Simulations study of fluid-structure interaction of a wind turbine by Zheng, Shuai

“…This report presents the study of fluid-structure interaction (FSI) of a 5kW horizontal axis wind turbines (HAWT). The motivation of the current investigation is to address the FSI problem of HAWT in the whole flow field analysis with hybrid turbulence model method which is used to find out the flow and structure characteristics of wind turbine in operation under different tip speed ratio (TSR). …”
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Effect of educational intervention on the intention to provide family-centered care among selected hospitals’ paediatric nurses in Tehran, Iran by Rostami, Forouzan

“…The most significant predictor was attitude (β = 0.393, t =5.914, p < 0.01), followed by perceived behaviour control (β = 0.320, t = 4.815, p < 0.01) and subjective norms (β = 0.172, t = 2.184, p < 0.01). …”
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System-level design of low-carbon structures by Fang, Demi L.

“…“What is more likely to be associated with a reduction in emissions: switching from concrete to timber, or shortening the spans throughout the building?” …”
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Targeted hematopoietic stem cell depletion through SCF-blockade by Chan, Yan Y., Ho, Pui Y., Dib, Carla, Swartzrock, Leah, Rayburn, Maire, Willner, Hana, Ko, Ethan, Ho, Katie, Down, Julian D., Wilkinson, Adam C., Nakauchi, Hiro, Denis, Morgane, Cool, Taylor, Czechowicz, Agnieszka

“…Further, they highlight multiple approaches for efficacy in SCID settings and optimal combinations for WT settings. This work is likely to aid in the development of clinical non-genotoxic HSCT conditioning approaches that could benefit millions of people world-wide.…”
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Inclusions in calcite phantom crystals suggest role of clay minerals in dolomite formation by Farsang, Stefan, Pekker, Péter, Lampronti, Giulio I., Molnár, Zsombor, Milovský, Rastislav, Pósfai, Mihály, Ozdín, Daniel, Raub, Timothy D., Redfern, Simon Anthony Turner

“…While the micrometer-sized phyllosilicate and hematite particles were likely transported from the terra rossa and attached to the surface of growing calcite, the presence of phyllosilicates that are only a few atomic layers thick and of euhedral hematite, goethite, and dolomite crystals suggests that these particles precipitated along with the phantom calcite in situ, from an aqueous solution carrying terra rossa-derived and limestone-derived solutes. …”
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Aircraft noise, overheating and poor air quality in London primary schools' classrooms by Montazami, Azadeh

“…Through objective and subjective surveys, classrooms' indoor temperatures, air quality and background noise levels were evaluated and it was learnt that those schools located in the vicinity of Heathrow Airport are more likely to experience overheating and poor air quality. …”
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Preclinical development of antisense conjugates for the treatment of myotonic dystrophy 1 by Stoodley, J

“…It was concluded that this was likely due to the specific chemical properties of the compound rather than inherent limitations of anti-TfR1 antibodies, suggesting that further optimization of the conjugate’s chemical characteristics is necessary to improve therapeutic efficacy. …”

In situ metal organic framework (ZIF-8) and Mechanofusion-Assisted MWCNT coating of LiFePO4/C composite material for lithium-ion batteries by Mathur, Priyatrisha, Shih, Jengywan, James Li, Ying Jeng, Hung, Tai-Feng, Thirumalraj, Balamurugan, Kannan Ramaraj, Sayee, Jose, Rajan, Karuppiah, Chelladurai, Yang, Chunchen

“….% ZIF-8@LFP [A]/MWCNT composite cathode material exhibited outstanding improvement in high-rate performance; it maintained the discharge capacities of 125 mAh g−1 at 1C, 110 mAh g−1 at 3C, 103 mAh g−1 at 5C, and 91 mAh g−1 at 10C. Better cycling stability with capacity retention of 75.82% at 1C for 100 cycles, as compared to other electrodes prepared in this study, was also revealed. …”
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High sensitivity transparent glass ceramic systems development based on MgSO4:Dy2O3–B2O3 and MgSO4:Dy2O3–B2O3:ZnO:An investigation of FT-IR and thermal properties for thermolumines... by Naeem, Hayder Salah, Iskandar Shahrim, Mustafa, N. N., Yusof, Thabit, Hammam Abdurabu, Mhareb, M. H. A., Alajerami, Y. S. M., Raypah, Muna E., Mohd Noor, ., Shareef, Ammar Nadal, Khazaalah, Thair Hussein, Ezra, Nabasu Seth, Munirah, Jamil, Efenji, G. I., Muhammad Fadhirul Izwan, Abdul Malik

“…Two series of glass ceramics, [(MgSO4)86(Dy2O3)14]x[B2O3]1-x with x = 0.1, 0.2, 0.3, 0.4, 0.5 and [MgSO4-Dy2O3–B2O3]0·2[ZnO]x with x = 0.05, 0.1, 0.15, 0.2, were successfully prepared using the melt quenching technique. …”
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Surface peptide functionalization of zeolitic imidazolate framework-8 for autonomous homing and enhanced delivery of chemotherapeutic agent to lung tumor cells by Nurul Akmarina, Mohd Abdul Kamal, Emilia, Abdulmalek, Sharida, Fakurazi, Cordova, Kyle E., Mohd Basyaruddin, Abdul Rahman

“…Most importantly, this surface-functionalized nanoparticle was more selective towards lung cancer cells (A549) than normal human lung fibroblast cells (MRC-5) with a selectivity index (SI) of 3.98. This work demonstrates a new one-pot strategy for realizing a surface-functionalized zeolitic imidazolate framework that actively targets cancer cells via an autonomous homing peptide system to deliver a chemotherapeutic payload effectively.…”
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Dissolution and biological assessment of cancer-targeting nano-ZIF-8 in zebrafish embryos by Nurul Akmarina, Mohd Abdul Kamal, Emilia, Abdulmalek, Sharida, Fakurazi, Cordova, Kyle E.

“…Monitoring malformation showed minimal adverse effects with only 8.3% of edema at 62.5 μg mL–1. This study indicates that cancer-targeting GEM⊂RGD@nZIF, with its pH-responsive behavior for sustaining chemotherapeutic dissolution in a physiologically relevant environment and its non-toxicity toward the healthy embryos within the tested concentrations, has considerable potential for use in cancer treatment.…”
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Integrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture System by Large, Emma, Hughes, David J., Sarkar, Ujjal, Ravindra, Kodihalli C., Young, Carissa L., Rivera-Burgos, Dinelia, Yu, Jiajie, Cirit, Murat, Wishnok, John S, Lauffenburger, Douglas A, Griffith, Linda G, Tannenbaum, Steven R

“…Kupffer cell–mediated cytokine release recapitulated an in vivo proinflammatory response exemplified by a cohort of 11 cytokines that were differentially regulated after lipopolysaccharide induction, including interleukin (IL)-1β, IL-1Ra, IL-6, IL-8, IP-10, tumor necrosis factor-α, RANTES (regulated on activation normal T cell expressed and secreted), granulocyte colony-stimulating factor, macrophage colony-stimulating factor, macrophage inflammatory protein-1β, and IL-5. In summary, our findings indicate that three-dimensional liver microphysiological systems may serve as preclinical investigational platforms from the perspective of the discovery of a set of clinically relevant biomarkers including potential reactive metabolites, endogenous bile acids, excreted proteins, and cytokines to predict early drug-induced liver toxicity in humans.…”
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Study of $$ {B}_c^{+}\to {\chi}_c{\pi}^{+} $$ decays by Aaij, R., Abdelmotteleb, A. S. W., Abellan Beteta, C., Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F.

“…A study of B c + → χ c π + $$ {B}_c^{+}\to {\chi}_c{\pi}^{+} $$ decays is reported using proton-proton collision data, collected with the LHCb detector at centre-of-mass energies of 7, 8, and 13 TeV, corresponding to an integrated luminosity of 9 fb−1. …”
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Efficient and Homogenous Precipitation of Sulfur Within a 3D Electrospun Heterocatalytic Rutile/Anatase TiO2-x Framework in Lithium–Sulfur Batteries by Feng, Ping, Dong, Kang, Xu, Yaolin, Zhang, Xia, Jia, Haojun, Prell, Henrik, Tovar, Michael, Manke, Ingo, Liu, Fuyao, Xiang, Hengxue, Zhu, Meifang, Lu, Yan

“…As a result of these advantageous features, the TiO2-x/CNFs-based cathode demonstrates an initial specific discharge capacity of 787.4 mAh g−1 at 0.5 C in the Li–S coin cells, and a final specific discharge capacity of 584.0 mAh g−1 after 300 cycles. …”
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State and Dynamics Estimation in an Outdoor Multi-Drone Slung Load System by Merton, Harvey

“…Real world testing shows errors of 0.2 m and 5 ◦ respectively. Applying extended Kalman filter and unscented Kalman filter formulations, simulated position estimates average around an error of 0 m, while the error noise magnitude is only 6% of the cable length at 0.06 m. …”
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Synthesis of α-methylene-δ-valerolactone and its selective polymerization from a product mixture for concurrent separation and polymer production by Khechfe, Alexander A, Eckstrom, Francesca D, Chokkapu, Eswara Rao, Baston, Lucas A, Liu, Bowei, Chen, Eugene Y-X, Román-Leshkov, Yuriy

“…MgO, CaO, and BaO supported on silica (∼5 wt%) were active for MVL production (613 K, 0.4 kPa DVL, 1.2 kPa FA, 101 kPa total pressure). …”
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Cooperation and Fairness in Multi-Agent Reinforcement Learning by Aloor, Jasmine, Nayak, Siddharth Nagar, Dolan, Sydney, Balakrishnan, Hamsa

“…For goal coverage scenarios, we find that, on average, the proposed model yields a 14% improvement in efficiency and a 5% improvement in fairness over a baseline model that is trained using random assignments. …”
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An encoding scheme capturing generic priors and properties of amino acids improves protein classification by Zhou, Xinrui, Yin, Rui, Zheng, Jie, Kwoh, Chee-Keong

“…Compared with the traditional methods using task-specific designed features, CFreeEnS improves the predicting accuracy, with an increase ranging from 5.54% to 14.14%. The results indicate that the improved CFreeEnS, free from dependence on carefully designed features, is promising in capturing generic priors and essential properties of amino acids, thereby serving as an automated feature engineering method for protein sequences.…”
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Scaffold-mediated non-viral delivery platform for CRISPR/Cas9-based genome editing by Chin, Jiah Shin, Chooi, Wai Hon, Wang, Hongxia, Ong, William, Leong, Kam W., Chew, Sing Yian

“…To evaluate the genome-editing efficiency of this platform, U2OS.EGFP cells were used as the model cell type. pDOPA coating was essential in allowing Cas9:sgRNA lipofectamine complexes to adhere onto the scaffolds with a higher loading efficiency, while laminin coating was necessary for maintaining cell viability and proliferation on the pDOPA-coated fibers for effective gene editing (21.5% editing efficiency, p < 0.001). Importantly, U2OS.EGFP cells took up Cas9:sgRNA lipofectamine complexes directly from the scaffolds via reverse transfection. …”
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Africa Digest : Trends and issues in business Vol. 18 by Burger, Johan

“…This report addresses developments on the involvement of countries from the Middle East in Africa. 5. Developments for MTN, Africa’s largest telecoms company - MTN Group is Africa’s largest telecoms company. …”
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