Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin by Woetmann, Anders, Alhede, Morten, Dabelsteen, Sally, Bjarnsholt, Thomas, Rybtke, Morten, Nastasi, Claudia, Krejsgaard, Thorbjørn, Andersen, Mads Hald, Bonefeld, Charlotte M., Geisler, Carsten, Givskov, Michael, Odum, Niels

“…Here we show that (i) skin T cells in chronic wounds infected with S. aureus express interleukin-26 (IL-26) in situ, (ii) staphylococcal enterotoxins (SE) trigger IL-26 expression in T cell lines and primary skin T cells, and (iii) IL-26 triggers death and inhibits biofilm formation and growth of S. aureus. …”
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Systems medicine disease : disease classification and scalability beyond networks and boundary conditions by Berlin, Richard, Gruen, Russell, Best, James

“…When Disease is viewed beyond the thresholds of lines and threshold boundaries, disease definition is not only the result of reductionist, mechanistic categories which reluctantly face re-composition. …”
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Entangled exclusions: borders, frontiers and urban geopolitics from northeast India by Das, P, Mittal, G, Sarma, J

“…These have, in turn, led to further displacement, enclavization, and ghettoization of minority communities who are deemed ‘non-native’ along ethnocentric lines. Taking two cases from Shillong and Guwahati, we introduce the concept of entangled exclusions to analyse the layered, intertwined, multi-scalar nature of divides within these frontier cities. …”

3D spheroid-microvasculature-on-a-chip for tumor-endothelium mechanobiology interplay by Zhang, Yingqi, Jiang, Fengtao, Zhao, Charles Yunduo, Cho, Ann-Na, Fang, Guocheng, Cox, Charles D., Zreiqat, Hala, Lu, Zu Fu, Lu, Hongxu, Ju, Arnold Lining

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Automatic metric 3D surface mesh generation using subdivision surface geometrical model. Part 1 : construction of underlying geometrical model by Lee, Chi King

“…By using the subdivision surface concept, the new mesh generator can generate finite element meshes to model a wide range of surfaces which may contain sharp features such as cusp points and crease lines. When comparing with other traditional algorithms which use analytical surface patches as the underlying geometrical model, the new mesh generation scheme can be used in applications such as large deformation or crack analyses in which the domains to be gridded are not well defined or involve changing boundaries. …”
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Critical role for cold shock protein YB-1 in cytokinesis by Mehta, Sunali, Algie, Michael, Al-Jabry, Tariq, McKinney, Cushla, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Ma, Weini, Zhang, Jessie, Bartolec, Tara K., Masamsetti, V. Pragathi, Parker, Kim, Henderson, Luke, Gould, Maree L., Bhatia, Puja, Harfoot, Rhodri, Chircop, Megan, Kleffmann, Torsten, Cohen, Scott B., Woolley, Adele G., Cesare, Anthony J., Braithwaite, Antony

“…Here, we found that YB-1 depletion in several cancer cell lines and in immortalized fibroblasts resulted in cytokinesis failure and consequent multinucleation. …”
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Study on supply chain challenges in container shipping : the port operator's perspectice by Muhammad Zulkarnain Mess.

“…Main challenges faced by port operators highlighted in the report include the ever increasing size of vessels, the chronic problem of port congestions and mergers and acquisitions of shipping lines. Some recommendations made for these problems are best practices adopted by ports world wide, while others such as ‘sharing concept’ are derived personally. …”
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Empirical investigation on container port competition and cooperation by Aw, Bing Zong

“…Through empirical investigation and interviews with terminal operators, shipping lines and shippers, this paper aims to investigate the competitive factors in the current economic climate and the effect of sister-port agreements between container ports. …”
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Crypto-linguistics in Singapore : deciphering the Singapore Stone by Chua, Sock Hui

“…The Singapore Stone was a sandstone with around 50 lines of inscription, but was blown up in 1843. A fragment of the original stone now lies in the National Museum of Singapore. …”
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Doxorubicin-loaded cell-derived nanovesicles: an alternative targeted approach for anti-tumor therapy by Goh, Wei Jiang, Lee, Choon Keong, Zou, Shui, Woon, Esther, Czarny, Bertrand, Pastorin, Giorgia

“…Here, we report a systematic approach pertaining to various loading methods of the chemotherapeutic drug doxorubicin into our CDNs and examine the differential cellular uptake of drug-loaded CDNs in cancerous (HeLa) and healthy (HEK293) cell lines. Lastly, we proved that the addition of doxorubicin-loaded CDNs to the HeLa and HEK293 co-cultures showed a clear discrimination toward cancer cells at the cellular level. …”
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Bitcoins in the Malaysian Economy by Miraz, Mahadi Hasan, Mohd Sharif, Kamal Imran, Hassan, Mohamad Ghozali, Ismail, Mohd Azril, Ahmad Mahyadin@Mahidin, Fariza

“…This study focused on individual facts and details, such as articles, reviews, forums, Malaysians brochure, business lines, and research reports. The study relies on secondary data. …”
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Development of differential optical absorption spectroscopy (DOAS) system for hazardous methane gas detection in the near infrared region by Khandaker, Sayma, Hasan, Md Mahmudul, Nurulain Nadhirah, Shaipizaman, Mohd Amir Shahlan, Mohd Aspar, Hadi, Manap

“…An in-depth examination of the absorption lines was conducted to determine the optimal wavelength for measurement. …”
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Hackathons as Participatory Design: Iterating Feminist Utopias by Hope, Alexis, D'Ignazio, Catherine, Hoy, Josephine, Michelson, Rebecca, Roberts, Jennifer, Krontiris, Kate, Zuckerman, Ethan

“…Key to our re-imagining of conventional innovation structures is a focus on experience design, where joy and play serve as key strategies to help people and institutions build relationships across lines of difference. We conclude with a discussion of design principles applicable not only to designers of events, but to social movement researchers and HCI scholars trying to address oppression through the design of technologies and socio-technical systems.…”
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How information about historic carbon emissions affects support for climate aid: evidence from a survey experiment by Charnysh, Volha, Kalow, Jared, Lieberman, Evan, Walk, Erin

“…However, in democratic countries such as the United States, it remains uncertain whether such messages can affect public opinion, especially across partisan lines. We conducted a pre-registered survey from a national online pool (N = 5,002) with a built-in experiment to evaluate the effectiveness of alternative communications strategies associated with historic carbon emissions in increasing support for climate aid. …”
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A novel low-crosstalk driveline based on spoof surface plasmon polaritons by Zhao, Shumin, Zhang, Hao Chi, Liu, Liangliang, Zhao, Jiahao, Yang, Cheng

“…By using traditional drivelines, for example, microstrip lines, the distance between adjacent drivelines should be large enough to reduce the multichannel coupling effects. …”
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Fullwave modeling of coplanar-waveguide discontinuities for applications in filter design and metamaterial characterization by Gao, Jing

“…Coplanar waveguide (CPW) has been finding wide applications in microwave integrated circuit (MIC) and monolithic microwave integrated circuit (MMIC) due to several advantages it offers over microstrip lines. Typical discontinuities characteristics are an integral part of practical circuit design. …”
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New techniques for automated architectural reconstruction from photographs by Werner, T, Zisserman, A

“…Second, we develop and refine a technique for piecewise planar model fitting involving sweeping polygonal primitives, and assess the performance of this technique. Third, lines at infinity are constructed from image correspondences and used to sweep planes in the principal directions. …”

Integrative taxonomy clarifies the evolution of a cryptic primate clade by van Elst, T, Sgarlata, GM, Schüßler, D, Tiley, GP, Poelstra, JW, Scheumann, M, Blanco, MB, Aleixo-Pais, IG, Rina Evasoa, M, Ganzhorn, JU, Goodman, SM, Hasiniaina, AF, Hending, D, Hohenlohe, PA, Ibouroi, MT, Iribar, A, Jan, F, Kappeler, PM, Le Pors, B, Manzi, S, Olivieri, G, Rakotonanahary, AN, Rakotondranary, SJ, Rakotondravony, R

“…Here we illustrate best practices for clarifying cryptic diversification processes by presenting an integrative framework that leverages multiple lines of evidence and taxon-informed cut-offs for species delimitation, while placing special emphasis on identifying patterns of isolation by distance. …”

Antitumor polycyclic acridines. 7. Synthesis and biological properties of DNA affinic tetra- and pentacyclic acridines by Stanslas, Johnson, Hagan, Damien J., Ellis, Michael J., Turner, Claire, Carmichael, James, Ward, Wynne, Hammonds, Timothy R., Stevens, Malcolm F. G.

“…The novel water-soluble agent dihydroindolizino[7,6,5-kl]acridinium chloride 14 has inhibitory activity in a panel of non-small-cell lung and breast tumor cell lines exceeding that of m-AMSA. The salt inhibited the release of minicircle products of kDNA confirming that disorganization of topoisomerase II partly underlies the activity of the compound. …”

Cellular reporter for inflammation. by Yuhanis Abdullah Sunny.

“…Currently, there are commercial green fluorescent protein (GFP) assays available for in vitro cell lines only. There are no in vivo systems that can report NF-B activation in hematopoietic stem cells. …”
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