Assessing the origin of and potential for international spread of Chikungunya virus from the Caribbean by Khan, Kamran, Bogoch, Isaac, Brownstein, John S., Miniota, Jennifer, Nicolucci, Adrian, Hu, Wei, Nsoesie, Elaine O., Cetron, Martin, Creatore, Maria Isabella, German, Matthew, Wilder-Smith, Annelies

“…Conclusion: The rapidly evolving outbreak of chikungunya in the Caribbean poses a growing risk to countries and areas linked by air travel, including the United States where competent Aedes mosquitoes exist. …”
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Integrated transcriptomics, metabolomics, and lipidomics profiling in rat lung, blood, and serum for assessment of laser printer-emitted nanoparticle inhalation exposure-induced di... by Guo, Nancy Lan, Poh, Tuang Yeow, Pirela, Sandra, Farcas, Mariana T., Chotirmall, Sanjay Haresh, Tham, Wai Kin, Adav, Sunil S., Ye, Qing, Wei, Yongyue, Shen, Sipeng, Christiani, David C., Ng, Kee Woei, Thomas, Treye, Qian, Yong, Demokritou, Philip

“…Furthermore, the systematic analysis revealed PEPs-induced transcriptomic changes linking to other disease risks in rats, including diabetes, congenital defects, auto-recessive disorders, physical deformation, and carcinogenesis. …”
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Oncofetal HMGA2 attenuates genotoxic damage induced by topoisomerase II target compounds through the regulation of local DNA topology by Ahmed, Syed Moiz, Dröge, Peter

“…Here, we demonstrate that HMGA2 significantly enhanced the DNA supercoil relaxation activity of the drug target TOP2A and that this activator function is mechanistically linked to HMGA2’s known ability to constrain DNA supercoils within highly compacted ternary complexes. …”
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Three essays on national and organizational cultures by Kawasaki, Shota

“…Chapter 2 illustrates a novel pathway linking employees’ perceptions of organizational cultural strength to job satisfaction and organizational commitment via organizational nostalgia (i.e., one’s sentimental longing or wistful affection for past organizational events). …”
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PrimeNet: a framework for commonsense knowledge representation and reasoning based on conceptual primitives by Liu, Qian, Han, Sooji, Cambria, Erik, Li, Yang, Kwok, Kenneth

“…People have the ability to efficiently organize vast amounts of knowledge by linking or generalizing concepts using a limited set of conceptual primitives that serve as the fundamental building blocks of reasoning. …”
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Hepatic effects of prolonged oral administration of Aqueous extracts from Trigonella foenum-graecum (Fenugreek) seeds explored through pathology techniques by Okorie, Nnaemeka, Ibe, Onyekachi Ewa, Okekpa, Simon Imakwu, Nwakpa, Anthony Chukwudi, Agom, Dansy Daniel, Pauline, Iyke-Ogbo, Adaeze, Obi Laura, Mmesomachi, Uche Bethel, Nyirahafashimana, Valentine, Obi, Ihuoma A.

“…Introduction: The escalating global prevalence of complementary and alternative medicine is often linked to the financial challenges of conventional healthcare in developing nations. …”
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Fabrication of bilayer nanofibrous-hydrogel scaffold from bacterial cellulose, PVA, and gelatin as advanced dressing for wound healing and soft tissue engineering by Khan, Rawaiz, Aslam Khan, Muhammad Umar, Stojanović, Goran M., Javed, Aneela, Haider, Sajjad, Abd. Razak, Saiful Izwan

“…FTIR confirmed cross-linking of both the top and bottom layers, and SEM showed porous structure for the bottom layer, random deposition of NFs on the surface, and aligned NFs in the cross section. …”
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Combining laser frequency combs and iodine cell calibration techniques for Doppler detection of exoplanets by Cahoy, K., Fischer, D., Spronck, J., Demille, D.

“…We propose a fiber-fed high precision spectrograph design that combines the existing ~5000-6000 A Iodine calibration system with a high-precision Laser Frequency Comb (LFC) system from ~6000-7000 A that just meets the redward side of the Iodine lines. The scientific motivation for such a system includes: a 1000 A span in the red is currently achievable with LFC systems, combining the two calibration methods increases the wavelength range by a factor of two, and moving redward decreases the 'noise' from starspots. …”
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Sequence-Dependent & -Independent Effects of Intron-Mediated Enhancement (IME) by Kowal, Emma J. K.

“…In this study we report the design and execution of several massively parallel reporter assays (MPRAs), interrogating the effect of tens of thousands of synthetic and natural intron sequences on gene expression in the human HEK293T and HeLa cell lines. We observe that even with random internal sequence, most of these introns splice well and trigger IME. …”
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Multi-criteria re-entrant jobs scheduling problems using GA and AHP by Lin, Danping.

“…The validation is conducted in two experiments, firstly single GA is implemented for the re-entrant lines and later a new combination of GA and AHP is carried out. …”
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Study of cascade failures of power grids by Ng, Jason Wei Long.

“…The substations and the transmission lines are denoted as the nodes and edges of the complex network respectively. …”
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EMS of hybrid AC/DC micro grid by Zhao, Yi

“…The issues coming along with traditional power system can be terrible for the environments, such as large use of fossil fuels, coal; long distance of transmission lines also will cause the cost of money and fuels for the electricity transmission process. …”
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The role of CD1a in dengue infection by Yang, J

“…To investigate the effect of dengue infection on the function of CD1a-reactive T cells, polyclonal blood T cells from patients and controls, and CD1a-autoreactive T cells clone/lines were utilised. The production of IFN-γ and GM-CSF by CD1a-autoreactive T cells was reduced when co-cultured with dengue-infected presenting cells. …”

Development of coherent detector technologies for sub-millimetre wave astronomy observations by Tan, B-K

“…</p> <p>Using the current 16-pixel 350 GHz SIS receiver, HARP-B, we have observed the ¹²CO J=3→2 emission lines from two nearby galaxies. An important result we found is that the ¹²CO J=3→2 correlates strongly with the 8 μm Polycyclic Aromatic Hydrocarbon emission.…”

Structure and inhibition of novel cyclin-dependent kinases by Dixon-Clarke, S

“…Preliminary trials using these relatively non-selective compounds to inhibit CDK16 in melanoma and medulloblastoma cancer cell lines revealed rebastinib as the more efficacious drug causing loss of cell proliferation in the 1-2 micromolar range. …”

Dwelling encounters: migration, diversity and ambivalence in an Istanbul neighborhood by Biehl, K

“…In this dissertation I apply a novel theoretical approach drawing on the concept of dwelling for understanding how residents of Kumkapı relate to their environment and make sense of it. I propose three lines of argument that unfold sequentially through the organizing structure of the thesis. …”

An aerodynamic investigation of a high-pressure turbine using rotor casing static pressure measurements at engine representative conditions with different tip designs, tip gaps, an... by Singh, D, Beard, PF, Cardwell, D, Staelens, V, Bahulekar, P, Stokes, M, Bather, S, Chana, K

“…Steady and unsteady casing static pressure measurements were acquired, using pneumatic lines and high-frequency response (∼100 kHz) Kulite pressure transducers, respectively. …”

Key transcriptional regulators of neutrophil function in inflammation by Ai, Z

“…</p> <p>To investigate the regulatory role of the selected TFs in neutrophils, I utilised HoxB8 myeloid progenitors as a model system for in vitro production of neutrophils and generated stable knockout lines for JUNB, RELB, IRF5, RFX2, KLF6, and RUNX1 in Hoxb8 myeloid progenitors, using the CRISPR/Cas9 mediated system. …”

BRCA1 regulation of breast cancer cell motility by Hernandez Nuñez, ZE

“…Time-lapse microscopy of breast cancer cell lines with various BRCA1 backgrounds was employed to evaluate the impact of inhibiting ubiquitin ligase activity. …”

How are cognitive maps formed and encoded in humans? by Glitz, L

“…In Chapter 4, we find evidence for the latter, with trajectory training resulting in neural encoding of the map that is more similar to separate transitive lines along rows and columns, the extent of which is related to behavioural accuracy. …”