Roseburia intestinalis generated butyrate boosts anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8⁺ T cells by Kang, Xing, Liu, Changan, Ding, Yanqiang, Ni, Yunbi, Ji, Fenfen, Lau, Harry Cheuk Hay, Jiang, Lanping, Sung, Joseph Jao Yiu, Wong, Sunny Hei, Yu, Jun

“…R. intestinalis administration significantly inhibited tumour formation in Apc(Min/+) mice, which was confirmed in mice with AOM-induced CRC. …”
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Design, synthesis and activity studies of antifreeze peptide derived from type I shorthorn sculpin by Asmawi, Azren Aida

“…Freezing water is rapidly fatal to most organisms as it deprives biological reactions of the aqueous medium they require due to the formation of ice crystals. However, a number of structurally different classes of antifreeze proteins (AFPs) allow cold-adapted organisms to survive in a sub-zero environment by inhibiting the growth of the ice crystals; phenomenon’s known as Thermal Hysteresis (TH) and Ice Recrystallization Inhibition (IRI). …”
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Negative auto-regulation of myostatin expression is mediated by SMAD3 and microRNA-27 by Ge, XiaoJia, McFarlane, Craig, Vajjala, Anuradha, Arigela, Harikumar, Lokireddy, Sudarsanareddy, Bonala, Sabeera, Manickam, Ravikumar, Kambadur, Ravi, Sharma, Mridula

“…Sequence analysis of Mstn 3′ UTR showed a single highly conserved miR-27a/b binding site and increased expression of miR-27a/b was correlated with decreased expression of Mstn and vice versa both in vitro and in mice in vivo. Moreover, we also show that Mstn gene expression was regulated by miR-27a/b. …”
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Temporal and spatial characteristics of the Beaufort Sea ambient noise environment by Chen, R., Schmidt, H.

“…The discrete ranges to this ice activity explain the peak arrival angles between −10 to −15 degrees in noise vertical directionality, as well as the horizontal noise notch. …”
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Motion control (brushless DC motor) of a lower limb robotic orthosis for rehabilitation of stroke and incomplete SCI patients by Lim, Zhenhui

“…Strokes and spinal cord injuries (SCI) can cause motor malfunction to the patients resulting in the loss of the ability to walk. …”
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Immunotherapy-responsive neuropathic pain and allodynia in a patient with glycine receptor autoantibodies: a case report by Soleimani, B, Board, C, Yu, T, Tracey, I, Irani, SR, Foley, P

“…Glycine receptors are known to play a key role in inhibitory neurotransmission in the spinal dorsal horn and have therefore been considered as targets for analgesic development. …”

Structural investigation, computational analysis, and theoretical cryoprotectant approach of antifreeze protein type IV mutants by Eskandari, Azadeh, Leow, Thean Chor, Abdul Rahman, Mohd Basyaruddin, Oslan, Siti Nurbaya

“…Antifreeze proteins (AFPs) have unique features to sustain life in sub-zero environments due to ice recrystallization inhibition (IRI) and thermal hysteresis (TH). …”

Spectroscopic study of emergent electronic phases in transition metal based compounds by Song, Qian

“…Antiferromagnets with non-relativistic spin splitting are outstanding candidates as the next generation of spintronic materials owing to their electron-volt (eV) scale spin splitting, ultrafast spin dynamics and nearly vanishing stray fields. …”
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Holocene relative sea-level histories of tropical islands by Tan, Fangyi

“…In particular, RSL changes in tropical locations distal from the deglaciation centres of past ice sheets are sensitive to the input of meltwater into the oceans (otherwise known as ‘ice-equivalent sea-level changes’). …”
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Organic donor-acceptor cocrystals for multiferroic applications by Wang, Zongrui, Zhang, Qichun

“…The cocrystallization strategy has provided an efficient route to fulfill room temperature magnetoelectricity in single phase owing to the long-range ordered π-π stacking (donor-acceptor assembled) network, long-lived excitons (with μs lifetime), spin orders (±1/2 s pin) and charge transfer (CT) dipoles in the assembled crystal lattice. …”
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Distinct movement disorders in contactin-associated-protein-like-2 antibody-associated autoimmune encephalitis by Gövert, F, Abrante, L, Becktepe, J, Balint, B, Ganos, C, Hofstadt-van Oy, U, Krogias, C, Varley, J, Irani, SR, Paneva, S, Titulaer, MJ, de Vries, JM, Boon, AJW, Schreurs, MWJ, Joubert, B, Honnorat, J, Vogrig, A, Ariño, H, Sabater, L, Dalmau, J, Scotton, S, Jacob, S, Melzer, N, Bien, CG, Geis, C, Lewerenz, J, Prüss, H, Wandinger, K-P, Deuschl, G, Leypoldt, F

“…Further distinct movement disorders include isolated and combined segmental spinal myoclonus and autoimmune episodic ataxia.</p>…”

Characterization of cell types and connectivity of the deep cerebellar nuclei by Lim, Zoe Hui

“…Taken together, our results indicate that direct projections from the cerebellum to hippocampus and hypothalamus exist in mice and we have begun to characterize the cells from which these connections may arise.…”
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Stress faced by executives in Singapore. by Par, Hwee Fong., Tan, Chin Ying., Thong, Hwei Ling.

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Challenges faced by women in the corporate world by Ang, Hui Jia, Sim, Jasmine Mei Yao, Yeo, Siew Hong

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Quantifying the internal and external drivers of Southeast Asian rainfall extremes on decadal timescales by Wang, Shouyi, Ummenhofer, Caroline C., Murty, Sujata A., Nguyen, Hung T. T., Buckley, Brendan M.

“…Volcanic aerosols, the most effective radiative forcing during the last millennium, contributed to both the Ming Dynasty Drought (1637–1643) and the Strange Parallels Drought (1756–1768). …”
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Fabrication of heat sinks by Selective Laser Melting for convective heat transfer applications by Wong, Kin Keong, Ho, Jin Yao, Leong, Kai Choong, Wong, Teck Neng

“…Three heat sinks comprising pin fins of circular, rectangular-rounded and aerofoil geometries were fabricated by SLM from aluminium alloy AlSi10Mg powder. …”
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Comparative study of accounting standards between Singapore and the Peoples' Republic of China by Neo, Karn Nee, Siew, May San, Swi, Li Li

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Behavioural and biochemical abnormalities in a mouse model for Parkinson's disease. by Ten, Rachel Rui Xian.

“…There were no statistical differences in anxiety and depression-like behaviour between the non-transgenic and transgenic mice. These results were concomitant with good motor performance in both mice groups, though, contrary to published literature, motor deficits were not found in older (6 months old) mice. …”
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Engineered terahertz emission from spintronic heterostructures: amplitude, phase and chirality by Agarwal, Piyush

“…As such, the photoexcitation leads to ultrafast spin-scattering events in the FM, during which the spins transport from the FM into the adjacent heavy metal(HM) layer to experience an inverse spin Hall effect, producing a transverse charge current and terahertz radiation. …”
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Convective boiling and condensation in enhanced tubes produced by selective laser melting by Tan, Choon Yong

“…The design of the four tubes are five long circumferential pin fins, eight short circumferential pin fins, twisted pin fins and a metallic foam structure. …”
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