Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans by Xu, Luang, Liu, Xinyu, Sheng, Na, Oo, Kyaw Soe, Liang, Junxin, Chionh, Yok Hian, Xu, Juan, Ye, Fuzhou, Gao, Yong-Gui, Dedon, Peter C., Fu, Xin-Yuan

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Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation by Kalailingam, Pazhanichamy, Tan, Hui Bing, Jain, Neeraj, Sng, Ming Keat, Chan, Jeremy Soon Kiat, Tan, Nguan Soon, Thanabalu, Thirumaran

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Epithelial-mesenchymal transition of cancer cells using bioengineered hybrid scaffold composed of hydrogel/3D-fibrous framework by Pal, Mintu, Chen, Huizhi, Lee, Bae Hoon, Lee, Justin Yin Hao, Yip, Yun Sheng, Tan, Nguan Soon, Tan, Lay Poh

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Two models of dark triad traits and self-regulation dilemma predicting IP theft through self-deception by Yeo, Diana Mui Kheng

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Application of magnetic field for reduction of sludge bulking in activated sludge system by Zaidi, Nur Syamimi

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Optimization, encapsulation and characterization of bromelain-generated angiotensin I-converting enzyme (Ace) - inhibitory hydrolysates from stone fish (Actinopyga lecanora Jaeger) by Auwal, Shehu Muhammad

“…A pH of 7.0, temperature of 40oC, E/S ratio of 2% and reaction time of 240 min were determined using a response surface model as the optimum levels to obtain the hydrolysates with maximum ACE-inhibitory activity of 84.26% at 44.59% degree of hydrolysis. …”
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Pembinaan Model Integratif Peningkatan Ketahanan Psikososial Remaja (MIPKPR) untuk Pemantapan Resiliensi Remaja Hamil Tanpa Nikah (S/O: 14186) by Shaffie, Fuziah, Abu Bakar, Md Zawawi, Mohd Ariffin, Nurhazlina, Mahamood, Yahaya

“…Dapatan kajian kuantitatif menunjukkan bahawa RHTN di rumah perlindungan mempunyai tahap resiliensi yang sederhana (Min=3.40, Sisihan Piawai=1.010) dan tiada perbezaan tahap resiliensi yang signifikan bagi responden di rumah perlindungan kerajaan dan swasta (t= -0.53, df=5.85, p>.05). …”
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Hybrid mesoporous microbeads based on sheets-like sulfur-doped copper oxide embedded in calcium alginate-derived carbon for batch and columnar adsorption of cationic dye by Naggar, Ahmed H., Alshammari, Mutairah S., Seaf-Elnasr, Tarek A., Chong, Kwok Feng, Bakr, Zinab H., Alotaibi, N. F., Ali, Hazim M., El-Nasser, Karam S., Thabet, Mahmoud, Abd El-Monaem, Eman M., Goda, Adel E. S., Gomaa, Hassanien

“…The columnar adsorption tests showed that the adsorption capacity of SCO@CACBs varied from 83.6 to 71.3 mg/g as the flow rate varied from 2 to 6 mL/min and 81.5–115.6 mg/g as the adsorbent mass varied from 1 to 4 g. …”
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Individual, clinical and system factors associated with the place of death : a linked national database study by Tan, Woan Shin, Bajpai, Ram, Low, Chan Kee, Ho, Andy Hau Yan, Wu, Huei Yaw, Car, Josip

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Temporal pressure enhanced topical drug delivery through micropore formation by Lio, Daniel Chin Shiuan, Chia, Ruining, Kwek, Milton Sheng Yi, Wiraja, Christian, Madden, Leigh Edward, Chang, Hao, S. Mohideen Abdul Khadir, Wang, Xiaomeng, Becker, David Lawrence, Xu, Chenjie

“…The creation of micropores (~3 μm2) on the epidermal layer through a temporal pressure treatment results in the elevated expression of gap junctions, and reduced expression of occludin tight junctions. A 1 min treatment of 0.28-MPa allows nanoparticles (up to 500 nm) and macromolecules (up to 20 kDa) to reach a depth of 430-μm into the dermal layer. …”
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新加坡福建话马来语及英借词使用情况调查 = Usage of English and Malay loanwords amongst Singapore Hokkien speakers by 张良忆 Teo, Joey Liang Yi

“…Hokkien being the most widely spoken dialect in Singapore, has therefore attracted much attention. Compared to other Min dialects, Hokkien in Singapore consist of a large number of English and Malay loanwords. …”
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Active learning for ontological event extraction incorporating named entity recognition and unknown word handling by Han, Xu, Kim, Jung-jae, Kwoh, Chee Keong

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Effectiveness of a chronic obstructive pulmonary disease integrated care pathway in a regional health system : a propensity score matched cohort study by Wu, Christine Xia, Hwang, Chi Hong, Tan, Woan Shin, Tai, Kai Pik, Kwek, Lynette Siang Lim, Chee, Thong Gan, Choo, Yee Mun, Phng, Francis Wei Loong, Chua, Gerald Seng Wee

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Ergogenic and metabolites analyses of piyarom date (Phoenix dactylifera L.) using NMR-based metabolomics and its effect on Sprague dawley rats by Shanan, Hana Kadum

“…Results of in vivo study showed that rats treated with 500 mg/kg BW Piyarom date extract demonstrated the longest endurance capacity of 10 min, that is significantly higher than that of caffeine-treated rats, as measured by forced swimming test. …”
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Culture of human pluripotent stem cells and neural networks in 3D using an optogenetic approach and a hydrogel model by Lee, S

“…Investigation of cell response reveals that a flow rate of 3 ml/min and an alginate concentration of 1.8% (w/v) are optimal and that stem cell survival is significantly improved through incorporation of RGD and ROCKi. …”

Multi-colony coral skeletal Ba/Ca from Singapore’s turbid urban reefs : relationship with contemporaneous in-situ seawater parameters by Tanzil, Jani Thuaibah Isa, Goodkin, Nathalie Fairbank, Sin, T. M., Chen, Mengli, Fabbro, Gareth Nicholas, Boyle, E. A., Lee, A. C., Toh, K. B.

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Electrospun carbon-silica composite nanofibers for selective removal of oil and water by Tai, Ming Hang

“…After surface-coating with silicone oil for 30 min, the composite membrane exhibited ultra-hydrophobic and superoleophilic properties with water and oil contact angles being 144.2 ± 1.2° and 0°, respectively. …”
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Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration by Goh, Catherine Wenhui, Lee, Irene Chengjie, Sundaram, Jeyapriya Rajameenakshi, George, Simi Elizabeth, Yusoff, Permeen, Brush, Matthew Hayden, Sze, Newman Siu Kwan, Shenolikar, Shirish

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Establishment of optimise strategies in production of recombinant Hepatitis B surface antigen for chip-based antibody detection approach by Tam, Yew Joon

“…The main results drawn showed that the IEC Q Sepharose XL column and optimum conditions of 4 mL sample loading volume, an elution buffer with 1.5 M NaCl concentration at pH 8 with an elution gradient length of 20 column volume and subsequent purification with SEC at a sample volume of 5 mL and a flow rate of 1 mL/min was able to efficiently purify HBsAg. An up-scaled version the established purification strategy comprising of the two techniques further demonstrated adaptability for scale-up operations with a final total PF of 94.82 ± 16.20, HBsAg purity of 95.48% and recovery yield of 78.07%. …”
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Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes by de Jesus, Daniel S., Mak, Tracy C. S., Wang, Yi-Fang, von Ohlen, Yorrick, Bai, Ying, Kane, Eva, Chabosseau, Pauline, Chahrour, Catherine M., Distaso, Walter, Salem, Victoria, Tomas, Alejandra, Stoffel, Markus, Rutter, Guy A., Latreille, Mathieu

“…We carried out loss- and gain-of-function experiments in MIN6 and EndoC-bH1 cell lines. We analysed previously published mouse andhuman T2D data sets.Results:Bulk RNA-seq revealed thatb-cell dedifferentiation is associated with the induction of genes associated with epithelial-to-mesenchymal transition (EMT) in prediabetic (2-week-old) and diabetic (12-week-old) Tg7 mice. …”
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