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2861
Photonic analog-to-digital conversion and photonic microwave signal generation
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Thesis -
2862
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2863
Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers
Published 2016“…The test compound, sunitinib, was stable in all conditions studied and analyte extraction and detection sensitivity could be improved with sufficient off-line or on-line pre-moistening of the dried spot prior to PS-MS analysis after longer storage period. …”
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Thesis -
2864
Investigations into high resolution imaging of the aqueous outflow system and cornea
Published 2018“…The imaging probe has resolutions of 10.08 line pairs per mm (~49.61 µm) at the iridocorneal angle region and 5.04 line pairs per mm (~99.21 µm) at the fundus. …”
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Thesis-Doctor of Philosophy -
2865
Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity
Published 2018“…Using a novel ‘atom-to-cell’ approach, we establish the basis for the surprisingly site-selective adduct formation behaviour and distinct cellular impact of these two chemically similar anticancer agents, which suggests that the cytotoxic effects arise largely from DNA lesions, whereas the protein adducts may be linked to the other therapeutic activities. Our study shows promise for developing new ruthenium drugs, via ligand-based modulation of DNA versus protein binding and thus cytotoxic potential, to target distinguishing epigenetic features of cancer cells.…”
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Journal Article -
2866
N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5
Published 2018“…Due to its critical role in epigenetics and physiological links to several human diseases, it is also of tremendous biological and medical interest. …”
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Journal Article -
2867
Characterization of the biosynthetic gene cluster and shunt products yields insights into the biosynthesis of balmoralmycin
Published 2022“…Balmoralmycin (compound 1) represents a unique group of angucyclines that contain an angular benz[a]anthracene tetracyclic system, a characteristic C-glycosidic bond-linked deoxy-sugar (D-olivose), and an unsaturated fatty acid chain. …”
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Journal Article -
2868
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2869
Semantic segmentation with less annotation efforts
Published 2020Get full text
Thesis-Doctor of Philosophy -
2870
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2871
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2872
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2873
Decoding divergence in marine protistan communities: from strain diversity to basin biogeography
Published 2024“…Scalable workflows highlight the challenge and promise of meta-omic data to link community structure to physiology. I developed a pipeline for metatranscriptome analysis and taxonomic annotation to address the lack of tools built specifically for microbial eukaryotes, and created mock communities to assess recovery success in protistan metatranscriptome analysis workflows (Chapters 4 and 5). …”
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Thesis -
2874
Mechanics of Three-Dimensional Micro-Architected Interpenetrating Phase Composites
Published 2024“…Altogether, this work broadens our established understanding of the link between architecture and mechanical performance by considering the framework of interpenetrating phase composites, creating the foundation for a new class of strong, resilient, and programmable materials with architected stress states.…”
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Thesis -
2875
LEO satellite formation for SSP : energy and doppler analysis
Published 2015“…In this paper, first, the transmission link budget from LEO and geostationary orbits to the Earth are compared, and the harvested energy by the ground station on the Earth is investigated. …”
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Journal Article -
2876
Threshold estimation models for linear threshold-based influential user mining in social networks
Published 2019Get full text
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Journal Article -
2877
Distributed hierarchical control of AC microgrid operating in grid-connected, islanded and their transition modes
Published 2019“…In addition, stability analysis is added to facilitate the control parameter designs, and substantial simulation cases are provided to validate the control feasibility, link-failure-resiliency, and plug-and-play capability.…”
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Journal Article -
2878
Functional homogeneity and specificity of topological modules in human proteome
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Journal Article -
2879
Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm
Published 2015“…This work provides insights in understanding cell fate transcriptional regulation by highlighting the direct link between the DNA sequence of an enhancer and a developmental outcome.…”
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Journal Article -
2880