Cellular studies on the role of OGFOD1, a 2-oxoglutarate-dependent dioxygenase by Attwood, M

“…The transcriptional regulator, Thanatos associated protein 11 (THAP11) was identified as a novel high stoichiometry OGFOD1-interacting protein across a range of cell lines. Analysis of the THAP11 transcriptional programme in SW620 cells defined a repressive action of OGFOD1 overexpression on THAP11 DNA binding and target gene expression. …”

The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells by Pillozzi, Serena, D'Amico, Massimo, Bartoli, Gianluca, Gasparoli, Luca, Petroni, Giulia, Crociani, Olivia, Marzo, Tiziano, Guerriero, Angela, Messori, Luigi, Severi, Mirko, Udisti, Roberto, Wulff, Heike, Chandy, Kanianthara George, Becchetti, Andrea, Arcangeli, Annarosa

“…Methods: The functional expression of Ca2+-activated (KCa3.1, also known as KCNN4) and voltage-dependent (Kv11.1, also known as KCNH2 or hERG1) K+ channels was determined in two CRC cell lines (HCT-116 and HCT-8) by molecular and electrophysiological techniques. …”
Get full text

Induction of apoptosis and the signalling pathways involved by dillenia suffruticosa dichloromethane root extract in mcf-7 and mda-mb-231 breast cancer cells by Foo, Jhi Biau

“…DCMDS induced apoptosis and oxidative stress in these two cell lines. Treatment with α- tocopherol reduced the cytotoxicity of DCM-DS at 50 µg/mL in the cells, suggesting that DCM-DS induced lipid peroxidation to destroy the cancer cells. …”
Get full text

Biogenic amines and urocanic acid in keropok lekor, and their effects on cytotoxicity and proinflammatory mediator secretion of macrophage cell culture by Hussain, Husniza

“…Future research on in vitro cytotoxicity effects of BAs in fishery products or other foods using different cell lines to resemble in vivo study is warranted.…”
Get full text

Three essays on national and organizational cultures by Kawasaki, Shota

“…Chapter 2 illustrates a novel pathway linking employees’ perceptions of organizational cultural strength to job satisfaction and organizational commitment via organizational nostalgia (i.e., one’s sentimental longing or wistful affection for past organizational events). …”
Get full text

Towards Synergistic Understanding of Language Processing in Biological and Artificial Systems by Hosseini Asl, Eghbal

“…Furthermore, the average degree of sentence straightening in the deep layers of the model correlates with corpus-based estimates of sentence surprisal, which are linked to human comprehension difficulty (e.g., as reflected in reading times). Collectively, these lines of work provide essential ingredients for building a more computationally precise model of language processing in the human brain, leveraging synergies with artificial neural network language models.…”
Get full text
Get full text

Development of an application to improve mental health (A) by Khor, Chin Yi

“…As the mental health concern grew, most countries developed new mental health information and phone support lines, offering tips to the public on coping measures. …”
Get full text

杜牧“‘秋’意象诗”研究 = Research on Du Mu’s autumn imagery poems by 林宛仪 Lim, Wan Yi

“…Close reading will be used to uncover the emotions between the lines in Du Mu’s poems that may contain feelings other than grief. …”
Get full text

The effect of the amyloid-beta peptide on the fluidity of cell membranes : a study by fluorescence correlation spectroscopy by Ng, Justin Wei Qing

“…To this end, we used imaging TIRF-fluorescence correlation spectroscopy (ITIR-FCS) to make measurements of fluidity of one bulk membrane probe, DiI, and two ordered/raft-type membrane probes, a transiently expressed GPI-linked GFP and cholera toxin subunit B, on the membranes of living cells that were exposed to Aβ. Three cell lines – SH-SY5Y human neuroblastoma, U87 human glioma and Neuro-2a mouse neuroblastoma – were selected for our study based on their origin in brain tissue and previous use in Aβ-related studies. …”
Get full text

Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes by de Jesus, Daniel S., Mak, Tracy C. S., Wang, Yi-Fang, von Ohlen, Yorrick, Bai, Ying, Kane, Eva, Chabosseau, Pauline, Chahrour, Catherine M., Distaso, Walter, Salem, Victoria, Tomas, Alejandra, Stoffel, Markus, Rutter, Guy A., Latreille, Mathieu

“…We carried out loss- and gain-of-function experiments in MIN6 and EndoC-bH1 cell lines. We analysed previously published mouse andhuman T2D data sets.Results:Bulk RNA-seq revealed thatb-cell dedifferentiation is associated with the induction of genes associated with epithelial-to-mesenchymal transition (EMT) in prediabetic (2-week-old) and diabetic (12-week-old) Tg7 mice. …”
Get full text

Engineering Mechanical Counter Pressure Spacesuits and Compression Garments: Active Pressurization and Design for Mobility by Kothakonda, Akshay

“…The process of estimating the optimum fabric pattern will be iterative and the resulting pattern may comprise of a composite of different fabric types with varying parameters. Mapping skin Lines of Non-Extension (LoNE’s) informs contours for inextensible cables in such a way that they do not impede movements. …”
Get full text

Content-based image retrieval with statistical machine learning. by Zhang, Lining.

Get full text

Investigating the neural substrates of Chinese character processing by Wu, Chiao-Yi

“…The research framework consisted of two levels: direct and converging evidence, through three lines of investigations. Study 1 and Study 2 provided direct evidence of the neural mechanisms for Chinese character processing. …”
Get full text

ESBL and AmpC β-lactamase encoding genes in E. coli from pig and pig farm workers in Vietnam and their association with mobile genetic elements by Hounmanou, Yaovi Mahuton Gildas, Bortolaia, Valeria, Dang, Son Thi Thanh, Truong, Duong, Olsen, John E., Dalsgaard, Anders

“…The isolates carrying the plasmids, even those with plasmids of similar types, showed wide genetic variation with high number of SNPs, suggesting horizontal spread of plasmids into different clonal lines. Their virulence profiles did not confirm to known pathotypes, suggesting that unrelated commensals are a main reservoir for ESBL and AmpC β-lactamases in both humans and pigs. …”
Get full text

Artificial Intelligence in HCI : Second International Conference, AI-HCI 2021, held as part of the 23rd HCI International Conference, HCII 2021, Virtual event, July 24-29, 2021, Pr... by AI-HCI (Conference) (2nd : 2021 : Online), organiser 642919, Degen, Helmut, 1964-, editor 642920, Ntoa, Stavroula, editor 642921, International Conference on Human-Computer Interaction (23rd : 2021 : Online), organiser 642922

Carbon nanotube fence-wall for radio frequency isolation by Tan, Dunlin

“…Passive structures made of microstrip lines and via-fences were first designed using Ansys full wave solver HFSS. …”
Get full text

Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells by Xing, X., Huang, L., Li, X., Li, Z., Zhou, W., Tian, L., Chen, J., Chen, C., Ma, Xing, Yang, Z.

“…And then, we established the stable transfected cell lines. Next, after CVB3 infection, apoptosis in different groups was determined by flow cytometry; the expressions of Bim, Bax, caspase-9 and caspase-3 were examined by real-time fluorescence quantitative PCR and western blot analysis; the expression of CVB3 mRNA and viral capsid protein VP1 were also analyzed by real-time fluorescence quantitative PCR, western blot analysis and immunofluorescence, respectively. …”
Get full text
Get full text

Space charge induced beam loss on a high intensity proton synchrotron by Pine, B

“…Beam will be lost on injection to a synchrotron and may be lost on extraction or in transfer lines. Non-linearities in the accelerator lattice can introduce driving terms for resonant beam behaviour. …”

Rotor angle stability-constrained dispatch and control of large-scale wind penetrated power system by Yuan, Heling

“…In general, four main effects on power system transient stability are: 1) wind generation has no contribution to system inertia and system with synchronous generators replaced by wind turbines will lead to reduction of inertia, 2) power electronics converter-based interfacing is added when wind turbines are implemented, which will change the dynamic behavior of the system, 3) power dispatch of synchronous machines will change fast to compensate wind power variation, 4) the magnitude and direction of power flows will fluctuate quickly and randomly in the transmission lines. Hence, it is an essential and significant problem to maintain system’s stability with high level wind power penetration. …”
Get full text

Evaluating the socio-environmental impacts of monoculture cashew expansion in the Northern Western Ghats, India by Anushka Rege

“…Research along such socio-environmental lines can possibly contribute to the development of sustainability and certification initiatives for cashew. …”
Get full text