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    Preparation, characterization and dermal delivery of methadone by Sil dos Santos, Bruno, Kung, Chin-Ping, Hadgraft, Jonathan, Lane, Majella E., Patel, Bhumik, McCulloch, Renée

    Published 2019
    “…In vitro permeation and mass balance studies were conducted under finite dose conditions (5 µL/cm2) in porcine skin. The results confirmed the more favorable penetration of methadone free base compared with the salt. …”
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