CRISPR-DBA: a deep learning framework for uncertainty quantification of CRISPR off-target activities by Cao, X, Minary, P

Investigating the genetics and immunopathogenesis of ankylosing spondylitis by Liu, F

“…<p>Ankylosing spondylitis is an immune-mediated inflammatory arthritis mainly affecting the spine, although the peripheral joints, skin, intestine, and eyes could also be affected. …”

The role of p53 and ASPP2 in neurodegenerative disease by Turnquist, C

“…Also, LPS induces nuclear ASPP2 <em>in vivo</em> at the blood-cerebral spinal fluid-barrier (BCSFB), the brain's barrier to inflammation. …”

Analog smart I/O pads by Tan, Shyue Mei.

“…ESD is an increasingly significant problem in integrated circuit design as increasing pin counts and faster circuit speeds compound the need for more and better reliable ESD protection. …”
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Tribological properties of wax microcapsule modified polymers by Ang, Ping Lon

“…The tribology test uses the Pin-On-Disk wear test method and the default tribometer settings used in this project were set at 2000m sliding distance, 40cm/s linear speed and 3N linear load. …”
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Effect of emulsion temperature on physical properties of palm oil‐based margarine by Miskandar, M. S., Che Man, Y. B., Yusoff, M. S. A., Abdul Rahman, R.

“…The emulsion temperatures studied were 40, 45, and 50°C, with other parameters such as emulsion flow rates, tube cooler temperature, and pin rotor speed kept constant. The SFC developed during processing and storage at 28°C was measured to evaluate the quality of margarine. …”
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Back to the Basics of SARS-CoV-2 Biochemistry: Microvascular Occlusive Glycan Bindings Govern Its Morbidities and Inform Therapeutic Responses by Scheim, David E., Parry, Peter I., Rabbolini, David J., Aldous, Colleen, Yagisawa, Morimasa, Clancy, Robert, Borody, Thomas J., Hoy, Wendy E.

“…Consistent with the biochemistry of coronaviruses as well established over decades, SARS-CoV-2 makes its initial attachment to host cells through the binding of its spike protein (SP) to sialylated glycans (containing the monosaccharide sialic acid) on the cell surface. …”
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NMDA receptor activation enhances inhibitory GABAergic transmission onto hippocampal pyramidal neurons via presynaptic and postsynaptic mechanisms by Xue, Jiu Gang, Masuoka, Takayoshi, Gong, Xian Di, Chen, Ken-Shiung, Yanagawa, Yuchio, Law, Alex Sai Kit, Konishi, Shiro

“…Thus NMDARs at glutamatergic synapses on both CA1 pyramidal neurons and interneurons appear to exert feedback and feedforward inhibition for determining the spike timing of the hippocampal microcircuit.…”
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Fabrication of heat sinks by Selective Laser Melting for convective heat transfer applications by Wong, Kin Keong, Ho, Jin Yao, Leong, Kai Choong, Wong, Teck Neng

“…Three heat sinks comprising pin fins of circular, rectangular-rounded and aerofoil geometries were fabricated by SLM from aluminium alloy AlSi10Mg powder. …”
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A Novel MIMO antenna integrated with a solar panel and employing AI-equalization for 5G wireless communication networks by Hussein, Humam, Elmunim, Nouf Abd, Atasoy, Ferhat, Virdee, Bal Singh, Elwi, Taha A., Rashid, Nasr, Jayanthi, Renu Karthick Rajaguru, Alibakhshikenari, Mohammad, Limiti, Ernesto

“…We demonstrate that the directivity of this antenna array can be precisely electronically reconfigured using PIN diode switches. Additionally, we show the feasibility of integrating solar panels with the proposed MIMO antenna array. …”
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Feature extraction from EEG signals and regularization for brain-computer interface by Mishuhina, Vasilisa

“…The main motivation behind MI-BCI is to improve life of people with different neuromuscular disorders such as amyotrophic lateral sclerosis, cerebral palsy, stroke, or spinal cord injury, as well as to help them with rehabilitation. …”
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Scaffold-mediated sustained, non-viral delivery of miR-219/miR-338 promotes CNS remyelination by Milbreta, Ulla, Lin, Junquan, Pinese, Coline, Ong, William, Chin, Jiah Shin, Shirahama, Hitomi, Mi, Ruifa, Williams, Anna, Bechler, Marie E., Wang, Jun, ffrench-Constant, Charles, Hoke, Ahmet, Chew, Sing Yian

“…We show that miR-219/miR-338 promoted primary rat OL differentiation and myelination in vitro. Using spinal cord injury as a proof-of-concept, we further demonstrate that miR-219/miR-338 could also be delivered non-virally in vivo using an aligned fiber-hydrogel scaffold to enhance remyelination after a hemi-incision injury at C5 level of Sprague-Dawley rats. …”
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Liquid state machine with dendritically enhanced readout for low-power, neuromorphic VLSI implementations by Roy, Subhrajit, Banerjee, Amitava, Basu, Arindam

“…We show that compared to a single perceptron using analog weights, this architecture for the readout can attain, even by using the same number of binary valued synapses, up to 3.3 times less error for a two-class spike train classification problem and 2.4 times less error for an input rate approximation task. …”
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Characterising the T cell responses to SARS-CoV-2 including variants of concern induced by natural infection and vaccines by Adele, S

“…Chapter 4 expands on T cell responses to VOCs, showing that vaccinated individuals maintain significant T cell reactivity across VOCs despite spike protein mutations that diminish antibody neutralization efficacy. …”

Organic donor-acceptor cocrystals for multiferroic applications by Wang, Zongrui, Zhang, Qichun

“…The cocrystallization strategy has provided an efficient route to fulfill room temperature magnetoelectricity in single phase owing to the long-range ordered π-π stacking (donor-acceptor assembled) network, long-lived excitons (with μs lifetime), spin orders (±1/2 s pin) and charge transfer (CT) dipoles in the assembled crystal lattice. …”
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The Portevin-Le Chatelier effect of Cu-2.0Be alloy during hot compression by Zhu, Daibo, Wu, Na, Liu, Yang, Liu, Xiaojin, Jiang, Chaohua, Jiang, Yanbin, Zhao, Hongyun, Cui, Shuhui, Xie, Guilan

“…As the strain rate increases, the dislocations outpace the diffusion speed of the solute atoms, limiting their ability to effectively pin the dislocations, resulting in lower dislocation density and serration amplitude. …”
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Compatability and equilibrium approach to slender concrete column design (dual project) by Toh, Yi Hui

“…This report evaluates and compares the proposed design method with the Australian code AS3600-2001 for slender concrete column. The failure loads of pin-end columns under short term loading and uniaxial bending are used as a pre-determined factor to analyse the data. …”
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Seroepidemiology of COVID-19 in pregnant women and their infants in Uganda and Malawi across multiple waves 2020-2022 by Hookham, L, Cantrell, L, Cose, S, Freyne, B, Gadama, L, Imede, E, Kawaza, K, Lissauer, S, Musoke, P, Nankabirwa, V, Sekikubo, M, Sommerfelt, H, Voysey, M, PeriCOVID Consortium, Le Doare, K

“…The placental transfer GMR was 1.7, indicating active placental transfer of anti-spike IgG. There was no association between SARS-CoV-2 antibody positivity and adverse pregnancy or infancy outcomes. …”

Wear behaviour of NiTi shape memory alloys by Yan, Lina

“…For example, since mechanical properties of NiTi SMAs are close to those of cortical bones, NiTi SMA based implants such as joint replacements, bone plates, and spine fracture fixations were developed. However, complex wear modes on the surface may cause undesired reactions from neighboring tissues, leading to a serious inflammation of the human body. …”
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Conformable ultrasound breast patch for deep tissue scanning and imaging by Du, Wenya, Zhang, Lin, Suh, Emma, Lin, Dabin, Marcus, Colin, Ozkan, Lara, Ahuja, Avani, Fernandez, Sara, Shuvo, Ikra Iftekhar, Sadat, David, Liu, Weiguo, Li, Fei, Chandrakasan, Anantha P., Ozmen, Tolga, Dagdeviren, Canan

“…The in vitro studies and clinical trials reveal that the array using a piezoelectric crystal [Yb/Bi-Pb(In <jats:sub>1</jats:sub> <jats:sub>/2</jats:sub> Nb <jats:sub>1/2</jats:sub> )O <jats:sub>3</jats:sub> -Pb(Mg <jats:sub>1/</jats:sub> <jats:sub>3</jats:sub> Nb <jats:sub>2/3</jats:sub> )O <jats:sub>3</jats:sub> -PbTiO <jats:sub>3</jats:sub> ] (Yb/Bi-PIN-PMN-PT) exhibits a sufficient contrast resolution (~3 dB) and axial/lateral resolutions of 0.25/1.0 mm at 30 mm depth, allowing the observation of small cysts (~0.3 cm) in the breast. …”
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