EN-79AB surface disinfection by UV & effect of repetitive organisms exposure on self disinfecting chemicals by Enkisra, Irfan

“…In contrast, antibiotics can be taken to kill bacteria. Therefore, due to safety constraints, the SARS-CoV2 virus strain was not permitted to be used in this experiment. …”
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Pneumococcal genomics and evolution by van Tonder, A

“…This analysis revealed that the majority of what had previously been described as serotype 6B pneumococci were in fact serotype 6E and serological assays demonstrated that vaccine-induced serotype 6B antibodies were able to kill serotype 6E pneumococci. The analysis of <em>cps</em> loci was then extended to consider the diversity of 49 serotypes and included 5,405 genomes in the analyses. …”

Linking dual mode of action of host defense antimicrobial peptide thanatin: structures, lipopolysaccharide and LptAm binding of designed analogs by Sinha, Sheetal, Dhanabal, Vidhya Bharathi, Sperandeo, Paola, Polissi, Alessandra, Bhattacharjya, Surajit

“…As a mode of bacterial cell killing, thanatin disrupts LPS outer membrane and inhibits LPS transport by binding to the periplasmic protein LptAm. …”
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Injectable cell transplantation system for cytokine-based cancer immunotherapy by Gerard Nathanael Adrianus.

“…Cancer is a major killing disease, causing 6.7 million deaths globally in 2002. …”
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Single-site nanozymes with a highly conjugated coordination structure for antitumor immunotherapy via cuproptosis and cascade-enhanced T lymphocyte activity by Liu, Yang, Niu, Rui, Zhao, Huan, Wang, Yinghui, Song, Shuyan, Zhang, Hongjie, Zhao, Yanli

“…The extracellular matrix (ECM) in the tumor microenvironment (TME) and upregulated immune checkpoints (ICs) on antitumor immune cells impede the infiltration and killing effect of T cells, creating an immunosuppressive TME. …”
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Designer broad-spectrum polyimidazolium antibiotics by Zhong, Wenbin, Shi, Zhenyu, Mahadevegowda, Surendra H., Liu, Bo, Zhang, Kaixi, Koh, Chong Hui, Ruan, Lin, Chen, Yahua, Zeden, Merve S., Pee, Carmen J. E., Marimuthu, Kalisvar, De, Partha Pratim, Ng, Oon Tek, Zhu, Yabin, Chi, Robin Yonggui, Hammond, Paula T., Yang, Liang, Gan, Yunn-Hwen, Pethe, Kevin, Greenberg, E. Peter, Gründling, Angelika, Chan-Park, Mary B.

“…Our experiments indicate PIM1 binds bacterial cell membranes by hydrophobic and electrostatic interactions, enters cells, and ultimately kills bacteria. Unlike cationic AMPs, such as colistin (CST), PIM1 does not permeabilize cell membranes. …”
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Inorganic nanoparticles–driven self–assembly of natural small molecules in water for constructing multifunctional nanocapsules against plant diseases by Liu, Li-Wei, Ding, Zheng-Hao, Ren, Gang-Gang, Wang, Guang-Di, Pan, Xin, Wei, Guo-Hai, Zhou, Xiang, Wu, Zhi-Bing, Jin, Zhi-Chao, Chi, Robin Yonggui, Yang, Song

“…The nanocapsules effectively kill plant–pathogenic bacteria via tight binding to the bacterial surface, inducing reactive oxygen species accumulation and disrupting bacterial cell walls. …”
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Single-molecule diagnostics to support curative interventions for tuberculosis and HIV by Dougan, Tyler J.

“…Tuberculosis is curable, but because of the difficulties of diagnosing it, many people with TB—and the majority of those killed by it—never begin treatment. HIV can be treated with lifelong medication. …”
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Synthesis and application of peptidoglycan oligomers as metabolic labeling agents for bacteria by He, Jingxi

“…Based on all the results presented in this thesis, the synthetic PGOs have been demonstrated applicable to bacterial detection and killing purposes with versatile modifications available in a feasible manner. …”
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The effect of the amyloid-beta peptide on the fluidity of cell membranes : a study by fluorescence correlation spectroscopy by Ng, Justin Wei Qing

“…We thus believe and conclude that within the parameters examined in this study, we have shown that exposing cells to Aβ does not result in changes in membrane fluidity in the short term, even at Aβ concentrations that are sufficient to kill the cells. This information may be of help to researchers planning studies investigating the effects of Aβ on the cell membrane.…”
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Effects of thrombin and its related peptide fragments on neutrophils by Lim, Chun Hwee

“…NET-associated proteins have been argued to trap and kill bacteria, as well as being implicated in autoimmune complications. …”
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Tumor cell-intrinsic signals promoting tolerance and adaptation to oncogenic kinase inhibition by Flower, Cameron Timothy

“…In this thesis, I explore these issues using tractable experimental models in which genotype-matched kinase inhibitors fail to kill or durably arrest proliferation of cancer cells, with particular focus on the role of cellular signaling networks. …”
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New multi-target based therapeutics against an opportunistic superbug by Premkumar, Jayaraman.

“…In the search for more effective strategies to combat the Pseudomonas infections, in vitro activities of antibiotics and natural dietary phytochemicals alone and in combination against P. aeruginosa strains were investigated using the microtitration checkerboard method, fractional inhibitory concentration (FIC) indices and time-kill analysis. Furthermore, to gain a new understanding of the molecular mechanism of synergistic interactions identified from the above study various susceptibility testing methods, confirmatory biochemical assays were performed and also validated using computational evaluation involving molecular docking studies. …”
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Impact of interspecific competition on African wild dogs (Lycaon pictus) in an ecosystem with artificial perennial water provision by Sandoval Serés, ME

“…Secondly, I assessed the level of kleptoparasitism risk for African wild dogs from lions and hyaenas in areas with different waterhole densities and at different distances from waterholes (0 and 5 km away), using playback experiments simulating African wild dog kills and analysing the data with hurdle models (Chapter 3). …”

Malaria parasite stress tolerance is regulated by DNMT2-mediated tRNA cytosine methylation by Hammam, Elie, Sinha, Ameya, Baumgarten, Sebastian, Nardella, Flore, Liang, Jiaqi, Miled, Samia, Bonhomme, Frédéric, Erdmann, Diane, Arcangioli, Benoit, Arimondo, Paola B., Dedon, Peter, Preiser, Peter, Scherf, Artur

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Analysis of lava flow impacts for use in risk assessments by Meredith, Elinor Siwan

“…Some volcanic hazards leave little deposit but can kill everyone in their path, while others move slowly enough to avoid causing fatalities but leave thick solidified deposits that can render land unusable for decades. …”
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A bi-functional three-terminal memristor applicable as an artificial synapse and neuron by Liu, Lingli, Dananjaya, Putu Andhita, Ang, Calvin Ching Ian, Koh, Eng Kang, Lim, Gerard Joseph, Poh, Han Yin, Chee, Mun Yin, Lee, Calvin Xiu Xian, Lew, Wen Siang

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Wage premium in Singapore. by Tan, Ruo Hui., Tan, Yan Yu., Lee, Wai Meng.

“…The following variables that were found to have significant impact: a) Respondents who were themselves, or have family members and close friends being severely injured, sick or killed due to job-related accidents reported higher values, b) respondents who were covered by life and accident insurance reported higher values, c) respondents with higher monthly income before taxes tended to report higher values and d) respondents who received higher education levels reported lower values. …”
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Understanding sudden larch death – from epidemiology to host resistance by Dun, H

“…By 2019 at least 20,700 hectares of larch had been killed due to P. ramorum infection or felled in efforts to contain the pathogen. …”

Effect of detergent, herbs and spices on the growth of Vibrio parahaemolyticus biofilm in seafood by Nillian, Elexson

“…At a minimum of 10 mg/ml (1000 µg/ml), clove was the most effective as it showed MICs at 19.531-78.125 µg/ml and MBC at 78.125-625 µg/ml. The killing time activity with cloves was fast-acting against antibiotic resistant V. parahaemolyticus at 8× MIC in 0.5hr time, while 1 hr, 4 hr, and 8 hr with star anise, lemon leaves, and curry leaves extracts. …”
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