In vivo visualization of cells with fluorescent-labeled fab fragment. by Wee, Armanda Lixuan.

“…However, the current use of fluorescent reporter mice and fluorescent-labeled antibodies are accompanied with several limitations that restricts their usefulness for in vivo imaging. …”
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Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome by Alford, KA, Slender, A, Vanes, L, Li, Z, Fisher, EMC, Nizetic, D, Orkin, SH, Roberts, I, Tybulewicz, VLJ

“…We show that although Tc1 mice do not develop leukemia, they have macrocytic anemia and increased extramedullary hematopoiesis. …”

Wearable bio-adhesive metal detector array (BioMDA) for spinal implants

“…Accordingly, herein, we report on the development and engineering of a bio-adhesive metal detector array (BioMDA), a potential wearable solution for real-time, non-invasive positional analyses of osseous implants within the spine. The electromagnetic coupling mechanism and intimate interfacial adhesion enable the precise sensing of the metallic implants position without the use of radiation. …”
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Deep learning approach to cervical segmentation from routine CT images by Duan, Yiming

“…To address the sequential and location-dependent nature of bone segmen tation information, the dissertation proposes a pre-training model for location information, and combines 2.5D image input and labeled multi-channel coding to semantically segment 3D cervical spine CT images. This method can accu rately extract the information of bone joint location of slices and incorporate it into image features in the form of channels, which can improve the accuracy of multiple bone joint segmentation and classification. …”
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Measuring membrane capacitance during a depolarizing stimulus by Chen, Peng., Gillis, Kevin., Xue, Renhao., Pui, Tze Sian.

“…It is critical to resolve the highly dynamic kinetic steps along the molecular cascade of exocytosis in order to pin down the specific actions of regulatory molecules and eventually decipher this complex and fundamental process.…”
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Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and is Activated by PPARβ/δ Deficiency by Zarei, Mohammad, Barroso, Emma, Leiva, Rosana, Barniol-Xicota, Marta, Pujol, Eugènia, Escolano, Carmen, Vázquez, Santiago, Palomer, Xavier, Pardo, Virginia, González-Rodríguez, Águeda, Valverde, Ángela M., Quesada-López, Tania, Villarroya, Francesc, Wahli, Walter, Vázquez-Carrera, Manuel

“…Increased Fgf21 expression was observed in liver of PPARβ/δ-null mice and in mouse primary hepatocytes when this receptor was knocked down by small interfering RNA (siRNA). …”
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The role of calcium dependent neurotransmission in axon path finding, myelination and maintenance of specified cortical projection neuron populations by Korrell, K

“…</p> <p>Together, the results indicate that neuronal activity has little effect on the onset of myelination but has effects on the g-ratio in deep cortical layer projection neurons in mice.</p>…”

Synaptic CMOS transistor by Chai, Zhen Hong

“…In this work, electrical measurements were conducted on commercial level TiN/HfO2 gated n-channel MOSFET transistor (with an equivalent oxide thickness of 1.7nm) to demonstrate that it can exhibit some critical synaptic characteristics of a biological synapse such as excitatory and inhibitory postsynaptic current (EPSC and IPSC), short-term plasticity (STP) and long-term potentiation (LTP), metaplasticity, and spike timing dependent plasticity (STDP). The mechanism behind the output characteristic of MOSFET to exhibit synaptic-like response is the charge trapping and de-trapping at defects in the oxide and oxide/semiconductor interface. …”
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A scalable variational inference approach for increased mixed-model association power by Loya, H, Kalantzis, G, Cooper, F, Palamara, PF

“…We developed Quickdraws, a method that increases association power in quantitative and binary traits without sacrificing computational efficiency, leveraging a spike-and-slab prior on variant effects, stochastic variational inference and graphics processing unit acceleration. …”

Indoor localization using Wi-Fi by Siswanto, Hadi

“…All models are evaluated using data collected from several reference points on block N4, North Spine, Nanyang Technological University. A simple Android application is developed to assist data collection. …”
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Development of a counter-UAV system by Tang, Wen Yue

“…Upon testing, the firing pin mechanism was found to be unable to reliably puncture the CO2 canister, even after improvements. …”
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Mass spectrometry imaging highlights dynamic patterns of lipid co-expression with Aβ plaques in mouse and human brains by Huang, Helen Xuexia, Inglese, Paolo, Tang, Jiabin, Yagoubi, Riad, Correia, Gonçalo D. S., Horneffer-van der Sluis, Verena M., Camuzeaux, Stephane, Wu, Vincen, Kopanitsa, Maksym V., Willumsen, Nanet, Jackson, Johanna S., Barron, Anna M., Saito, Takashi, Saido, Takaomi C., Gentlemen, Steve, Takats, Zoltan, Matthews, Paul M.

“…To delineate the pathological correlations of distinct lipid species, we conducted a comprehensive characterization of both spatially localized and global differences in brain lipid composition in AppNL-G-F mice with spatial and bulk mass spectrometry lipidomic profiling, using human amyloid-expressing (h-Aβ) and WT mouse brains controls. …”
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Enhanced restoration of visual code after targeting ON bipolar cells compared to retinal ganglion cells with optogenetic therapy by Rogers, J, Hughes, S, Ebrahimi, A, Allen, A, Storchi, R, Lindner, M, Peirson, S, Badea, T, Hankins, M, Lucas, R

“…Our data show that, while both approaches restore visual responses with impressive fidelity, ON BC targeting produces a richer visual code closer to that of wild-type mice. …”

Strong immune responses and robust protection following a novel protein in adjuvant tuberculosis vaccine candidate by Korompis, M, De Voss, CJ, Li, S, Richard, A, Almujri, SS, Ateere, A, Frank, G, Lemoine, C, McShane, H, Stylianou, E

“…Vaccinated mice had enriched lung parenchymal antigen-specific CD4 + CXCR3 + KLRG1− T cells previously associated with TB protection. …”

Lessons from a retrospective look at India’s upstream sector by Elango, P

Mitofusins Mfn1 and Mfn2 are required to preserve glucose- but not incretin-stimulated β-cell connectivity and insulin secretion by Georgiadou, Eleni, Muralidharan, Charanya, Martinez, Michelle, Chabosseau, Pauline, Akalestou, Elina, Tomas, Alejandra, Yong, Fiona Su Wern, Stylianides, Theodoros, Wretlind, Asger, Legido-Quigley, Cristina, Jones, Ben, Lopez-Noriega, Livia, Xu, Yanwen, Gu, Guoqiang, Alsabeeh, Nour, Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Ali, Yusuf, Soleimanpour, Scott A., Linnemann, Amelia K., Rodriguez, Tristan A., Rutter, Guy A.

“…Whether mitofusin gene expression, and hence, mitochondrial network integrity, is important for glucose or incretin signaling has not previously been explored. Here, we generated mice with β-cell-selective, adult-restricted deletion knock-out (dKO) of the mitofusin genes Mfn1 and Mfn2 (βMfn1/2 dKO). βMfn1/2-dKO mice displayed elevated fed and fasted glycemia and a more than fivefold decrease in plasma insulin. …”
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Dengue death rate higher among women than men in Bangladesh by Roney, Miah, Mohd Fadhlizil Fasihi, Mohd Aluwi

“…Given the atypical seasonality of the epidemic and the sudden spike in cases early on, it is noteworthy that mosquito and potential hotspot densities were at an all-time high throughout the previous years.…”
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Design and development of extreme learning machine symposium web portal by Chiang, Yu Hui.

“…In recent years, it has been observed that there is a spike in interest in the development of web based conference management systems. …”
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Mean-field approximation for networks with synchrony-driven adaptive coupling by Fennelly, N, Neff, A, Lambiotte, R, Keane, A, Byrne, A

“…In place of the less tractable spike-timing-dependent plasticity, we employ recently validated phase-difference-dependent plasticity rules, which adjust coupling strengths based on the relative phases of θ-neuron oscillators. …”

中朝古代桃花源文学比较研究 = A comparative study of peach blossom literature in ancient China and Korea by 蔡佳敏 Cai, Jiamin

“…This peach blossom imagery develops from Tao Yuan Ming's portrayal of a peach blossom in his famous poetry "The Peach Colony" ("Tao Hua Yuan Shi with Ji"). …”
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