Report to the President for year ended June 30, 2022, Arts Initiatives by Kinney, Leila W.

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Time-restricted feeding modulates the DNA methylation landscape, attenuates hallmark neuropathology and cognitive impairment in a mouse model of vascular dementia by Selvaraji, Sharmelee, Efthymios, Motakis, Foo, Roger Sik Yin, Fann, David Y., Lai, Mitchell Kim Peng, Chen, Christopher Li Hsian, Lim, Kah-Leong, Arumugam, Thiruma V.

“…Modulation of DNA methylation patterns in the cortex of AL CCH mice was re-modelled and signs of reversal was observed in IF CCH mice across all three timepoints. …”
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Homocysteine metabolism pathway is involved in the control of glucose homeostasis: a cystathionine beta synthase deficiency study in mouse by Cruciani-Guglielmacci, Céline, Meneyrol, Kelly, Denom, Jessica, Kassis, Nadim, Rachdi, Latif, Makaci, Fatna, Migrenne-Li, Stéphanie, Daubigney, Fabrice, Georgiadou, Eleni, Denis, Raphaël G., Sanchez-Archidona, Ana Rodriguez, Paul, Jean-Louis, Thorens, Bernard, Rutter, Guy A., Magnan, Christophe, Le Stunff, Hervé, Janel, Nathalie

“…We evidenced a defect in the stimulated insulin secretion in CBS+/- mice with mild and intermediate HHcy, while mice with intermediate HHcy under HFD presented an improvement in insulin sensitivity that compensated for the decreased insulin secretion and permitted them to maintain a glucose tolerance similar to the CBS+/+ mice. …”
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Characterizing the function of the Arl15 gene and its role in the development of metabolic traits by Bai, Y

“…</p> <p>CRISPR/Cas9 germline knockout of Arl15 showed that homozygous KO mice die postnatally due to a complete cleft palate while heterozygous KO female mice have reduced fat mass on a normal diet. …”

Classification of helicopters for passive radar - theoretical studies and measurements by Qiao, Na

“…Instead of testing using stimulating blades, we testing an air fan in the north spine campus to see if interference exist whether will affect our result.…”
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Telomere oxidation status (TOS) is correlated with relative telomere length (RTL) across different mouse tissues but not with nicotinamide nucleotide transhydrogenase (Nnt) status by Kidd, Elliot, Meimaridou, Eirini, Walley, Andrew, Fairbrother, Una

“…We investigated whether Nnt deficient mice have reduced TL and display markers of TOS compared to WT and rescued mice and whether this was tissue specific.…”
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Mobile app to play team-building games by Liao, Qian Ping

“…This project documents the design and implementation of the game application Break The Ice. Break The Ice features a puzzle game with rotating puzzle pieces, and players in the team must rotate the puzzle pieces back to their original orientation to complete the game. …”
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Direct observation of deterministic domain wall trajectory in magnetic network structures by Sethi, Pankaj, Murapaka, Chandrasekhar, Goolaup, Sarjoosing, Chen, Yun Jie, Leong, Siang Huei, Lew, Wen Siang

“…The DW propagation in the network structure is governed by the geometrically induced potential barrier and pinning strength against the propagation. This technique can be extended for controlling the trajectory of magnetic charge carriers in an artificial spin ice lattice.…”
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Automatic test chip set by Chin, Edward Hsi Ling.

“…In this project, the fundamental functions and basic circuitry of an universal pin electronics are investigated and designed.…”
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Loss of caveolin-1 impairs light flicker-induced neurovascular coupling at the optic nerve head by Loo, Jing Hong, Lee, Ying Shi, Woon, Chang Yi, Yong, Victor H. K., Tan, Bingyao, Schmetterer, Leopold, Chong, Rachel S.

“…Cav-1 KO mice exhibited higher IOP and lower pSTR amplitude. …”
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Anti-leukaemic and chemotherapy supportive effects of berberis vulgaris l. Fruit crude extract on in vitro and in vivo models by Saedi, Tayebeh Azam

“…In contrast, the amount of WBC decreased dramatically in mice treated with BVFCE, and doxorubicin compared to the mice group without treatment, which showed a high number of leukaemic cells. …”
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A 1-bit 16×16 reconfigurable intelligent surfaces array for C-band by Zhang, Yucheng

“…RIS array is achieved by combining a number of basic elements together with PIN diodes which control the on and off state of RIS units. …”
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Behind every domain there is a shift: adapting distortion-aware vision transformers for panoramic semantic segmentation by Zhang, J, Yang, K, Shi, H, ReiB, S, Peng, K, Ma, C, Fu, H, Torr, PHS, Wang, K, Stiefelhagen, R

“…Third, aside from Pinhole-to-Panoramic ( Pin2Pan ) adaptation, we create a new dataset (SynPASS) with 9,080 panoramic images, facilitating Synthetic-to-Real ( Syn2Real ) adaptation scheme in 360∘&nbsp;imagery. …”

Exploring the induction of preproinsulin-specific Foxp3+ CD4+ Treg cells that inhibit CD8+ T cell-mediated autoimmune diabetes by DNA vaccination by Stifter, Katja, Schuster, Cornelia, Schlosser, Michael, Boehm, Bernhard Otto, Schirmbeck, Reinhold

“…TGF-β expression was significantly enhanced in the Foxp3(+) CD25(+) Treg cell population of vaccinated/ppins-primed mice. Ablation of Treg cells in vaccinated/ppins-primed mice by anti-CD25 antibody treatment abolished the protective effect of the vaccine and enabled diabetes induction by pCI/ppins. …”
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Reverse translational approaches to population neuroimaging: using rodent models to interpret genetic associations with MRI by Tisca, C

“…The genetic similarity between humans and mice means we can measure and compare equivalent phenotypes across species. …”

Dysfunctional cardiac energy transduction, mitochondrial oxidative stress, oncogenic and apoptotic signaling in DiNP-induced asthma in murine model by Kehinde, Samuel Abiodun, Olajide, Abosede Temitope, Fatokun, Tolulope Peter, Faroud, Dalia, Hadi, Najah R., Elgazzar, Ahmed M., James, Adewale Segun, Ashour, Mohamed H. Mazhar

“…In the current study, we assessed the crosstalk between DiNP-induced asthma and cardiac cellular respiration, oxidative stress, apoptotic potential, and induction of oncogenic factors. Ten male BALB/c mice with a weight range of 20–30 g were divided into two groups, each comprising five mice. …”
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The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator by Wong, Brandon Han Siang, Shim, Heesung, Goay, Stephanie Shee Min, Ong, Seow Theng, Nur Ayuni Binte Muhammad Taib, Chai, Kelila Xin Ye, Lim, Kerry, Huang, Dachuan, Ong, Choon Kiat, Vaiyapuri, Thamil Selvan, Cheah, Yeong Cheng, Wang, Yulan, Wulff, Heike, Webster, Richard David, Shelat, Vishalkumar G., Verma, Navin Kumar

“…SKA-346 (30 mg kg-1), tolerated by mice after intra-peritoneal administration, exhibited a peak plasma concentration of 6.29 μg mL-1 (29.2 μM) at 15 min and a circulating half-life (t 1/2) of 2.8 h. …”
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Determination of the life span of inflammatory dendritic cells by Tay, Yong Long

“…Due to the lack of a proper Plet-1 knockout mice model previously, cell ablation study of Plet-1+ DCs was not possible. …”
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Experimental studies of melting PCM in a heat sink by Muhammad Azrin Sa'ad.

“…The heat sink design that was the focus of this study is based on the pin finned heat sink design. Experiments mainly pertaining to the characteristics of the melting PCM in the heat sinks were observed and recorded to further understand the behaviours and characteristics of the melting PCM. …”
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Songs of The Runaway Heart / by Marisa Fendi, author 655832

“…Despite their fathers’ bond over wealth and luxuries, Kamelia and Haikal’s bond was made up of glares and stolen ice pops. But one day, everything stopped. The banter, the bag-tugging, the eye-rolling. …”