley, J, Easton, A, Themistocleous, A, John Dawes, Bennett, DL, Irani, A, Handel, AE, Irani, SR

“…The long-term clinical outcomes and associated prognostic factors in contactin-associated protein-like 2 (CASPR2)-antibody diseases are unknown. A total of 75 participants with CASPR2 antibodies were longitudinally assessed for disability, quality-of-life, and chronic pain. …”

Nationwide spatial epidemiological dataset of over 100,000 influenza-like illness notifications in Iran by county (2015–2019) by Sedghian, A, MohammadEbrahimi, S, Sartorius, B, Kiani, B

“…Objectives: This data note documents influenza-like illness (ILI) notifications in Iran by county from 2015 to 2019 as a pre-COVID-19 dataset, providing individual and spatial data for further comprehensive spatiotemporal analysis. …”

Development of superhydrophobic ceramic membrane decorated with flake-like structure by two-step synthesis for seawater desalination by membrane distillation by Omar, Najib Meftah Almukhtar, Othman, Mohd. Hafiz Dzarfan, Tai, Zhong Sheng, Puteh, Mohd. Hafiz, Wong, Keng Yinn, Tan, Huiyi, Tonni Agustiono Kurniawan, Tonni Agustiono Kurniawan, Ooi, Boon Seng, Nomura, Mikihiro, Iwamoto, Yuji

“…Significant findings: The results revealed that the MK-SS/4 h HFM, characterized by its flake-like structure, exhibited optimal superhydrophobic behavior. …”

Deactivation of the parvalbumin-positive interneurons in the hippocampus after fear-like behaviour following electrical stimulation of the dorsolateral periaqueductal gray of rats by Temel, Yasin., Blokland, Arjan., Lim, Lee Wei.

“…In conclusion, our findings indicate that the inhibition of this subpopulation of hippocampal parvalbumin-positive interneurons induced a long lasting anxiety- or fear-like behaviour.…”
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The political economy of oil and economic diversification: a neglected research field Robert Mabro would certainly like us to revive by Aissaoui, A

Sampling Signals With a Finite Rate of Innovation on the Sphere by Deslauriers-Gauthier, Samuel, Marziliano, Pina

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Modern Game Testing : Learn how to test games like a pro, optimize testing effort, and skyrocket your QA career / by Finska, Nikolina, author 656259

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Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer by Alsaiari, Shahad K., Nadeef, Seba, Daristotle, John L., Rothwell, William, Du, Bujie, Garcia, Johnny, Zhang, Linzixuan, Sarmadi, Morteza, Forster, Timothy A., Menon, Nandita, Lin, Stacey Qiaohui, Tostanoski, Lisa H., Hachmann, Nicole, Wang, Erika Yan, Ventura, John D., Barouch, Dan H., Langer, Robert, Jaklenec, Ana

“…In this work, we report the Toll-like receptor agonist activity of a nanoscale adjuvant zeolitic imidazolate framework–8 (ZIF-8). …”
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Robust microhoneycomb-like nanofibrous aerogels derived from cellulose and lignin as highly efficient, low-resistant and anti-clogging air filters by Ma, Daphne Xiu Yun, Zeng, Zhihui, Wang, Zhe, Xu, Lulu, Zhang, Youfang, Ang, Jia Ming, Wan, Man Pun, Ng, Bing Feng, Lu, Xuehong

“…In this article, we report highly porous yet robust microhoneycomb-like nanofibrous aerogels (NFAs) with porous cell walls and hierarchical porous structures, and their potential as durable high-performance air filters. …”
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Testosterone, sex hormone-binding globulin, insulin-like growth factor-1 and endometrial cancer risk: observational and Mendelian randomization analyses by Mullee, A, Dimou, N, Allen, N, O'Mara, T, Gunter, MJ, Murphy, N

“…<p><strong>Background</strong></p> Dysregulation of endocrine pathways related to steroid and growth hormones may modify endometrial cancer risk; however, prospective data on testosterone, sex hormone-binding globulin (SHBG) and insulin-like growth factor (IGF)−1 are limited. To elucidate the role of these hormones in endometrial cancer risk we conducted complementary observational and Mendelian randomization (MR) analyses. …”

Oral and topical administration of a geranyl acetophenone attenuates DNCB-induced atopic dermatitis-like skin lesions in BALB/c mice by Mohd Kasim, Vivi Nur Khalieda, Lee, Yu Zhao, Bakrin, Ikmal Hisyam, Hussain, Mohd Khairi, Israf, Daud Ahmad, Shaari, Khozirah, Tan, Ji Wei, Lee, Ming Tatt, Tham, Chau Ling

“…Using a mouse DNCB-induced AD-like skin lesions model, this study evaluated the potential therapeutic utility of tHGA as an oral and topical treatment for AD. …”
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Nanofiltration-like forward osmosis membranes with graphene oxide modified polymer-blended subtrate for aerobically-treated palm oil mill effluent treatment / by Wan Nur Ain Shuhada Abdullah, 1994-, author 655804, Lau, Woei Jye, 1983-, supervisor 483710, Farhana Aziz, supervisor 638316, Fakulti Kejuruteraan Kimia Dan Kejuruteraan Tenaga 599090

Nanofiltration-like forward osmosis membranes with graphene oxide modified polymer-blended subtrate for aerobically-treated palm oil mill effluent treatment / by Wan Nur Ain Shuhada Abdullah, 1994-, author 655804

Rapid and Scalable Production of Functional SARS-CoV-2 Virus-like Particles (VLPs) by a Stable HEK293 Cell Pool by Puarattana-aroonkorn, Sitthiphol, Tharakaraman, Kannan, Suriyawipada, Disapan, Ruchirawat, Mathuros, Fuangthong, Mayuree, Sasisekharan, Ram, Artpradit, Charlermchai

“…We employed the membrane, envelope, and highly immunogenic spike proteins of SARS-CoV-2 to produce virus-like particles (VLPs) using the HEK293-F cell line as a host system with an economical transfection reagent. …”
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Antigen presentation dynamics shape the antibody response to variants like SARS-CoV-2 Omicron after multiple vaccinations with the original strain by Yang, Leerang, Van Beek, Matthew, Wang, Zijun, Muecksch, Frauke, Canis, Marie, Hatziioannou, Theodora, Bieniasz, Paul D, Nussenzweig, Michel C, Chakraborty, Arup K

“…After the first dose, limited antigen availability in germinal centers (GCs) results in a response dominated by B cells that target immunodominant epitopes that are mutated in an Omicron-like variant. After the second dose, these memory cells expand and differentiate into plasma cells that secrete antibodies that are thus ineffective for such variants. …”
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