In vitro and In vivo photothermal cancer therapeutic effects of gold nanorods modified with mushroom β-glucan by Li, Xiaojie, Zhou, Jiajing, Dong, Xiaonan, Cheng, Wai-Yin, Duan, Hongwei, Cheung, Peter C. K.

“…Intravenous injection of AuNR-Glu nanohybrids followed by irradiation from a NIR-II laser at a safe dose (1.0 W/cm2 for 5 min) in nude mice implanted with HT-29 tumors was effective in significantly reducing the tumor growth, with no obvious harmful side effects, as evidenced by histological analysis of major organs. …”
Get full text

Evaluation of the Digital Ventilated Cage® system for circadian phenotyping by Tir, S, Foster, RG, Peirson, SN

“…Home cage activity in C57BL/6J mice was recorded under a range of lighting conditions, along with circadian clock-deficient cryptochrome-deficient mice (Cry1−/−, Cry2−/− double knockout). …”

Study of heat transfer through micro-structured surfaces by Chin, Wei Hao

“…Each chip has a different microstructure in the form of very small and elongated pin-fins, which will in turn affect the critical heat flux of each component. …”
Get full text

Home by Pei, Qianru

Get full text

Metronidazole causes skeletal muscle atrophy and modulates muscle chronometabolism by Manickam, Ravikumar, Oh, Hui Yun Penny, Tan, Chek Kun, Paramalingam, Eeswari, Wahli, Walter

“…Furthermore, metronidazole in SPF mice decreases hind limb muscle weight and results in smaller fibers in the tibialis anterior muscle. …”
Get full text
Get full text

Quantifying the permeability reduction of biogrouted rock fracture by Wu, Chuangzhou, Chu, Jian, Wu, Shifan, Guo, Wei

“…However, the viscosity of cement grout is high and the particle sizes may not be fine enough to penetrate through fine rock joints. …”
Get full text

Obesity-driven reprogramming of lung macrophages by Pohan, Clarice

“…Upon further investigation, we found that AMs from high-fat diet fed obese (>30wks) mice had larger lipid droplets than those from young lean (<12wks) and age-matched lean (>30wks) mice. …”
Get full text

PIERCE1: a determinant of left-right asymmetry in mammals by Farley, H

“…<p>The study of mice with heart and situs defects can provide useful models for improving our understanding of congenital heart defects in humans. …”

Local release of rapamycin by microparticles delays islet rejection within the anterior chamber of the eye by Fan, Yanliang, Zheng, Xiaofeng, Berggren, Per-Olof, Loo, Joachim Say Chye, Yusuf Ali

“…Here, we show that islet rejection in the ACE of mice can be significantly suppressed through local delivery of rapamycin by carefully designed sustained-release microparticles. …”
Get full text
Get full text

Build-A-Bae : interrogating female stereotypes in Singapore by Ming Rui, Lee

Get full text

Cortical regulation of sleep by Krone, LB

“…First, I present laminar recordings of neocortical activity during sleep in wild type mice, which suggest that layer 5 actively drives slow waves. …”

Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors by Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole

“…KI mice expressing functional human BCRs promise to accelerate the development of vaccines for HIV and other infectious diseases.…”
Get full text

Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis by Alvarez-Martinez, M, Cox, LS, Pearson, CF, Branchett, WJ, Chakravarty, P, Wu, X, Slawinski, H, Al-Dibouni, A, Samelis, VA, Gabryšová, L, Priestnall, SL, Suárez-Bonnet, A, Mikolajczak, A, Briscoe, J, Powrie, F, O'Garra, A

“…Double-deficient Prdm1^fl/flMaf^fl/flCd4^Cre mice infected with Helicobacter hepaticus developed severe colitis with an increase in T_H1/NK/ILC1 effector genes in LPLs, while Prdm1^fl/flCd4^Cre and Maf^fl/flCd4^Cre mice exhibited moderate pathology and a less-marked type 1 effector response. …”

Cyanographene and graphene acid : the functional group of graphene derivative determines the application in electrochemical sensing and capacitors by Cheong, Yi Heng, Muhammad Zafir Mohamad Nasir, Bakandritsos, Aristides, Pykal, Martin, Jakubec, Petr, Zbořil, Radek, Otyepka, Michal, Pumera, Martin

“…Well‐defined, stoichiometric derivatives of graphene afford many opportunities in fine‐tuning of graphene properties and hence, extend the application potential of this material. …”
Get full text

Design of wideband low-loss reconfigurable reflectarray antenna by Zhang, Xiran

“…It proposes an RRA design that integrates a PIN diode with air gap. The switch of the reconfigurable unit is directly mounted on the reflective element, reducing the loss introduced by the switching device. …”
Get full text

Evaluating new malaria vaccine candidates by Noé, A

“…In a human efficacy study of prime-target vaccination, multi-omic analyses were performed on hepatic fine needle aspirates and peripheral blood samples to study liver TRM and their circulating counterparts. …”

Development of optical transceiver by Sim, Sebastian Shih Wei.

“…For PIN photodiodes, the epitaxial layer was introduced to the structures to act as an intrinsic layer. …”
Get full text

Identification and characterisation of the haematopoietic stem/progenitor cells at risk for leukaemia development following radiation exposure by Verbiest, T

“…Finally, we report on a gender-dependent leukaemic progression and characterisation where 3 Gy irradiated male mice only present with acute myeloid leukemia and irradiated female mice mainly develop leukaemia with a lymphoid phenotype. …”

Environmental enrichment preconditioning prevents chronic social defeat stress-induced memory impairment and hippocampal neurodegeneration by Nik Ramli, Nik Nasihah, Shamsul Adzmi, Nur Adzreen, Nasarudin, Siti Nur Atiqah Zulaikah, Hashim, Mohamad Hisham

“…However, there is a paucity of studies examining the effects of environmental enrichment on learning and memory in chronic social defeat stress (CSDS) models. Male C57BL/6N mice were (n=5) housed in enriched environments for 30 days before undergoing daily social defeat stress by ICR strain aggressor mice over 10 days. …”
Get full text

Optimized core design of a supercritical carbon dioxide-cooled fast reactor by Handwerk, Christopher S. (Christopher Stanley), 1974-

Get full text
Get full text