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    The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator by Wong, Brandon Han Siang, Shim, Heesung, Goay, Stephanie Shee Min, Ong, Seow Theng, Nur Ayuni Binte Muhammad Taib, Chai, Kelila Xin Ye, Lim, Kerry, Huang, Dachuan, Ong, Choon Kiat, Vaiyapuri, Thamil Selvan, Cheah, Yeong Cheng, Wang, Yulan, Wulff, Heike, Webster, Richard David, Shelat, Vishalkumar G., Verma, Navin Kumar

    Published 2025
    “…SKA-346 (30 mg kg-1), tolerated by mice after intra-peritoneal administration, exhibited a peak plasma concentration of 6.29 μg mL-1 (29.2 μM) at 15 min and a circulating half-life (t 1/2) of 2.8 h. …”
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    Journal Article
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    Materials cartography: A forward-looking perspective on materials representation and devising better maps by Torrisi, Steven B., Bazant, Martin Z., Cohen, Alexander E., Cho, Min Gee, Hummelshøj, Jens S., Hung, Linda, Kamat, Gaurav, Khajeh, Arash, Kolluru, Adeesh, Lei, Xiangyun, Ling, Handong, Montoya, Joseph H., Mueller, Tim, Palizhati, Aini, Paren, Benjamin A., Phan, Brandon, Pietryga, Jacob, Sandraz, Elodie, Schweigert, Daniel, Shao-Horn, Yang, Trewartha, Amalie, Zhu, Ruijie, Zhuang, Debbie, Sun, Shijing

    Published 2024
    “…We present several promising directions for future research: devising representations of varied experimental conditions and observations, the need to find ways to integrate machine learning into laboratory practices, and making multi-scale informatics toolkits to bridge the gaps between atoms, materials, and devices.…”
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    Article
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