A two-dimensional co-rotational Timoshenko beam element with XFEM formulation by Xu, Jin, Lee, Chi King, Tan, Kang Hai

“…Pin connections and plastic hinges produce non-smooth displacement fields in beam structures. …”
Get full text
Get full text

Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging by Baik, Sang-Ha, Selvaraji, Sharmelee, Fann, David Y., Poh, Luting, Jo, Dong-Gyu, Herr, Deron R., Zhang, Shenpeng R., Kim, Hyun Ah, Silva, Michael De, Lai, Mitchell K. P., Chen, Christopher Li- Hsian, Drummond, Grant R., Lim, Kah-Leong, Sobey, Christopher G., Arumugam, Thiruma V.

“…However, BCAS-induced changes in hippocampal gene expression differed between young and aged mice. Specifically, transcriptomic analysis indicated that in comparison to young sham mice, many pathways altered by BCAS in young mice resembled those already present in sham aged mice. …”
Get full text

In vitro and In vivo photothermal cancer therapeutic effects of gold nanorods modified with mushroom β-glucan by Li, Xiaojie, Zhou, Jiajing, Dong, Xiaonan, Cheng, Wai-Yin, Duan, Hongwei, Cheung, Peter C. K.

“…Intravenous injection of AuNR-Glu nanohybrids followed by irradiation from a NIR-II laser at a safe dose (1.0 W/cm2 for 5 min) in nude mice implanted with HT-29 tumors was effective in significantly reducing the tumor growth, with no obvious harmful side effects, as evidenced by histological analysis of major organs. …”
Get full text

Evaluation of the Digital Ventilated Cage® system for circadian phenotyping by Tir, S, Foster, RG, Peirson, SN

“…Home cage activity in C57BL/6J mice was recorded under a range of lighting conditions, along with circadian clock-deficient cryptochrome-deficient mice (Cry1−/−, Cry2−/− double knockout). …”

Study of heat transfer through micro-structured surfaces by Chin, Wei Hao

“…Each chip has a different microstructure in the form of very small and elongated pin-fins, which will in turn affect the critical heat flux of each component. …”
Get full text

Home by Pei, Qianru

Get full text

Metronidazole causes skeletal muscle atrophy and modulates muscle chronometabolism by Manickam, Ravikumar, Oh, Hui Yun Penny, Tan, Chek Kun, Paramalingam, Eeswari, Wahli, Walter

“…Furthermore, metronidazole in SPF mice decreases hind limb muscle weight and results in smaller fibers in the tibialis anterior muscle. …”
Get full text
Get full text

Quantifying the permeability reduction of biogrouted rock fracture by Wu, Chuangzhou, Chu, Jian, Wu, Shifan, Guo, Wei

“…However, the viscosity of cement grout is high and the particle sizes may not be fine enough to penetrate through fine rock joints. …”
Get full text

Obesity-driven reprogramming of lung macrophages by Pohan, Clarice

“…Upon further investigation, we found that AMs from high-fat diet fed obese (>30wks) mice had larger lipid droplets than those from young lean (<12wks) and age-matched lean (>30wks) mice. …”
Get full text

PIERCE1: a determinant of left-right asymmetry in mammals by Farley, H

“…<p>The study of mice with heart and situs defects can provide useful models for improving our understanding of congenital heart defects in humans. …”

Local release of rapamycin by microparticles delays islet rejection within the anterior chamber of the eye by Fan, Yanliang, Zheng, Xiaofeng, Berggren, Per-Olof, Loo, Joachim Say Chye, Yusuf Ali

“…Here, we show that islet rejection in the ACE of mice can be significantly suppressed through local delivery of rapamycin by carefully designed sustained-release microparticles. …”
Get full text
Get full text

Build-A-Bae : interrogating female stereotypes in Singapore by Ming Rui, Lee

Get full text

Study of bioheat transfer and cardiac thermal pulse of aneurysm in the abdominal aortic using computational fluid dynamic and fluid structure interaction by Looi, Jun Cong

“…Besides, from CFD rigid-body and FSI Analysis, the bioheat transfer effect resulted in a circular thermal elevation on the temperature profile of midriff skin surface patient, at both regular body temperature and supine position, under normal clinical temperature. …”
Get full text

Cortical regulation of sleep by Krone, LB

“…First, I present laminar recordings of neocortical activity during sleep in wild type mice, which suggest that layer 5 actively drives slow waves. …”

Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors by Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole

“…KI mice expressing functional human BCRs promise to accelerate the development of vaccines for HIV and other infectious diseases.…”
Get full text

Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis by Alvarez-Martinez, M, Cox, LS, Pearson, CF, Branchett, WJ, Chakravarty, P, Wu, X, Slawinski, H, Al-Dibouni, A, Samelis, VA, Gabryšová, L, Priestnall, SL, Suárez-Bonnet, A, Mikolajczak, A, Briscoe, J, Powrie, F, O'Garra, A

“…Double-deficient Prdm1^fl/flMaf^fl/flCd4^Cre mice infected with Helicobacter hepaticus developed severe colitis with an increase in T_H1/NK/ILC1 effector genes in LPLs, while Prdm1^fl/flCd4^Cre and Maf^fl/flCd4^Cre mice exhibited moderate pathology and a less-marked type 1 effector response. …”

Cyanographene and graphene acid : the functional group of graphene derivative determines the application in electrochemical sensing and capacitors by Cheong, Yi Heng, Muhammad Zafir Mohamad Nasir, Bakandritsos, Aristides, Pykal, Martin, Jakubec, Petr, Zbořil, Radek, Otyepka, Michal, Pumera, Martin

“…Well‐defined, stoichiometric derivatives of graphene afford many opportunities in fine‐tuning of graphene properties and hence, extend the application potential of this material. …”
Get full text

Design of wideband low-loss reconfigurable reflectarray antenna by Zhang, Xiran

“…It proposes an RRA design that integrates a PIN diode with air gap. The switch of the reconfigurable unit is directly mounted on the reflective element, reducing the loss introduced by the switching device. …”
Get full text

Evaluating new malaria vaccine candidates by Noé, A

“…In a human efficacy study of prime-target vaccination, multi-omic analyses were performed on hepatic fine needle aspirates and peripheral blood samples to study liver TRM and their circulating counterparts. …”

Development of optical transceiver by Sim, Sebastian Shih Wei.

“…For PIN photodiodes, the epitaxial layer was introduced to the structures to act as an intrinsic layer. …”
Get full text