High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer by Palafox, Marta, Monserrat, Laia, Bellet, Meritxell, Villacampa, Guillermo, Gonzalez-Perez, Abel, Oliveira, Mafalda, Brasó-Maristany, Fara, Ibrahimi, Nusaibah, Kannan, Srinivasaraghavan, Mina, Leonardo, Herrera-Abreu, Maria Teresa, Òdena, Andreu, Sánchez-Guixé, Mònica, Capelán, Marta, Azaro, Analía, Bruna, Alejandra, Rodríguez, Olga, Guzmán, Marta, Grueso, Judit, Viaplana, Cristina, Hernández, Javier, Su, Faye, Lin, Kui, Clarke, Robert B., Caldas, Carlos, Arribas, Joaquín, Michiels, Stefan, García-Sanz, Alicia, Turner, Nicholas C., Prat, Aleix, Nuciforo, Paolo, Dienstmann, Rodrigo, Verma, Chandra Shekhar, Lopez-Bigas, Nuria, Scaltriti, Maurizio, Arnedos, Monica, Saura, Cristina, Serra, Violeta

“…Here, we show that p16 overexpression is associated with reduced antitumor activity of CDK4/6 inhibitors in patient-derived xenografts (n = 37) and estrogen receptor-positive breast cancer cell lines, as well as reduced response of early and advanced breast cancer patients to CDK4/6 inhibitors (n = 89). …”
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Novel method of probe design for characterising unclassified microbial taxa in wastewater by Tan, Shi Ming

“…Shimingles; distinct clades were in line with two draft genomes recovered through genomic binning. …”
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InAlN/GaN high electron mobility transistors on Si for RF applications by Xing, Weichuan

“…Also, device geometries including gate length, line-to-space ratio of the nanostripchannel and gate-to-source distance have been studied. …”
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Higher-order moments of the elliptic flow distribution in PbPb collisions at $$ \sqrt{s_{\textrm{NN}}} $$ = 5.02 TeV by Tumasyan, A., Adam, W., Andrejkovic, J. W., Bergauer, T., Chatterjee, S., Damanakis, K., Dragicevic, M., Escalante Del Valle, A., Hussain, P. S., Jeitler, M., Krammer, N., Lechner, L., Liko, D., Mikulec, I., Paulitsch, P., Pitters, F. M., Schieck, J., Schöfbeck, R., Schwarz, D., Sonawane, M., Templ, S., Waltenberger, W., Wulz, C.-E., Darwish, M. R., Janssen, T., Kello, T., Rejeb Sfar, H., Van Mechelen, P., Bols, E. S., D’Hondt, J., De Moor, A., Delcourt, M., El Faham, H., Lowette, S., Moortgat, S., Morton, A., Müller, D., Sahasransu, A. 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Effect of dopant solubility and excess doping on the superconducting properties of doped Nb3Sn prepared by field assisted sintering technique by Srivastava, N, Matthews, GAB, Liu, J, Speller, SC, Grovenor, CRM, Santra, S

“…The Y₂O₃&nbsp;particles was also considered as a possible cause of pinning down of grain boundaries in addition to NbO leading to grain refinement through Zener pinning. …”

Comparison of different cooling strategies in achieving desired crystal size distribution for seeded potash alum crystallization process by Siti Zubaidah, Adnan, Noor Asma Fazli, Abdul Samad

“…Based on the simulation results, strategy I delivers the smallest size of CSD with high fines or small-sized crystals, while strategy II provides large CSD but with significant number of fines. …”
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Spintronics devices for neuromorphic computing by Tang, Shawn Zhen Kee

“…To solve this, we discuss the possibility of using a geometrically pinned magnetic domain wall memory device that utilises anti-notches for pinning, as the free layer of an MTJ, for future use in a three-terminal MRAM. …”
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Software defined network : user centric network by Lim, Derrick Teck Leong.

“…A test of the application was done by running two continuous pings, one from each host to the other. Then, the path in use was disconnected. …”
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Target Design and Optimizations for Spent Fuel Transmutation by Tukharyan, Grigor

“…A proposed tank design with a lead/Tc-99 target that is surrounded by LLFP pins and heavy water is considered for the spallation study. …”
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Dynamics of three-dimensional helical domain wall in cylindrical NiFe nanowires by Wong, De Wei, Chandra Sekhar, M., Gan, Wei Liang, Purnama, Indra, Lew, Wen Siang

“…A minimum current density is needed to overcome an intrinsic pinning to drive the helical DW, and the propagation along the nanowire is accompanied by a rotational motion. …”
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Application for motorised video sliding kit by Gao, Cheng

“…Arduino is used to control Pan and Tilt Head and servo motor through PWM pins. At the end of this project, an integrated solution to automate time-lapse photography is developed. …”
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Bilayer skyrmion dynamics on a magnetic anisotropy gradient by Ang, Calvin Ching Ian, Gan, Weiliang, Lew, Wen Siang

“…Furthermore, the analytical model also provides insights into the dynamics of skyrmion pinning and relaxation of asymmetric skyrmion pairs in bilayer-coupled skyrmion systems.…”
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Emergent vortices at a ferromagnetic superconducting oxide interface by Petrović, A P, Paré, A, Paudel, T R, Lee, K, Holmes, S, Barnes, C H W, David, A, Wu, T, Tsymbal, E Y, Panagopoulos, C

“…This hysteresis is argued to arise from vortex depinning within a thin (< 20 nm) superconducting layer, mediated by discrete ferromagnetic dipoles located solely above the layer. The pinning strength may be modified by varying the superconducting channel thickness via electric field-effect doping. …”
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Goblet cell differentiation in colorectal cancer by Abdullayeva, G

“…These groups included high, medium, and low MUC2/TFF3-expressing cell lines, cell lines with no/very low MUC2 but high TFF3 expression, and cell lines completely lacking these proteins. …”

Numerical modeling of the morphological change in Lhok Nga, west Banda Aceh, during the 2004 Indian Ocean tsunami : understanding tsunami deposits using a forward modeling method by Li, Linlin, Qiu, Qiang, Huang, Zhenhua

“…Phenomena such as landward thinning in deposit thickness, landward fining in grain size, and fining upwards in grain size are commonly used to identify tsunami deposits and were examined in this case study. …”
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Subprime crisis : the impact of different types of debt on corporate performance. by Lim, Chee Hau., Neo, Wei Ling., Lim, Brandon Weilong.

“…For pre-crisis to crisis period, result indicates that firms possessing pre-existing Undrawn Credit Lines during the pre-crisis period would not perform significantly better than firms which did not have access to Undrawn Credit Lines. …”
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Improving gene therapy by Wang, Eliza Lisha

“…Existing PT67 and Amphotropic-Phoenix retroviral packaging cell lines can be made more efficient to produce higher retroviral titers, giving rise to more efficient gene transfer. …”
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