Dynamical systems guided design and analysis of silicon oscillators for central pattern generators by Cohen, Avis H., Li, Fei, Basu, Arindam, Chang, Chip Hong

“…Dynamical systems analysis has shown that when it is used as a single oscillator, the proposed circuit is able to produce a phase response curve (PRC) close to that of a lamprey CPG system. …”
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An energy-efficient self-adaptive duty cycle MAC protocol for traffic-dynamic wireless sensor networks by Zhao, Yi Zhi, Ma, Maode, Miao, Chun Yan

“…The performance of these protocols drops significantly when network traffic become dynamic or in high traffic load. …”
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Soil suction model for grass evapotranspiration by Ong, Choon Kian

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Behaviour of industrialised building system model in fluid-solid interaction by Farahmandpour, Omolbanin

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The GCSE attainment gap: assessing the influence of permanent school exclusion by Hills, Stephen, Walker, Matthew, Guinn, James, Kent, Aubrey

“…Research has shown that pupils who have been permanently excluded are at a greater risk of negative life outcomes when compared with their non-excluded peers. However, the idea that disadvantaged groups are disproportionately represented amongst those excluded has not previously been tested in prior work. …”
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Synergistic effect of 5-fluorouracil and the small molecule Wnt/β-catenin inhibitor iCRT3 on Caco-2 colorectal cancer cells in vitro by Smarslik, Maren, Inal, Jameel

“…Drug combination significantly increased the IC50 compared to 5-FU, with a 40.95-fold increase (p = 0.0022) when 5-FU was fixed (2.56 μM) and a 43.5-fold increase (p = 0.0023) when iCRT3 was fixed (2.41 μM). …”
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Pyrroloquinoline quinone aza-crown ether complexes as biomimetics for lanthanide and calcium dependent alcohol dehydrogenases by Vetsova, Violeta A., Fisher, Katherine R., Lumpe, Henning, Schäfer, Alexander, Schneider, Erik K., Weis, Patrik, Daumann, Lena J.

“…In addition, we report a new straightforward synthetic route (3 steps instead of 11 and 33 % instead of 0.6 % yield) for biomimetic ligands based on PQQ. We show that when studying biomimetics for MDH, larger metal ions and those with lower charge in this case promote the dehydrogenation reaction more effectively and that this is likely an effect of the ligand design which must be considered when studying biomimetics. …”
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Structured population models for macrophage heterogeneity in early atherosclerosis by Chambers, KL

“…MDMs deeper in the lesion exhibit greater lipid loads and more inflammatory phenotypes. When instead HDL capacity dominates in the blood, mean MDM lipid content is lower and mean MDM phenotype is resolving. …”

Political unrest under IMF programmes: labour mobility, fiscal conditionality, and democratic representation by Metinsoy, S

“…Where labour is mobile, on the other hand, it is easier for workers to switch between sectors and jobs when the economic crisis hits their sector. The labour groups respond to the internal crisis and the external impact by increasing mobility and switching to the sectors that are still growing despite the crisis. …”

Comparative effectiveness of manual therapy, pharmacological treatment, exercise therapy, and education for neck pain (COMPETE study): protocol of a systematic review with network... by de Oliveira-Souza, AIS, Barbosa-Silva, J, Gross, DP, da Costa, BR, Ballenberger, N, Pereira, TV, Dennett, L, Armijo-Olivo, S

“…NMAs will be conducted to rank interventions according to their effectiveness and safety (when possible), allowing a comprehensive analysis of all available evidence, with different nodes specified for all conservative interventions of interest, placebo, sham therapy, and non-intervention control. …”

Controlling selectivity in the reductive activation of CO2 by mixed sandwich uranium(iii) complexes by Tsoureas, N, Castro, L, Kilpatrick, A, Cloke, FGN, Maron, L

“…The nature of the R group on the cyclopentadienyl ring in the former has a significant effect on the outcome of CO2 activation: when R = Me, the products are the bridging oxo complex {U[η8-C8H6(1,4-SiMe3)2](η5-CpMe5)}2(μ-O) and the bridging oxalate complex {U[η8-C8H6(1,4-SiMe3)2](η5-CpMe5)}2(μ-η2:η2-C2O4); for R = Et or iPr, bridging carbonate {U[η8-C8H6(1,4-SiMe3)2](η5-CpMe4R)}2(μ-η1:η2-CO3) and bridging oxalate complexes {U[η8-C8H6(1,4-SiMe3)2](η5-CpMe4R)}2(μ-η2:η2-C2O4) are formed in both cases; and when R = tBu the sole product is the bridging carbonate complex {U[η8-C8H6(1,4-SiMe3)2](η5-CpMe4tBu)}2(μ-η1:η2-CO3). …”

Non-invasive versus arterial pressure monitoring in the pre-hospital critical care environment: a paired comparison of concurrently recorded measurements by Perera, Y, Poole, K, Raitt, J, Metcalfe, D, Lewinsohn, A

“…Clinicians should be cautious when interpreting NIBP measurements and consider direct arterial pressure monitoring when circumstances allow.…”

Preterm birth and cardiometabolic health trajectories from birth to adulthood: the Avon Longitudinal Study of Parents and Children by Clayton, GL, Howe, LD, O’Keeffe, LM, Lewandowski, A, Lawlor, DA, Fraser, A

“…Longer follow-up is needed to establish if and when cardiometabolic health trajectories diverge between these two groups.…”

Artificial intelligence–derived risk prediction: a novel risk calculator using office and ambulatory blood pressure by Guimarães, P, Keller, A, Böhm, M, Lauder, L, Fehlmann, T, Ruilope, LM, Vinyoles, E, Gorostidi, M, Segura, J, Ruiz-Hurtado, G, Staplin, N, Williams, B, de la Sierra, A, Mahfoud, F

“…The area under the curve achieved by the novel approach, already when using OBP variables, was significantly higher when compared with the area under the curve of the Framingham risk score, Systemic Coronary Risk Estimation 2, and Atherosclerotic Cardiovascular Disease score. …”

Combining detection dogs and camera traps improves minimally-invasive population monitoring for the cheetah, an elusive and rare large carnivore by Verschueren, S, Hofmann, T, Schmidt-Küntzel, A, Kakove, M, Munyandi, B, Bauer, H, Balkenhol, N, Leirs, H, Neumann, S, Cristescu, B, Marker, L

“…We found that sign surveys required intensive field effort when walked as road transects, but detections of scat by the detection dogs were twice that of tracks (5/100 and 2.5/100 km, respectively, 7.5/100 km combined). …”

Serological cross-reactivity between Crimean-Congo haemorrhagic fever virus and Nairobi sheep disease virus glycoprotein C by Maze, EA, Booth, G, Limon, G, Belij-Rammerstorfer, S, Tchakarova, SR, Alexandrov, T, Browning, C, Wilsden, G, Ludi, AB, Charleston, B, Lambe, T

“…Cross-reactivity to viruses of the Orthonairovirus genus can potentially interfere with serological assays when employed for serosurveillance in regions where two or more genus members overlap in their distribution. …”

Clinical value of cell-based assays in the characterisation of seronegative myasthenia gravis by Damato, V, Spagni, G, Monte, G, Woodhall, M, Jacobson, L, Falso, S, Smith, T, Iorio, R, Waters, P, Irani, SR, Vincent, A, Evoli, A

“…Overall, patients with SNMG with clustered AChR antibodies, CBA-positive MuSK-MG or triple seronegative were younger, had less severe disease than patients with RIA-positive MG and had a better clinical outcome when immunotherapy was started soon after disease onset, although the time interval from onset to immunotherapy was not different when compared with patients with RIA-positive MG. …”

IGF-1R expression is associated with HPV-negative status and adverse survival in head and neck squamous cell cancer by Dale, OT, Aleksic, T, Shah, KA, Han, C, Mehanna, H, Rapozo, DCM, Sheard, JDH, Goodyear, P, Upile, NS, Robinson, M, Jones, TM, Winter, S, Macaulay, VM

“…IGF-1R was independently associated with survival in multivariate analysis including HPV, but not when lymphovascular invasion, perineural spread and T-stage were included. …”

HELMET: a hybrid machine learning framework for real-time prediction of edema trajectory in large middle cerebral artery stroke by Phillips, E, O'Donoghue, O, Zhang, Y, Tsimpos, P, Mallinger, LA, Chatzidakis, S, Pohlmann, J, Du, Y, Kim, I, Song, J, Brush, B, Smirnakis, S, Ong, CJ, Orfanoudaki, A

“…Malignant cerebral edema occurs when brain swelling displaces and compresses vital midline structures within the first week of a large middle cerebral artery stroke. …”

Evaluating the generalisability of region-naïve machine learning algorithms for the identification of epilepsy in low-resource settings by Duta, I, Kariuki, SM, Ngugi, AK, Mwesige, AK, Masanja, H, Mwanga, DM, Owusu-Agyei, S, Wagner, R, Cross, JH, Sander, JW, Newton, CR, Sen, A, Jones, GD

“…When the models were trained using data from an increasing number of sites, mean internal performance decreased while external performance improved. …”