Spectral domain optical coherence tomography with extended depth-of-focus by aperture synthesis by Bo, En, Liu, Linbo

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Optic disk localization by a robust fusion method by Wong, Tien Yin, Zhang, Jielin, Yin, Fengshou, Liu, Jiang, Baskaran, Mani, Wong, Damon W. K., Cheng, Ching Yu

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Recognition of human activities using a multiclass relevance vector machine by He, Weihua, Yow, Kin Choong, Guo, Yongcai

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OCT Intensity of the Region between Outer Retina Band 2 and Band 3 as a Biomarker for Retinal Degeneration and Therapy by Zeng, Yong, Gao, Shasha, Li, Yichao, Marangoni, Dario, De Silva, Tharindu, Wong, Wai T., Chew, Emily Y., Sun, Xun, Li, Tiansen, Sieving, Paul A., Qian, Haohua

“…Gene replacement therapy in Rs1KO mice reverted the ORB pattern to one resembling WT and increased the Dip ratio. …”
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Microcrystalline Tyrosine (MCT®): a depot adjuvant in licensed allergy immunotherapy offers new opportunities in malaria by Cabral-Miranda, G, Heath, MD, Gomes, AC, Mohsen, MO, Montoya-Diaz, E, Salman, AM, Atcheson, E, Skinner, MA, Kramer, MF, Reyes-Sandoval, A, Bachmann, MF

“…Both MCT and Alum strongly increased immunogenicity of CSP compared to PBS in both C57BL/6 and BALB/c mice. Challenge studies in mice using a chimeric <em>P. bergei</em> expressing CSP of <em>P. vivax</em> demonstrated clinically improved symptoms of malaria with CSP formulated in both MCT and Alum; protection was, however, more pronounced if CSP was formulated in MCT. …”

Meningeal lymphatic function promotes oligodendrocyte survival and brain myelination by das Neves, SP, Delivanoglou, N, Ren, Y, Cucuzza, CS, Makuch, M, Almeida, F, Sanchez, G, Barber, MJ, Rego, S, Schrader, R, Faroqi, AH, Thomas, J-L, McLean, PJ, Oliveira, TG, Irani, SR, Piehl, F, Da Mesquita, S

“…Here, we showed that inducing meningeal lymphatic vessel ablation in adult mice led to gene expression changes in glial cells, followed by reductions in mature oligodendrocyte numbers and specific lipid species in the brain. …”

Chromatin laser imaging reveals abnormal nuclear changes for early cancer detection by Chen, Yu-Cheng, Chen, Qiushu, Tan, Xiaotain, Chen, Grace, Bergin, Ingrid, Muhammad Nadeem Aslam, Fan, Xudong

“…By imaging the lasing emissions from chromatins, we discovered that, despite the absence of observable lesions, polyps, or tumors under stereoscope, high-fat mice exhibited significantly lower lasing thresholds than low-fat mice. …”
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The critical role of IL-23 receptor positive T cells in the pathogenesis of anterior uveitis associated with spondyloarthropathy by Hedley, R

“…</p> <p>Recently, systemic overexpression of IL-23 in mice has shown the accumulation of a small number of γδ T cells proximal to the anterior uvea. …”

Is clicking mechanism good for flapping wing micro aerial vehicle? by Chin, Yao Wei, Lau, Gih Keong

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Endothelial damage arising from high salt hypertension is elucidated by vascular bed systematic profiling by Vinaiphat, Arada, Pazhanchamy, Kalailingam, JebaMercy, Gnanasekaran, Ngan, SoFong Cam, Leow, Melvin Khee-Shing, Ho, Hee Hwa, Gao, Yong-Gui, Lim, Kah-Leong, Richards, A. Mark, de Kleijn, Dominique P. V., Chen, Christopher P., Kalaria, Raj N., Liu, Jian, O'Leary, Deborah D., McCarthy, Neil E., Sze, Siu Kwan

“…Altered protein expression in hypertensive compared to normal mice was characterized by liquid chromatography tandem mass spectrometry. …”
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Experimental and numerical investigations of hot-rolled stainless steel channel section columns susceptible to flexural buckling by Li, Shuai, Zhang, Lulu, Liang, Yating, Zhao, Ou

“…A thorough testing and numerical modelling programme has been conducted to investigate the minor-axis flexural buckling behaviour and resistances of pin-ended hot-rolled stainless steel channel section columns. …”
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Modeling the proactive driving behavior of connected vehicles : a cell-based simulation approach by Zhu, Feng, Ukkusuri, Satish V.

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Functional characterization of orexin system by Chua, Peiling

“…Also, currently there is an absence of a good behavioral paradigm which mimics major depression so we hope to develop one by applying chronic stress through forced swimming test, together with clomipramine, to male wild-type mice. However, the results were not on par with our assumptions as we presumed that the mice will develop depression-like symptoms after 7 days of treatment and we also did not manage to generate the viral vectors. …”
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Focused array analysis of diabetic skin wound. by Ling, Wei Yin.

“…To understand the interplay among these players behind angiogenesis and discover possible therapeutic targets, a focused array approach employing real-time quantitative PCR technique was used to unravel the differential gene molecular profiles in the healing of chronic diabetic mice wounds compared to that of normal wounds. In vivo analyses using wildtype (+/+) and diabetic (ob/ob) mice wounds revealed many angiogenic factors and inflammatory mediators with altered gene expression patterns and levels leading to the chronic inflamed state of diabetic wounds. …”
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In vivo visualization of cells with fluorescent-labeled fab fragment. by Wee, Armanda Lixuan.

“…However, the current use of fluorescent reporter mice and fluorescent-labeled antibodies are accompanied with several limitations that restricts their usefulness for in vivo imaging. …”
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Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome by Alford, KA, Slender, A, Vanes, L, Li, Z, Fisher, EMC, Nizetic, D, Orkin, SH, Roberts, I, Tybulewicz, VLJ

“…We show that although Tc1 mice do not develop leukemia, they have macrocytic anemia and increased extramedullary hematopoiesis. …”

Measuring membrane capacitance during a depolarizing stimulus by Chen, Peng., Gillis, Kevin., Xue, Renhao., Pui, Tze Sian.

“…It is critical to resolve the highly dynamic kinetic steps along the molecular cascade of exocytosis in order to pin down the specific actions of regulatory molecules and eventually decipher this complex and fundamental process.…”
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Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and is Activated by PPARβ/δ Deficiency by Zarei, Mohammad, Barroso, Emma, Leiva, Rosana, Barniol-Xicota, Marta, Pujol, Eugènia, Escolano, Carmen, Vázquez, Santiago, Palomer, Xavier, Pardo, Virginia, González-Rodríguez, Águeda, Valverde, Ángela M., Quesada-López, Tania, Villarroya, Francesc, Wahli, Walter, Vázquez-Carrera, Manuel

“…Increased Fgf21 expression was observed in liver of PPARβ/δ-null mice and in mouse primary hepatocytes when this receptor was knocked down by small interfering RNA (siRNA). …”
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The role of calcium dependent neurotransmission in axon path finding, myelination and maintenance of specified cortical projection neuron populations by Korrell, K

“…</p> <p>Together, the results indicate that neuronal activity has little effect on the onset of myelination but has effects on the g-ratio in deep cortical layer projection neurons in mice.</p>…”

Development of a counter-UAV system by Tang, Wen Yue

“…Upon testing, the firing pin mechanism was found to be unable to reliably puncture the CO2 canister, even after improvements. …”
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