Quantitative proteomics reveals CLR interactome in primary human cells by Manolis, D, Hasan, S, Maraveyas, A, O'Brien, DP, Kessler, BM, Kramer, H, Nikitenko, LL

“…The G protein-coupled receptor (GPCR) calcitonin receptor-like receptor (CLR) mediates essential functions in several cell types and is implicated in cardiovascular pathologies, skin diseases, migraine and cancer. To date, the network of proteins interacting with CLR ("CLR interactome") in primary cells, where this GPCR is expressed at endogenous (physiologically relevant) levels, remains unknown. …”

Post-deployment adaptation with access to source data via federated learning and source-target remote gradient alignment by Wagner, F, Li, Z, Saha, P, Kamnitsas, K

“…We demonstrate the method’s effectiveness using multi-center databases for the tasks of cancer metastases detection and skin lesion classification, where our method compares favourably to previous work. …”

Coordination chemistry and biological activity of bidentate and quadridentate nitrogen–sulfur donor ligands and their complexes by H. Tarafder, M. Tofazzal, Ali, A. Manaf, Elias, M. Suhaimi, Crouse, Karen A., Silong, Sidik

“…The SnII complex and the SNNS free Schiff base were very effective against Melanoma (skin cancer cells). The SBDTC and its SnII complex were also very effective against Renal carcinoma (kidney cancer cells). …”

Evaluation of anti-tyrosinase, anti-collagenase, and in vitro sun protection factor (SPF) of Ajwa date fruit (Phoenix dactylifera L.) by Ramli, Nur Asyiqin, Gani, Siti Salwa Abd, Halmi, Mohd Izuan Effendi, Zaidan, Uswatun Hasanah

“…Therefore, research has demonstrated this study’s promise in skin pigmentation, elasticity, and UV protection. …”
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Experimental and numerical studies of S960 ultra-high strength steel welded I-section columns by Su, Andi, Liang, Yating, Zhao, Ou

“…A testing programme, including initial geometric imperfection measurements and ten pin-ended column tests, was conducted. The testing programme was accompanied by a numerical modelling programme, where finite element models were firstly developed and validated against the test results, and then employed to perform parametric studies to generate further numerical data. …”
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Structure-activity relationships of photo-activated soft tissue Adhesive by Wicaksono, Gautama

“…Soft tissue fixation relies on mechanical means such as sutures, pins, and screws, with potential complications such as concentrated tissue damage, perforation, and the need for secondary surgeries. …”
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Modeling of electric MHD flow of nanoparticles in a CMC-water based casson hybrid nanofluid over a porous medium by Alkasasbeh, Hamzeh Taha, Hanandeh, Feras A., Aljunaeidia, Bajes Z., Al-Olaimat, Nesreen M., Alzyout, Abduallah M., Khalil, Sara A., Muhammad Khairul Anuar, Mohamed

“…The impact of these parameters on velocity and temperature profiles, as well as on the skin friction coefficient and Nusselt number of the nanofluid, is observed. …”
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Dual layer composite nanofiltration hollow fiber membranes for low-pressure water softening by Setiawan, Laurentia, Shi, Lei, Wang, Rong

“…Therefore, the development of novel NF membranes with a positively charged skin has become a key issue for low pressure water softening. …”
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Cytotoxic and genotoxic characterization of titanium dioxide, gadolinium oxide, and poly(lactic-co-glycolic acid) nanoparticles in human fibroblasts by Das, Gautom Kumar, Loo, Joachim Say Chye, Leong, David Tai, Ng, Kee Woei, Xiong, Sijing, Zhao, Xinxin, Setyawati, Magdiel Inggrid, Khoo, Pheng Kian Stella, Eng, Bao Hui, Tan, Timothy Thatt Yang

“…To evaluate nanoparticle-induced genotoxicity more realistically, a human skin fibroblast cell line (BJ) with less mutated genotype compared with cancer cell line was used. …”
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Self-assembly of solubilized human hair keratins by Lai, Hui Ying, Setyawati, Magdiel Inggrid, Abdul Rahim Ferhan, Divakarla, Shiva Kamini, Chua, Huei Min, Cho, Nam-Joon, Chrzanowski, Wojciech, Ng, Kee Woei

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Hydrophobic bioadhesive composites for human motion detection by Singh, Manisha, Solic, Ivan, Steele, Terry W. J.

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Modeling of outdoor natural ventilation and energy performance for buildings in an industrial park by Tan, Joel Heang Kuan.

“…The hotter air would then be more buoyant than the surrounding air thus gaining velocity and rise upwards. By having a double skin roof, the top roof would be heated causing air between both roofs to flow thereby causing convection. …”
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Murine cd4+ T cell Responses are inhibited by cytotoxic T cell-mediated killing of dendritic cells and are restored by antigen transfer by Ma, Joel Zhi-Iong, Lim, So Nai, Qin, Jim Shixiang, Yang, Jianping, Enomoto, Noriyuki, Ruedl, Christiane, Ronchese, Franca

“…Residual CD4+ T cell proliferation was due to the transfer of antigen from carrier DC to host APC, and predominantly involved skin DC populations. Importantly, the proliferating CD4+ T cells also developed into IFN-γ producing memory cells, a property normally requiring direct presentation by activated DC. …”
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Novel single-step hydrophobic modification of polymeric hollow fiber membranes containing imide groups : its potential for membrane contactor application by Zhang, Yuan, Wang, Rong, Zhang, Lizhi, Fane, Anthony Gordon

“…Experiments reveal that the modification changed the membrane morphology and structure, resulted in surface pore opening and thinning down of the membrane skin layer. As a compromise between the membrane hydrophobicity and mechanical strength, 10–30 min were considered as appropriate modification times for the PAI membranes. …”
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Perceptions of a Buruli ulcer controlled human infection model: How, who, and why? by Muhi, S, Schmidt, S, Marshall, JL, O’Brien, DP, Johnson, PDR, McCarthy, JS, Jamrozik, E, Osowicki, J, Stinear, TP

“…Background: Infection with Mycobacterium ulcerans causes slowly progressive skin lesions known as Buruli ulcer (BU). An M. ulcerans controlled human infection model (MuCHIM) is likely to accelerate our understanding of this otherwise neglected disease, and may be an efficient platform for testing vaccines and other interventions. …”

Hybrid nanofluid radiative flow across a permeable convective moving surface with heat generation: numerical and statistical approach by Wahid, Nur Syahirah, Mustafa, Mohd Shafie, Md Arifin, Norihan, Khashi’ie, Najiyah Safwa, Pop, Ioan

“…Optimal conditions for the skin friction coefficient and flow bifurcation delay are identified which demonstrates effective control over fluid dynamics. …”

Al2O3-Cu hybrid nanofluid flow and heat transfer characteristics in the duct with various triangular rib configurations by Togun, Hussein, Homod, Raad Z., Sultan Aljibori, Hakim S., Abed, Azher M., Alias, Hajar, Hussein, Ahmed Kadhim, Biswal, Uddhaba, Al-Thamir, Mohaimen, Mahdi, Jasim M., Mohammed, Hayder I., Ahmadi, Goodarz

“…Key findings include: (1) the 60° rib configuration produced the highest local heat transfer coefficient, with the maximum occurring at the rib centers. (2) Increasing nanofluid concentration and Reynolds number enhanced heat transfer but reduced skin friction. (3) The optimal performance was achieved with 2 vol.% Al2O3–Cu at Re = 60,000. (4) Velocity contours revealed larger recirculation zones for 60° ribs compared to 45° and 90° configurations. (5) Turbulent kinetic energy was highest for 60° ribs, contributing to enhanced thermal performance. …”

女性媒介形象建构与话语权赋权 ——《脱口秀大会》系列为例 = Female discourse power and construction of female image —— Rock&Roast stand-up comedy series... by 郭跃男, Guo, Yuenan

“…Traditional forms Chinese comedy, represented by comic strips (xiao pin) and sketches (xiang sheng), has been produced by and for the gaze of male, both in terms of its historical development and the content. …”
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High-speed and high-photocurrent InP-based uni-traveling-carrier photodiode by Meng, Qianqian

“…Compared to conventional PIN-PD, UTC-PD has a unique mode of operation where only faster electrons serve as the active carriers, which can reduce the space charge effect and lead to much higher current, and higher speed operations. …”
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Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted Combretum Indicum leaves by Thanaseelan, Tanesha, D. Nurul, Hidayu, Nurul, Sahirah, Rajaletchumy, Veloo Kutty

“…Combretum Indicum (CI), which contains numerous bioactive compounds, has been used in traditional medicine for a variety of reasons, including the treatment of skin conditions. This study investigates the antioxidant and anti-tyrosinase activities of CI leaves extracted using different surfactants (Triton X-100 and Vitamin E TPGS) at concentrations of 1%, 2%, and 3%, as well as various alcohol solvents (acetone, methanol, and ethanol) at concentrations of 50%, 70%, and 90%. …”
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