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2101
Performance-based identity in a BIM environment : An architect’s perceptions and experiences
Published 2022“…Consequently, architects' failing to adapt their core identity to the varying circumstances may lead to their irrelevance and being side-lined merely as aesthetic building surgeons. The current study therefore seeks a better understanding of their perceptions and experiences in manifesting their identities in the phenomenon. …”
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Article -
2102
Tablets, Pens, and Pencils: The Influence of Tools on Sketching in Early Stage Design
Published 2024“…We hypothesize that participants using tablet and pencil will produce fewer drawings than those using pen due to their ability to erase and focus on perfecting drawings, and we expect participants using the tablet to produce cleaner drawings with smoother strokes due to the tablet’s ability to auto-smooth lines. Based on prior literature, we posit that women and gender minorities will produce fewer sketches and use the feathering style of sketching more than men.…”
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Article -
2103
Regulation of microRNA degradation in Caenorhabditis elegans via the E3 ubiquitin ligase EBAX-1
Published 2024“…TDMD underlies the instability of many miRNAs in diverse cell lines and animals. In this work, I probe the biological scope of TDMD as a regulatory mechanism in the nematode Caenorhabiditis elegans, which tolerates homozygous loss of the ZSWIM8 ortholog, EBAX-1, and expresses some miRNAs that are subject to rapid, developmentally regulated decay. …”
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Thesis -
2104
Development of immunomodulatory RNA therapeutics for immune disorders
Published 2022“…We show that these ASOs can modulate T cell behavior in human cell lines and human primary cells, validating the potential of ASOs as a therapeutic approach for immune diseases. …”
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Thesis-Doctor of Philosophy -
2105
Data-driven distributionally robust CVaR portfolio optimization under a regime-switching ambiguity set
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Journal Article -
2106
Financial forecasting using meta-cognitive fuzzy neural networks
Published 2014“…The primary meta-cognitive strategies are Sample deletion, Sample Learning and Sample Reserve. Following on the lines of Technical Analysis carried out by traders and investors on the historical prices of a company’s stock, the project makes use of various Financial Indicators to decide whether a particular instance of time is good for investment, disinvestment or to remain idle. …”
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Final Year Project (FYP) -
2107
Taliban resurgence in Afghanistan : the role of post-conflict reconstruction
Published 2015“…Under the auspices of Bonn-I, the international community initiated a process of post-conflict reconstruction on both security and non-security lines. Bonn-I provided a framework for setting up an interim government tasked with drafting a constitution, convening a Loya Jirga (grand assembly), holding presidential and parliamentary elections by 2005, strengthening the Afghan police and military forces, and establishing a judicial system. …”
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Thesis -
2108
Multi-spectral polarimetry imaging for early gastric cancer diagnosis
Published 2016“…Gastric cancer, which develops from the lining of stomach, is the fifth most severe disease worldwide. …”
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Thesis -
2109
Cellular studies on the role of OGFOD1, a 2-oxoglutarate-dependent dioxygenase
Published 2017“…The transcriptional regulator, Thanatos associated protein 11 (THAP11) was identified as a novel high stoichiometry OGFOD1-interacting protein across a range of cell lines. Analysis of the THAP11 transcriptional programme in SW620 cells defined a repressive action of OGFOD1 overexpression on THAP11 DNA binding and target gene expression. …”
Thesis -
2110
The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells
Published 2020“…Methods: The functional expression of Ca2+-activated (KCa3.1, also known as KCNN4) and voltage-dependent (Kv11.1, also known as KCNH2 or hERG1) K+ channels was determined in two CRC cell lines (HCT-116 and HCT-8) by molecular and electrophysiological techniques. …”
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Journal Article -
2111
Towards depth-resolved multi-cubic-centimeter field of view endoscopic camera for intraoperative nerve identification.
Published 2024“…In the second component of this thesis, we provide extensive theoretical and experimental studies on how optical amplifiers can be used in OCT to address sensitivity challenges of high-speed surgical OCT platforms like CL-OCT. Together, these lines of research define a new approach to meeting the need for OCT-based solutions for intraoperative nerve identification. …”
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Thesis -
2112
P2P energy trading among isolated microgrids in the remote area
Published 2021“…As for the power supply in remote areas, the traditional transmission method by using the central grid has the drawbacks of large transmission loss and long transmission lines, which are easy to be broken. At the same time, there are areas where electricity is not available because of costly transmission losses, for the transmission networks are not yet widespread. …”
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Thesis-Master by Coursework -
2113
Induction of apoptosis and the signalling pathways involved by dillenia suffruticosa dichloromethane root extract in mcf-7 and mda-mb-231 breast cancer cells
Published 2015“…DCMDS induced apoptosis and oxidative stress in these two cell lines. Treatment with α- tocopherol reduced the cytotoxicity of DCM-DS at 50 µg/mL in the cells, suggesting that DCM-DS induced lipid peroxidation to destroy the cancer cells. …”
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Thesis -
2114
Biogenic amines and urocanic acid in keropok lekor, and their effects on cytotoxicity and proinflammatory mediator secretion of macrophage cell culture
Published 2017“…Future research on in vitro cytotoxicity effects of BAs in fishery products or other foods using different cell lines to resemble in vivo study is warranted.…”
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Thesis -
2115
Towards Synergistic Understanding of Language Processing in Biological and Artificial Systems
Published 2024“…Furthermore, the average degree of sentence straightening in the deep layers of the model correlates with corpus-based estimates of sentence surprisal, which are linked to human comprehension difficulty (e.g., as reflected in reading times). Collectively, these lines of work provide essential ingredients for building a more computationally precise model of language processing in the human brain, leveraging synergies with artificial neural network language models.…”
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Thesis -
2116
Development of an application to improve mental health (A)
Published 2023“…As the mental health concern grew, most countries developed new mental health information and phone support lines, offering tips to the public on coping measures. …”
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Final Year Project (FYP) -
2117
Grid optimization and demand side mangement for electric vehicles penetration in remote area
Published 2023“…Power grid model simulation: use government data to predict that Trincomalee's electricity demand will increase from the current 40MW to 640MW in five years and build a grid simulation model for Sri Lanka's national high-voltage transmission lines. Optimization will target transmission cables that provide higher voltage loads while considering cable properties includes resistance and reactance for optimal power loss and voltage drop respectively, thermal capacity, and power quality. …”
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Conference Paper -
2118
杜牧“‘秋’意象诗”研究 = Research on Du Mu’s autumn imagery poems
Published 2012“…Close reading will be used to uncover the emotions between the lines in Du Mu’s poems that may contain feelings other than grief. …”
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Final Year Project (FYP) -
2119
The effect of the amyloid-beta peptide on the fluidity of cell membranes : a study by fluorescence correlation spectroscopy
Published 2017“…To this end, we used imaging TIRF-fluorescence correlation spectroscopy (ITIR-FCS) to make measurements of fluidity of one bulk membrane probe, DiI, and two ordered/raft-type membrane probes, a transiently expressed GPI-linked GFP and cholera toxin subunit B, on the membranes of living cells that were exposed to Aβ. Three cell lines – SH-SY5Y human neuroblastoma, U87 human glioma and Neuro-2a mouse neuroblastoma – were selected for our study based on their origin in brain tissue and previous use in Aβ-related studies. …”
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Thesis -
2120
Climate change: crop performance and potential
Published 2011“…In addition, a biological control using other species of bamboo to reduce the domination of buluh semantan under high voltage transmission lines is also included. In the studies regarding growth of forest species meant for domestication purposes, the suitability of Syzygium campanulatum and Hopea odorata for beautification and landscaping plants has shown some potential. …”
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Inaugural Lecture