Investigating viral glycosylation pathways for drug and vaccine development by Brun, J

“…Iminosugars, which inhibit N-linked glycan processing enzymes such as endoplasmic reticulum alpha-glucosidase I and II of the glycoprotein quality control pathway, constituted one of the two most promising groups of drugs in this antiviral cellular screen that have not entered clinical trials yet.…”

Topochemical manipulation of some complex transition metal oxides by Amano Patiño, ME

“…This phase is composed of sheets of apex-linked Ni¹⁺O₄ and Ru²⁺O₄ squares in a checkerboard ordered arrangement. …”

Differences in the effectiveness of individual-level smoking cessation interventions by socioeconomic status by Theodoulou, A, Fanshawe, TR, Leavens, E, Theodoulou, E, Wu, AD, Heath, L, Stewart, C, Nollen, N, Ahluwalia, JS, Butler, AR, Hajizadeh, A, Thomas, J, Lindson, N, Hartmann-Boyce, J

“…<p><b>Background</b></p> People from lower socioeconomic groups are more likely to smoke and less likely to succeed in achieving abstinence, making tobacco smoking a leading driver of health inequalities. …”

Early Immune Regulatory Changes in a Primary Controlled Human Plasmodium vivax Infection: CD1c + Myeloid Dendritic Cell Maturation Arrest,... by Yeo, Tsin Wen, Woodberry, Tonia, Loughland, Jessica R., Minigo, Gabriela, Burel, Julie G., Amante, Fiona H., Piera, Kim A., McNeil, Yvette, Good, Michael F., Doolan, Denise L., Engwerda, Christian R., McCarthy, James S., Anstey, Nicholas M.

“…Induction of the kynurenine pathway and increased Treg activation, together with skewed mDC maturation, suggest P. vivax promotes an immunosuppressive environment, likely impairing the development of a protective host immune response.…”
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POWER TO CHOOSE / by Sargent, Haydn, author 656354

Selective lighting up of epiberberine alkaloid fluorescence by fluorophore-switching aptamer and stoichiometric targeting of human telomeric DNA G-quadruplex multimer by Zhang, Lihua, Liu, Hua, Shao, Yong, Lin, Clement, Jia, Huan, Chen, Gang, Yang, Danzhou, Wang, Ying

“…The steady-state absorption, steady-state/time-resolved fluorescence, and NMR studies demonstrate that EPI most likely interact with the 5′ end flanking sequence substructure beyond the core [Q] and the G-quadruplex tetrad in a much more specific manner than the other alkaloids. …”
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Structural analysis of the novel influenza A (H7N9) viral Neuraminidase interactions with current approved neuraminidase inhibitors Oseltamivir, Zanamivir, and Peramivir in the pre... by Tran-To Su, Chinh, Ouyang, Xuchang, Zheng, Jie, Kwoh, Chee Keong

“…Results: Combination of molecular docking and Molecular Dynamics simulation reveal that zanamivir forms more favorable and stable complex than oseltamivir and peramivir when binding to the active site of the H7N9 neuraminidase. And it is likely that the novel influenza A (H7N9) virus adopts a higher probability to acquire resistance to peramivir than the other two inhibitors. …”
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Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology by Gould, E, Fraser, HS, Parker, TH, Nakagawa, S, Griffith, SC, Vesk, PA, Fidler, F, Hamilton, DG, Abbey-Lee, RN, Abbott, JK, Aguirre, LA, Alcaraz, C, Aloni, I, Altschul, D, Arekar, K, Atkins, JW, Atkinson, J, Baker, CM, Barrett, M, Bell, K, Bello, SK, Beltrán, I, Berauer, BJ, Bertram, MG, Wood, A

“…In other words, analyses with results that were far from the mean were no more or less likely to have dissimilar variable sets, use random effects in their models, or receive poor peer reviews than those analyses that found results that were close to the mean. …”

Fiona Patrick - Thesis submitted in partial fulfilment of the degree of Doctor of Clinical Psychology (DClinPsych) by Patrick, F

“…Self-loathing may be a relevant NSB in overweight/obese populations. Considering the likely heterogeneity of overweight/obese populations is important in future work.…”

Forwards in time approaches to understanding genealogies in Λ-Fleming-Viot type models by Wiederhold, B

“…The patterns of isolation by distance reveal that ancestors are more likely to have originated from areas of high population density. …”

Integrated transcriptomic and proteomic profiling of responses to clinical and novel bisphosphonates by Lu, J

“…Pre-clinical studies also indicate that the observed non-skeletal effects of bisphosphonates are likely due to mechanisms beyond inhibition of osteoclasts. …”

Long Covid: a global health issue – a prospective, cohort study set in four continents by Pazukhina, E, Garcia-Gallo, E, Reyes, LF, Kildal, AB, Jassat, W, Dryden, M, Holter, JC, Chatterjee, A, Gomez, K, Søraas, A, Puntoni, M, Latronico, N, Bozza, FA, Edelstein, M, Gonçalves, BP, Kartsonaki, C, Kruglova, O, Gaião, S, Chow, YP, Doshi, Y, Duque Vallejo, SI, Ibáñez-Prada, ED, Fuentes, YV, Hastie, C, O'Hara, ME, Balan, V, Menkir, T, Merson, L, Kelly, S, Citarella, BW, Semple, MG, Scott, JT, Munblit, D, Sigfrid, L

“…Participants in HICs were more likely to report not feeling fully recovered (54.3% vs 18.0%, p<0.001; 56.8% vs 40.1%, p<0.001), fatigue (42.9% vs 27.9%, p<0.001; 41.6% vs 27.9%, p<0.001), new/persistent fever (19.6% vs 2.1%, p<0.001; 20.3% vs 2.0%, p<0.001) and have a higher prevalence of anxiety/depression and impact on usual activities compared with participants in LMICs at 2 to <6 and 6 to <12 months post-COVID-19 hospital discharge, respectively. …”

Consensus on current management of endometriosis by Johnson, NP, Hummelshoj, L, World Endometriosis Society Montpellier Consortium

“…A different group of international experts from those participating in this process would likely have yielded subtly different consensus statements. …”

Internet tool to support self-assessment and self-swabbing of sore throat: development and feasibility study by Lown, M, Smith, KA, Muller, I, Woods, C, Maund, E, Rogers, K, Becque, T, Hayward, G, Moore, M, Little, P, Glogowska, M, Hay, A, Stuart, B, Mantzourani, E, Wilcox, CR, Thompson, N, Francis, NA

“…A web-based tool that helps people assess their sore throat, through the use of clinical prediction rules, taking throat swabs or saliva samples, and taking throat photographs, has the potential to improve self-management and help identify those who are the most and least likely to benefit from antibiotics. <br><strong> Objective:<br></strong> We aimed to develop a web-based tool to help patients and parents or carers self-assess sore throat symptoms and take throat photographs, swabs, and saliva samples for diagnostic testing. …”

Childhood bullying and mental health: understanding risk, resilience, and the role of anti-bullying interventions by Guzman Holst, C

“…Children and young people in these latter groups are more likely to have elevated levels of mental health problems (Singham et al., 2017). …”

Synergy of compress strain and antioxidant of platinum-copper for enhanced the oxygen reduction performance by Zhang, Jun, Liang, Pingjuan, Xu, Xinlan, Wang, Rong, Liu, Shuyue, Wang, Chunyuan, Liu, Boyu, Luo, Laizheng, Jin, Meng, Liu, Huan, Yi, Huan, Lu, Shi-Yu

“…Herein, we report a worm-liked PtCu nanocrystals dispersed on nitrogen-doped carbon hollow microspheres (Pt0.38Cu0.62/N-HCS). …”
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Design, User Experience, and Usability : UX Research and Design : 10th International Conference, DUXU 2021, Held as Part of the 23rd HCI International Conference, HCII 2021, Virtua... by DUXU (Conference) (10th : 2021 : Online), organiser 643242, Soares, Marcelo Marcio, editor 514932, Rosenzweig, Elizabeth, editor 643243, Marcus, Aaron, 1943-, editor 643244, International Conference on Human-Computer Interaction (23rd : 2021 : Online) issuing body 642922

Development of selenization/sulfurization-free CuIn(S,Se)2 for thin film solar cells applications by Wang, Mengxi

“…The vulcanization process occurred between the molecular precursors, when cross-links are formed between metal acetylacetonates and sulfur/selenium powder even before annealing. …”
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Disorder–property relationships in magnetic and pseudospin framework materials by Bulled, J

“…</p> <br> <p>In this thesis, I study the spin and pseudospin disorder in four framework materials—NaMn(HCOO)₃, Tb_{1−<em>x</em>}Y_<em>x</em>(HCOO)₃, [C(NH₂)₃]Mn(_{1−<em>x</em>})Fe_{2<em>x</em>/3}(HCOO)₃, and Cd(CN)₂. I investigate the links between their disordered structures and properties— namely, the magnetocaloric effect, heat capacity, ferrimagnetism, and thermal expansion. …”

Effects of microwave frying on physicochemical properties of edible oils and quality of potato chips by Elfaitouri, Taher A.Houssein

“…Oil was trapped only in intercellular spaces, which was strongly linked to the microstructure (not only in intercellular spaces but also over some cells). …”
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