Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors by Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole

“…We validate this technology with the rapid generation of three BCR KI lines expressing native human precursors, instead of computationally inferred germline sequences, to HIV broadly neutralizing antibodies. …”
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Aneuploid senescent cells activate NF-κB to promote their immune clearance by NK cells by Wang, Ruoxi W., Viganò, Sonia, Ben-David, Uri, Amon, Angelika, Santaguida, Stefano

“…Inactivating NF‐κB abolishes NK cell‐mediated clearance of untransformed aneuploid cells. In cancer cell lines, NF‐κB upregulation also correlates with the degree of aneuploidy. …”
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How information about historic carbon emissions affects support for climate aid: evidence from a survey experiment by Charnysh, Volha, Kalow, Jared, Lieberman, Evan, Walk, Erin

“…However, in democratic countries such as the United States, it remains uncertain whether such messages can affect public opinion, especially across partisan lines. We conducted a pre-registered survey from a national online pool (N = 5,002) with a built-in experiment to evaluate the effectiveness of alternative communications strategies associated with historic carbon emissions in increasing support for climate aid. …”
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A novel low-crosstalk driveline based on spoof surface plasmon polaritons by Zhao, Shumin, Zhang, Hao Chi, Liu, Liangliang, Zhao, Jiahao, Yang, Cheng

“…By using traditional drivelines, for example, microstrip lines, the distance between adjacent drivelines should be large enough to reduce the multichannel coupling effects. …”
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Fullwave modeling of coplanar-waveguide discontinuities for applications in filter design and metamaterial characterization by Gao, Jing

“…Coplanar waveguide (CPW) has been finding wide applications in microwave integrated circuit (MIC) and monolithic microwave integrated circuit (MMIC) due to several advantages it offers over microstrip lines. Typical discontinuities characteristics are an integral part of practical circuit design. …”
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New techniques for automated architectural reconstruction from photographs by Werner, T, Zisserman, A

“…Second, we develop and refine a technique for piecewise planar model fitting involving sweeping polygonal primitives, and assess the performance of this technique. Third, lines at infinity are constructed from image correspondences and used to sweep planes in the principal directions. …”

Integrative taxonomy clarifies the evolution of a cryptic primate clade by van Elst, T, Sgarlata, GM, Schüßler, D, Tiley, GP, Poelstra, JW, Scheumann, M, Blanco, MB, Aleixo-Pais, IG, Rina Evasoa, M, Ganzhorn, JU, Goodman, SM, Hasiniaina, AF, Hending, D, Hohenlohe, PA, Ibouroi, MT, Iribar, A, Jan, F, Kappeler, PM, Le Pors, B, Manzi, S, Olivieri, G, Rakotonanahary, AN, Rakotondranary, SJ, Rakotondravony, R

“…Here we illustrate best practices for clarifying cryptic diversification processes by presenting an integrative framework that leverages multiple lines of evidence and taxon-informed cut-offs for species delimitation, while placing special emphasis on identifying patterns of isolation by distance. …”

Antitumor polycyclic acridines. 7. Synthesis and biological properties of DNA affinic tetra- and pentacyclic acridines by Stanslas, Johnson, Hagan, Damien J., Ellis, Michael J., Turner, Claire, Carmichael, James, Ward, Wynne, Hammonds, Timothy R., Stevens, Malcolm F. G.

“…The novel water-soluble agent dihydroindolizino[7,6,5-kl]acridinium chloride 14 has inhibitory activity in a panel of non-small-cell lung and breast tumor cell lines exceeding that of m-AMSA. The salt inhibited the release of minicircle products of kDNA confirming that disorganization of topoisomerase II partly underlies the activity of the compound. …”

Development of nanocomposite dielectric materials for high energy density capacitor applications by Lin, Meng-Fang

“…The core-shell structured ceramic-polymer nanocomposite was developed using two different types of cross-linking agents via in-situ synthesis method without any catalyst and initiators. …”
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Synthetic approaches to all-porphyrin nanorings by Field, J

“…However, construction of directly-linked porphyrin-porphyrin bonds under the standard oxidative coupling conditions used to construct the linear oligomers appears to be incompatible with this template-directed approach. …”

Cellular reporter for inflammation. by Yuhanis Abdullah Sunny.

“…Currently, there are commercial green fluorescent protein (GFP) assays available for in vitro cell lines only. There are no in vivo systems that can report NF-B activation in hematopoietic stem cells. …”
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Laser surface treatment of 50CrMo4 steel by Chew, Han Xin

“…The speed of laser is significance in affecting the width and depth of the laser treated lines. When the speed is too high, the change is not visible, thus, the hardness test cannot be done on the cross section area.…”
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Design Experiences as Pathways for Embracing Failure by Das, Madhurima, Yang, Maria C

“…This study establishes a set of failure-related interventions implemented in an introductory design course, and then examines potential links to students’ experiences and attitudes towards failure. …”
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Contradictions and compromises in sustainability planning: The case of the sub-Arctic city of Yakutsk, Russia by Durova, Aleksandra, Ryan, Brent D.

“…The study underscores that these tensions are intricately linked to historical, political, planning, and governance contexts and reflect the complexities of urban development politics. …”
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Approach temperament and self-esteem : moderators in the relationship between capitalisation and outcomes by S Ashwin Pillai

“…To address this gap, we explored the moderating role of dispositions in the links between work-family interpersonal capitalisation and two intrapersonal outcomes. …”
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Mitigating quantization effects on distributed sensor fusion : a least squares approach by Zhu, Shanying, Chen, Cailian, Xu, Jinming, Guan, Xinping, Xie, Lihua, Johansson, Karl Henrick

“…In this paper, we consider the problem of sensor fusion over networks with asymmetric links, where the common goal is linear parameter estimation. …”
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Mechanical properties of the superficial biofilm layer determine the architecture of biofilms by Kundukad, Binu, Seviour, Thomas, Liang, Yang, Rice, Scott A., Kjelleberg, Staffan, Doyle, Patrick S.

“…Further, the physical properties of the polysaccharides are closely linked to the specific architectures formed by the developing biofilm.…”
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Conceptualize, design, simulate and develop a contact tracing scheme based on the Android platform by Woon, Tse Liang

“…These beacons have a certain identifier linked to it such that when an app that is already installed on the user device picks it up, it will be able to obtain the data. …”
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Construction of hole-transported MoO₃₋ₓ coupled with CdS nanospheres for boosting photocatalytic performance via oxygen-defects-mediated Z-scheme charge transfer by Wu, Yan, Wang, Hou, Tu, Wenguang, Wu, Shuyang, Chew, Jia Wei

“…It is indicated that the PVP not only served as the reducing agent for the formation of oxygen defects in MoO₃₋ₓ, but also the cross-linking agent for the coupling between MoO₃₋ₓ and CdS. …”
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Take a “selfie” : examining how leaders emerge from leader self-awareness, self-leadership, and self-efficacy by Bracht, Eva M., Keng-Highberger, Fong T., Avolio, Bruce J., Huang, Yiming

“…In the present work, we contribute toward closing this gap by testing a mediation chain linking a leader's leader self-awareness to a follower's leadership emergence with two time-lagged studies (nstudy1 = 449, nstudy2 = 355). …”
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