Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial by Silk, SE, Kalinga, WF, Salkeld, J, Mtaka, IM, Ahmed, S, Milando, F, Diouf, A, Bundi, CK, Balige, N, Hassan, O, Mkindi, CG, Rwezaula, S, Athumani, T, Mswata, S, Lilolime, NS, Simon, B, Msami, H, Mohamed, M, David, DM, Mohammed, L, Nyaulingo, G, Mwalimu, B, Juma, O, Mwamlima, TG, Sasamalo, IA, Mkumbange, RP, Kamage, JJ, Barrett, JR, King, LDW, Hou, MM, Pulido, D, Carnrot, C, Lawrie, AM, Cowan, RE, Nugent, FL, Roberts, R, Cho, J-S, Long, CA, Nielsen, CM, Miura, K, Draper, SJ, Olotu, AI, Minassian, AM

“…<p><strong>Background:</strong> A blood-stage Plasmodium falciparum malaria vaccine would provide a second line of defence to complement partially effective or waning immunity conferred by the approved pre-erythrocytic vaccines. …”

High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer by Palafox, Marta, Monserrat, Laia, Bellet, Meritxell, Villacampa, Guillermo, Gonzalez-Perez, Abel, Oliveira, Mafalda, Brasó-Maristany, Fara, Ibrahimi, Nusaibah, Kannan, Srinivasaraghavan, Mina, Leonardo, Herrera-Abreu, Maria Teresa, Òdena, Andreu, Sánchez-Guixé, Mònica, Capelán, Marta, Azaro, Analía, Bruna, Alejandra, Rodríguez, Olga, Guzmán, Marta, Grueso, Judit, Viaplana, Cristina, Hernández, Javier, Su, Faye, Lin, Kui, Clarke, Robert B., Caldas, Carlos, Arribas, Joaquín, Michiels, Stefan, García-Sanz, Alicia, Turner, Nicholas C., Prat, Aleix, Nuciforo, Paolo, Dienstmann, Rodrigo, Verma, Chandra Shekhar, Lopez-Bigas, Nuria, Scaltriti, Maurizio, Arnedos, Monica, Saura, Cristina, Serra, Violeta

“…Here, we show that p16 overexpression is associated with reduced antitumor activity of CDK4/6 inhibitors in patient-derived xenografts (n = 37) and estrogen receptor-positive breast cancer cell lines, as well as reduced response of early and advanced breast cancer patients to CDK4/6 inhibitors (n = 89). …”
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Novel method of probe design for characterising unclassified microbial taxa in wastewater by Tan, Shi Ming

“…Shimingles; distinct clades were in line with two draft genomes recovered through genomic binning. …”
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InAlN/GaN high electron mobility transistors on Si for RF applications by Xing, Weichuan

“…Also, device geometries including gate length, line-to-space ratio of the nanostripchannel and gate-to-source distance have been studied. …”
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Higher-order moments of the elliptic flow distribution in PbPb collisions at $$ \sqrt{s_{\textrm{NN}}} $$ = 5.02 TeV by Tumasyan, A., Adam, W., Andrejkovic, J. W., Bergauer, T., Chatterjee, S., Damanakis, K., Dragicevic, M., Escalante Del Valle, A., Hussain, P. S., Jeitler, M., Krammer, N., Lechner, L., Liko, D., Mikulec, I., Paulitsch, P., Pitters, F. M., Schieck, J., Schöfbeck, R., Schwarz, D., Sonawane, M., Templ, S., Waltenberger, W., Wulz, C.-E., Darwish, M. R., Janssen, T., Kello, T., Rejeb Sfar, H., Van Mechelen, P., Bols, E. S., D’Hondt, J., De Moor, A., Delcourt, M., El Faham, H., Lowette, S., Moortgat, S., Morton, A., Müller, D., Sahasransu, A. 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S., Zarubin, A., Zhizhin, I., Zhokin, A.

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Multi-site benchmark classification of major depressive disorder using machine learning on cortical and subcortical measures by Belov, Vladimir, Erwin-Grabner, Tracy, Aghajani, Moji, Aleman, Andre, Amod, Alyssa R., Basgoze, Zeynep, Benedetti, Francesco, Besteher, Bianca, Bülow, Robin, Ching, Christopher R. K., Connolly, Colm G., Cullen, Kathryn, Davey, Christopher G., Dima, Danai, Dols, Annemiek, Evans, Jennifer W., Fu, Cynthia H. Y., Gonul, Ali Saffet, Gotlib, Ian H., Grabe, Hans J., Groenewold, Nynke, Hamilton, J. Paul, Harrison, Ben J., Ho, Tiffany C., Mwangi, Benson, Jaworska, Natalia, Jahanshad, Neda, Klimes-Dougan, Bonnie, Koopowitz, Sheri-Michelle, Lancaster, Thomas, Li, Meng, Linden, David E. J., MacMaster, Frank P., Mehler, David M. A., Melloni, Elisa, Mueller, Bryon A., Ojha, Amar, Oudega, Mardien L., Penninx, Brenda W. J. H., Poletti, Sara, Pomarol-Clotet, Edith, Portella, Maria J., Pozzi, Elena, Reneman, Liesbeth, Sacchet, Matthew D., Sämann, Philipp G., Schrantee, Anouk, Sim, Kang, Soares, Jair C., Stein, Dan J., Thomopoulos, Sophia I., Uyar-Demir, Aslihan, van der Wee, Nic J. A., van der Werff, Steven J. A., Völzke, Henry, Whittle, Sarah, Wittfeld, Katharina, Wright, Margaret J., Wu, Mon-Ju, Yang, Tony T., Zarate, Carlos, Veltman, Dick J., Schmaal, Lianne, Thompson, Paul M., Goya-Maldonado, Roberto

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Software defined network : user centric network by Lim, Derrick Teck Leong.

“…A test of the application was done by running two continuous pings, one from each host to the other. Then, the path in use was disconnected. …”
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Goblet cell differentiation in colorectal cancer by Abdullayeva, G

“…These groups included high, medium, and low MUC2/TFF3-expressing cell lines, cell lines with no/very low MUC2 but high TFF3 expression, and cell lines completely lacking these proteins. …”

Improving gene therapy by Wang, Eliza Lisha

“…Existing PT67 and Amphotropic-Phoenix retroviral packaging cell lines can be made more efficient to produce higher retroviral titers, giving rise to more efficient gene transfer. …”
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Automatic vanishing points detection for single view reconstruction by Potcharaphol, Chat Anan

“…The algorithm is found to be fast and effective for an image with clear feature lines but struggles with an image with few feature lines. …”
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Perceptual watermarking and data concealment in audio signals by Tio, Cedric Meng Meng.

“…This project aims to hide data in audio streams by direct substitution of the FFT spectral lines with the hidden data. The spectral lines to be replaced are carefully chosen with the help of a psychoacoustic model. …”
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POPX2 and its role in breast cancer. by Susila, Agatha.

“…We found that POPX2 is highly expressed in cancer cell lines compared to non-cancer cell lines.…”
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Information pollution and the war in Gaza: implications for Singapore by Wong, Yasmine, Haciyakupoglu, Gulizar

“…Besides demonstrating various disinformation types and tactics, there is also the increased resonance of certain disinformation narratives as they overlap and impact on societal sensitivities and identity-based fault lines. These are challenges for Singapore, as societal fault lines present vulnerabilities for disinformation penetration, ultimately affecting social cohesion.…”
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General circulation models simulate negative liquid water path–droplet number correlations, but anthropogenic aerosols still increase simulated liquid water path by Mülmenstädt, J, Gryspeerdt, E, Dipu, S, Quaas, J, Ackerman, AS, Fridlind, AM, Tornow, F, Bauer, SE, Gettelman, A, Ming, Y, Zheng, Y, Ma, P-L, Wang, H, Zhang, K, Christensen, MW, Varble, AC, Leung, LR, Liu, X, Neubauer, D, Partridge, DG, Stier, P, Takemura, T

“…These results are a reminder that assessments of climate parameters based on multiple lines of evidence must carefully consider the complementary strengths of different lines when the lines disagree.…”

Characterization of artemisinin resistance in plasmodium falciparum by Rocamora, Frances Maureen C.

“…Long term in vitro selection produced two parasite lines that displayed profound stage-specific resistance to artemisinin and its relative compounds. …”
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Assessing the financial performance of container shipping companies by Cai, Kewei

“…Over the past few decades, a phenomenon was observed where container shipping lines are adapting vertical integration strategies towards the ports and logistics market, which is outside of their core business. …”
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Singapore boreholes results with numerical and analytical simulation by Yap, Kai Xian

“…To achieve this, the final year project outlined in this report will leverage advanced computer software to simulate various tunnel lining designs across different soil profiles specific to Singapore. …”
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Small spherical and projective codes by Cohn, Henry

“…This data set describes the best spherical and real projective codes that are known to exist (to the best of my knowledge), for up to 32 points on spheres or 16 lines through the origin in the real projective case. …”
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Humanity's dark side: coping with a failing world order by John, Lord Alderdice

“…Various crises have exposed fault-lines in the existing global order. It has spotlighted the existing differences in ideologies across the world. …”
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The chronicles of cerebrovascular aging: an epic transcriptomic tale by Nguyen, Le Uyen Nhi

“…Endothelial cells are the lining of blood vessels, these cells play a crucial role in maintaining vascular integrity. …”
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