PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism by Salvadó, Laia, Barroso, Emma, Gómez-Foix, Anna Maria, Palomer, Xavier, Michalik, Liliane, Wahli, Walter, Vázquez-Carrera, Manuel

“…Methods Studies were conducted in mouse C2C12 myotubes, in the human myogenic cell line LHCN-M2 and in skeletal muscle from wild-type and PPARβ/δ-deficient mice and mice exposed to a high-fat diet. …”
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Optical coherence tomography angiography imaging to monitor anti-VEGF treatment of corneal vascularization in a rabbit model by Devarajan, Kavya, Ong, Hon Shing, Lwin, Nyein C., Chua, Jacqueline, Schmetterer, Leopold, Mehta, Jodhbir Singh, Ang, Marcus

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PPARβ/δ agonism upregulates forkhead box A2 to reduce inflammation in C2C12 myoblasts and in skeletal muscle by Phua, Wendy Wen Ting, Tan, Wei Ren, Yip, Yun Sheng, Hew, Ivan Dongzheng, Wee, Jonathan Wei Kiat, Cheng, Hong Sheng, Leow, Melvin Khee Shing, Wahli, Walter, Tan, Nguan Soon

“…This reduced local inflammatory response limits tissue damage and restores muscle tetanic contraction. In line with these results, a deficiency in either PPARβ/δ or FoxA2 diminishes the action of the PPARβ/δ agonist GW501516 to suppress an aggravated inflammatory response. …”
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Viral proteases activate the CARD8 inflammasome in the human cardiovascular system by Nadkarni, Rhea, Chu, Wern Cui, Lee, Cheryl Q. E., Mohamud, Yasir, Yap, Lynn, Toh, Gee Ann, Beh, Sheryl, Lim, Radiance, Fan, Michelle Yiyun, Zhang, Lyanne Yizhuo, Robinson, Kim, Tryggvason, Karl, Luo, Honglin, Zhong, Franklin, Ho, Lena

“…The endothelium is the first line of defense against blood-borne pathogens, but it is unclear which NLRs control endothelial cell (EC) intrinsic immunity. …”
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Data-driven approach to spatiotemporal dynamic risk assessment of urban flooding based on shared socio-economic pathways by Wang, Mo, Chen, Furong, Zhang, Dongqing, Chen, Zijing, Su, Jin, Zhou, Shiqi, Li, Jianjun, Chen, Jintang, Li, Jiaying, Tan, Soon Keat

“…Taking Guangdong Hong Kong Macao Greater Bay Area (GBA) as case study, the results showed that the increase in urban flooding was largely caused by the expansion of construction land. …”
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Organic and inorganic sublattice coupling in two-dimensional lead halide perovskites by Fu, Jianhui, Bian, Tieyuan, Yin, Jun, Feng, Minjun, Xu, Qiang, Wang, Yue, Sum, Tze Chien

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Local release of rapamycin by microparticles delays islet rejection within the anterior chamber of the eye by Fan, Yanliang, Zheng, Xiaofeng, Berggren, Per-Olof, Loo, Joachim Say Chye, Yusuf Ali

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The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8 activation in zebrafish photoreceptor outer segment formation and maintenance by Naharros, Irene Ojeda, Cristian, Flavia B., Zang, Jingjing, Gesemann, Matthias, Neuhauss, Stephan C. F., Bachmann-Gagescu, Ruxandra, Ingham, Philip William

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The iHealth-T2D study, prevention of type 2 diabetes amongst South Asians with central obesity and prediabetes: study protocol for a randomised controlled trial by Kasturiratne, Anuradhani, Khawaja, Khadija I., Ahmad, Sajjad, Siddiqui, Samreen, Shahzad, Khurram, Athauda, Lathika K., Jayawardena, Ranil, Mahmood, Sara, Muilwijk, Mirthe, Batool, Tayyaba, Burney, Saira, Glover, Matthew, Palaniswamy, Saranya, Bamunuarachchi, Vodathi, Panda, Manju, Madawanarachchi, Suren, Rai, Baldeesh, Sattar, Iqra, Silva, Wnurinham, Waghdhare, Swati, Jarvelin, Marjo-Riitta, Rannan-Eliya, Ravindra P., Gage, Heather M., van Valkengoed, Irene G. M., Valabhji, Jonathan, Frost, Gary S., Loh, Marie, Wickremasinghe, Ananda R., Kooner, Jaspal S., Katulanda, Prasad, Jha, Sujeet, Chambers, John C.

“…Based on the follow-up to end 2019, the observed incidence of T2D in the study population is in line with expectations (6.1% per annum). Conclusion: The iHealth-T2D study will advance understanding of strategies for the prevention of diabetes amongst South Asians, use approaches for screening and intervention that are adapted for low-resource settings. …”
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The need for pre-emptive control strategies for mpox in Asia and Oceania by Gan, Gregory, Janhavi, A., Tong, Guan, Lim, Jue Tao, Dickens, Borame L.

“…Materials and methods: Using data driven heterogeneous sexual contact networks, we simulated outbreaks of mpox in Singapore, Hong Kong, and Sydney. An individual based SEIR compartmental model was used to simulate epidemic trajectories and the impact of different vaccination uptakes was assessed in their ability to avert or suppress outbreaks upon the arrival of mpox within the MSM populations. …”
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High speed imaging of micro-sized droplet jetted on surface with wettability pattern by Lim, Chun Yee, Lam, Yee Cheong

“…Experimental results based on high speed imaging of micro-sized droplet jetted on a hydrophobic surface with hydrophilic lines are presented. The effects of the hydrophilic line and the initial impact offset distance from the line on the droplet spreading behaviour are studied. …”
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Population Balance Model-based Dynamic Multiobjective Optimization of Yeast Cell Manufacturing by Ganko, Krystian, Berliner, Marc D, Rhyu, Jinwook, Wu, Liang, Braatz, Richard D, Leyffer, Sven

“…Numerical optimal control design for oscillatory distributed parameter systems is discussed within the context of both dynamic optimization and on-line nonlinear model predictive control strategies.…”
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Productivity improvement for smart manufacturing systems by Sundararaman Manoj

“…On considering the improvements in manufacturing a product, this project aims to focus on developing a fundamental study that compares the infinite buffer and finite buffer settings for a production line and an assembly line. In an assembly line, queue ratio concept is introduced, that states, the parts from the upstream station is sent to two or more downstream stations for processing based on smallest queue ratio between two downstream stations. …”
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Roseburia intestinalis generated butyrate boosts anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8⁺ T cells by Kang, Xing, Liu, Changan, Ding, Yanqiang, Ni, Yunbi, Ji, Fenfen, Lau, Harry Cheuk Hay, Jiang, Lanping, Sung, Joseph Jao Yiu, Wong, Sunny Hei, Yu, Jun

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A smart way to wrap a building by Leng, Meiying, Long, Yi

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Time Tango by Pyae Thein

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Falling for Rachel / by Roberts, Nora, 1950- author 465662

“…Public defender Rachel Stanislaski is not what he has in mind—until he discovers there’s a lot more to the beautiful, coolheaded attorney than meets the eye…and finds himself falling for her, hook, line and sinker.…”

CASTERS OF EVERVILLE / by Yap, Cherilyn, author 655829, Ikram Wazir, editor 655732

“…Honey, his childhood friend, is determined to find a cure and put her life on the line in order to save her friend. With the entire town against Wyn, will there be enough time to save the people? …”

Effectiveness of product placements in computer games. by Chan, Jesslyn Hor Yee., Chua, Shi Wei., Lim, Chong Tat.

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GPS-based attitude determination and applications by Xia, Peiqing

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