Quantitative proteomics reveals CLR interactome in primary human cells by Manolis, D, Hasan, S, Maraveyas, A, O'Brien, DP, Kessler, BM, Kramer, H, Nikitenko, LL

“…The G protein-coupled receptor (GPCR) calcitonin receptor-like receptor (CLR) mediates essential functions in several cell types and is implicated in cardiovascular pathologies, skin diseases, migraine and cancer. To date, the network of proteins interacting with CLR ("CLR interactome") in primary cells, where this GPCR is expressed at endogenous (physiologically relevant) levels, remains unknown. …”

Post-deployment adaptation with access to source data via federated learning and source-target remote gradient alignment by Wagner, F, Li, Z, Saha, P, Kamnitsas, K

“…We demonstrate the method’s effectiveness using multi-center databases for the tasks of cancer metastases detection and skin lesion classification, where our method compares favourably to previous work. …”

End-to-end simulation of high-contrast imaging systems: methods and results for the PICTURE mission family by Douglas, Ewan S., Hewawasam, Kuravi, Mendillo, Christopher B., Cahoy, Kerri L, Cook, Timothy A., Finn, Susanna C. Finn, Howe, Glenn A., Kuchner, Marc, J., Lewis, Nikole K., Marinan, Anne D., Mawet, Dimitri, Chakrabarti, Supriya

“…Simulated science observations of the predicted warm ring around Epsilon Eridani illustrate the performance of both missions.…”
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Comparative analysis of changes in retinal layer thickness following femtosecond laser-assisted cataract surgery and conventional cataract surgery by Surl, Dongheon, Kim, Seungmin, Kim, Sangyeop, Kim, Tae-Im, Seo, Kyoung Yul, Jun, Ikhyun

“…The average retinal thickness of the four inner macular ring quadrants was used for comparative analysis. …”
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Transient prediction of nanoparticle-laden droplet drying patterns through dynamic mode decomposition by Tanis-Kanbur, Melike Begum, Kumtepeli, Volkan, Kanbur, Baris Burak, Ren, Junheng, Duan, Fei

“…The developed data-driven approach has also achieved the acceptable prediction for the droplet diameter with less than 0.13% error and a coffee-ring thickness over a range of 2.0 to 6.7 μm. Moreover, the proposed machine learning algorithm can recognize the volume of the droplet liquid and the transition of the drying regime from one to another according to the predicted contact line and the droplet height.…”
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Characterization of the biosynthetic gene cluster and shunt products yields insights into the biosynthesis of balmoralmycin by Ma, Guang-Lei, Xin, Lingyi, Liao, Yanghui, Chong, Zhi-Soon, Candra, Hartono, Pang, Li Mei, Lee, Sean Qiu En, Gakuubi, Martin Muthee, Ng, Siew Bee, Liang, Zhao-Xun

“…Four of the coproducts (compounds 528) are novel compounds that feature a highly oxygenated or fragmented lactone ring, and three of them (compounds 325) exhibited cytotoxicity against the human pancreatic cancer cell line MIA PaCa-2 with IC50 values ranging from 0.9 to 1.2 mg/mL. …”
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Temperature and burning history affect emissions of greenhouse gases and aerosol particles from tropical peatland fire by Kuwata, Mikinori, Kai, Fuu Ming, Yang, Liudongqing, Itoh, Masayuki, Gunawan, Haris, Harvey, Charles F.

“…Mass spectrometric analysis of organic components indicated that aerosol particles emitted at higher temperatures had more unsaturated bonds and ring structures than that emitted from cooler fires. …”
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Mechanical and microstructural characteristics of high-strength self-compacting concrete (HSSCC) with optimal silica fume and fly ash cement replacement by Aliyu Azare, Ahmed, Mohd Haziman, Wan Ibrahim, Faisal Alshalif, Alshalif, Putra Jaya, Ramadhansyah, Nindyawati, Nindyawati

“…These aspects entailed fresh properties’ verification, slump flow, T500, J-ring, segregation resistance, and compressive strength on newly incorporated properties. …”
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Nanothermite composites with a novel cast curable fluoropolymer by Nie, Hongqi, Tan, Li Ping, Pisharath, Sreekumar, Hng, Huey Hoon

“…Herein, we report the synthesis of a novel cast curable fluoropolymer (FP) with 58 wt% fluorine content produced through the cationic ring opening polymerization of 3-Perfluorohexyl-1, 2-epoxypropane. …”
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Sessile droplet evaporation on patterned surfaces by Ng, Aaron Chin Liang

“…With a bigger particle size, the coffee-ring pattern becomes less dominant which slowly transitions into a uniform pattern. …”
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Gold-catalyzed intramolecular animation of alcohol pro-electrophiles as novel synthetic strategies to nitrogen heterocycles by Prasath Kothandaraman

“…In Chapter V, gold-catalyzed tandem ring opening/amination of secondary and tertiary 2-tosylaminophenylcyclopropyl carbinols is introduced as an efficient synthetic route to 2,3-dihydro-1H-benzo[b]azepines as well as 2-vinylindolines. …”
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Study of cascade failures of power grids by Ng, Jason Wei Long.

“…Complex networks have been the recent model that researchers adopted so as to study the power grid in greater detail. Making use of the ring network topology, the power grid is then modeled into a complex network. …”
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PDMS-coated porous PVDF hollow fiber membranes for efficient recovery of dissolved biomethane from anaerobic effluents by Sethunga, Godakooru Sethunga Mudiyanselage Dilhara Prebhashwari, Karahan, Huseyin Enis, Wang, Rong, Bae, Tae-Hyun

“…The adjustment of the concentration of PDMS precursor mix could effectively serve for tuning the performance characteristics of MC membranes and helped suppress membrane wetting, a major performance-reducing factor. Despite their denser skin layers, the lumen-modified membranes demonstrated superior dCH4 recovery flux. …”
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3D printing of mycelium engineered living materials using a waste-based ink and non-sterile conditions. by Soh, Eugene, Teoh, Jia Heng, Leong, Brendon, Xing, Tingrong, Le Ferrand, Hortense

“…Mycelium is the vegetative parts of the fungi which forms an interconnected network, covering air-material interfaces with a dense skin. An agar gel was chosen as the printing medium and supplemented with coffee grounds, malt and peptone to double the growth rate and density of the mycelium by Pleurotus ostreatus. …”
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Hybrid nanofluid radiative flow across a permeable convective moving surface with heat generation: numerical and statistical approach by Wahid, Nur Syahirah, Mustafa, Mohd Shafie, Md Arifin, Norihan, Khashi’ie, Najiyah Safwa, Pop, Ioan

“…Optimal conditions for the skin friction coefficient and flow bifurcation delay are identified which demonstrates effective control over fluid dynamics. …”

Al2O3-Cu hybrid nanofluid flow and heat transfer characteristics in the duct with various triangular rib configurations by Togun, Hussein, Homod, Raad Z., Sultan Aljibori, Hakim S., Abed, Azher M., Alias, Hajar, Hussein, Ahmed Kadhim, Biswal, Uddhaba, Al-Thamir, Mohaimen, Mahdi, Jasim M., Mohammed, Hayder I., Ahmadi, Goodarz

“…Key findings include: (1) the 60° rib configuration produced the highest local heat transfer coefficient, with the maximum occurring at the rib centers. (2) Increasing nanofluid concentration and Reynolds number enhanced heat transfer but reduced skin friction. (3) The optimal performance was achieved with 2 vol.% Al2O3–Cu at Re = 60,000. (4) Velocity contours revealed larger recirculation zones for 60° ribs compared to 45° and 90° configurations. (5) Turbulent kinetic energy was highest for 60° ribs, contributing to enhanced thermal performance. …”

Self-assembly of solubilized human hair keratins by Lai, Hui Ying, Setyawati, Magdiel Inggrid, Abdul Rahim Ferhan, Divakarla, Shiva Kamini, Chua, Huei Min, Cho, Nam-Joon, Chrzanowski, Wojciech, Ng, Kee Woei

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Hydrophobic bioadhesive composites for human motion detection by Singh, Manisha, Solic, Ivan, Steele, Terry W. J.

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Modeling of outdoor natural ventilation and energy performance for buildings in an industrial park by Tan, Joel Heang Kuan.

“…The hotter air would then be more buoyant than the surrounding air thus gaining velocity and rise upwards. By having a double skin roof, the top roof would be heated causing air between both roofs to flow thereby causing convection. …”
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Murine cd4+ T cell Responses are inhibited by cytotoxic T cell-mediated killing of dendritic cells and are restored by antigen transfer by Ma, Joel Zhi-Iong, Lim, So Nai, Qin, Jim Shixiang, Yang, Jianping, Enomoto, Noriyuki, Ruedl, Christiane, Ronchese, Franca

“…Residual CD4+ T cell proliferation was due to the transfer of antigen from carrier DC to host APC, and predominantly involved skin DC populations. Importantly, the proliferating CD4+ T cells also developed into IFN-γ producing memory cells, a property normally requiring direct presentation by activated DC. …”
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