DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11 by Loh Jia Tong, Teo, Joey Kay Hui, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Andiappan, Anand Kumar, Lim, Hong-Hwa, Lam, Kong-Peng

“…Knocking out Dok3 enhanced the production of the cytokine IFN-γ by T cells, which conferred protection against experimental atopic dermatitis-like skin inflammation in mice. The expression of DOK3 was increased in T cells isolated from patients with atopic dermatitis and inversely correlated with IFNG expression. …”
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Engineering nano-nodular pattern on the substrate surface by tuning phase inversion to construct ultrapermselective ion-separation nanofiltration membrane by Zhao, Yali, Li, Can, Liao, Yuan, Yin, Yurong, Wang, Rong, Chen, Dongliang

“…Consequently, a PA membrane with nano-nodular pattern, thin skin layer, narrow pore size distribution and negative charge was formed. …”
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Computation fluid dynamics on drag reduction II by Zang, Bin

“…Lastly, the grid size and RANS models are subjected to further verification to ensure the observations and calculations are indeed trustworthy and relatively accurate by studying skin friction coefficient and comparing to empirical formula; also by simulating more complex dimpled flow with different Reynolds number regimes. …”
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A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data by Murrin, O, Mounier, N, Voller, B, Tata, L, Gallego-Moll, C, Roso-Llorach, A, Carrasco-Ribelles, LA, Fox, C, Allan, LM, Woodward, RM, Liang, X, Valderas, JM, Khalid, S, Dudbridge, F, Lamb, SE, Mancini, M, Farmer, L, Boddy, K, Bowden, J, Melzer, D, Frayling, TM, Masoli, JAH, Pilling, LC, Violán, C, Delgado, J

“…Many across-domain pairs exhibited substantial shared genetics (e.g., iron deficiency anaemia and peripheral arterial disease: genetic correlation 𝑅𝑔 = 0.45 [95% Confidence Intervals 0.27:0.64]). 33 pairs displayed negative genetic correlations, such as skin cancer and rheumatoid arthritis (𝑅𝑔 = −0.14 [−0.21:−0.06]), due to potential adverse drug effects. …”

Association between feel-like temperatures and injury risk during international outdoor athletic championships: a prospective cohort study on 29 579 athlete starts during 10 champi... by Edouard, P, Dandrieux, P-E, Klöwer, MK, Junge, A, Racinais, S, Branco, P, Hollander, K, Navarro, L

“…We performed Poisson regressions with incidence rates (number of injuries per 1000 athlete starts) as outcomes and UTCI as a predictive variable adjusted for sex, for all and time-loss injuries, for different injured tissue types (ie, muscle, tendon, ligament, articular, bone and skin) and specific discipline (ie, sprints, hurdles, jumps, throws, middle distance, long distance, marathon and race walking).…”

Fractional exhaled nitric oxide (FeNO) among school children in Java and Sumatra, Indonesia: associations with respiratory symptoms, house dust mite sensitization and the home envi... by Norbäck, Dan, Hashim, Jamal Hisham, Hashim, Zailina, Jalaludin, Juliana, Ismail, Rohaida, Wieslander, Gunilla, Wispriyono, Bambang, Sary, Lolita, Pratama, Satria, Sari, Meliana, Sisinta, Tiaraima, Putra, Hondli, Perdana, Agung Aji, Muhani, Nova, Lestari, Sri Maria Puji, Wulandari, Ririn, Nurmala, Eliza Eka

“…Methods: Data on health and home were collected by a face-to face interview before measuring FeNO and performing skin prick test against common allergens. Exploratory linear mixed and logistic regression models were employed. …”
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Infectious diseases acquired by international travellers visiting the USA by Stoney, Rhett J, Esposito, Douglas H., Kozarsky, Phyllis, Hamer, Davidson H., Grobusch, Martin P., Gkrania-Klotsas, Effrossyni, Libman, Michael, Gautret, Philippe, Lim, Poh Lian, Leder, Karin, Schwartz, Eli, Sotir, Mark J., Licitra, Carmelo

“…Travellers presented with a range of illnesses; skin and soft tissue infections of unspecified aetiology were the most frequently reported during travel (29 diagnoses, 14% of during-travel diagnoses); arthropod bite/sting was the most frequently reported after travel (173 diagnoses, 15% after-travel diagnoses). …”
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Viral proteases activate the CARD8 inflammasome in the human cardiovascular system by Nadkarni, Rhea, Chu, Wern Cui, Lee, Cheryl Q. E., Mohamud, Yasir, Yap, Lynn, Toh, Gee Ann, Beh, Sheryl, Lim, Radiance, Fan, Michelle Yiyun, Zhang, Lyanne Yizhuo, Robinson, Kim, Tryggvason, Karl, Luo, Honglin, Zhong, Franklin, Ho, Lena

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Three physiological responses in fathers and non-fathers’ to vocalizations of typically developing infants and infants with Autism Spectrum Disorder by Esposito, Gianluca, Valenzi, Stefano, Islam, Tanvir, Bornstein, Marc H.

“…Three convergent methodologies (Galvanic Skin Response—GSR; cardiac dynamics via Inter-Beat Interval—IBI; right hand temperature change—RHTC) were performed on two groups with contrasting caregiving experience: fathers of typically developing children (n = 10) and non-fathers (n = 10). …”
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Investigating the genetics and immunopathogenesis of ankylosing spondylitis by Liu, F

“…<p>Ankylosing spondylitis is an immune-mediated inflammatory arthritis mainly affecting the spine, although the peripheral joints, skin, intestine, and eyes could also be affected. …”

Enantiomeric glycosylated cationic block co-beta-peptides eradicate Staphylococcus aureus biofilms and antibiotic-tolerant persisters by Zhang, Kaixi, Du, Yu, Si, Zhangyong, Liu, Yang, Turvey, Michelle E., Raju, Cheerlavancha, Keogh, Damien, Ruan, Lin, Jothy, Subramanion Lachumy, Reghu, Sheethal, Marimuthu, Kalisvar, De, Partha Pratim, Ng, Oon Tek, Mediavilla, José R., Kreiswirth, Barry N., Chi, Robin Yonggui, Ren, Jinghua, Tam, Kam C., Liu, Xue-Wei, Duan, Hongwei, Zhu, Yabin, Mu, Yuguang, Hammond, Paula T., Bazan, Guillermo C., Pethe, Kevin, Chan-Park, Mary Bee Eng

“…Its antibacterial activity is superior to that of vancomycin in MRSA mouse and human ex vivo skin infection models, with no acute in vivo toxicity in repeated dosing in mice at above therapeutic levels. …”
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Sensitivity study of weather research and forecasting physical schemes and evaluation of cool coating effects in Singapore by weather research and forecasting coupled with urban ca... by Zhou, Mandi, Long, Yongping, Zhang, Xiaoqin, Donthu, Eswara V. S. K. K., Ng, Bing Feng, Wan, Man Pun

“…Maximum T2 reduction of 3.1°C and surface skin temperature (TSK) reduction of 9.8°C due to cool coating is found at 13:00 at certain locations. …”
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Rationalisation of antifungal properties of α-helical pore-forming peptide, mastoparan B by Lim, Edward Jianyang, Goh, Eunice Tze Leng, Tram, Nhan Dai Thien, Periayah, Mercy Halleluyah, Ee, Rachel Pui Lai, Barkham, Timothy Mark Sebastian, Poh, Zhi Sheng, Verma, Navin Kumar, Lakshminarayanan, Rajamani

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Carbene-based bioadhesive blended with amine, thiol, and acrylate liquid additives by Ellis, Elizabeth, Djordjevic, Ivan, Muhammad Naziruddin Bin Mohd Ali, Steele, Terry W. J.

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Conformal human-machine integration using highly bending-insensitive, unpixelated, and waterproof epidermal electronics toward metaverse by Wei, Chao, Lin, Wansheng, Wang, Liang, Cao, Zhicheng, Huang, Zijian, Liao, Qingliang, Guo, Ziquan, Su, Yuhan, Zheng, Yuanjin, Liao, Xinqin, Chen, Zhong

“…Regardless of whether being flat or bent, the BUW epidermal interface can be conformally attached to the human skin for real-time, comfortable, and unrestrained interactions. …”
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Low magnetic field exposure alters prostate cancer cell properties by Lange, Sigrun, Inal, Jameel, Kraev, Igor, Dart, Dafydd Alwyn, Uysal-Onganer, Pinar

“…These included cancerous, metabolic, blood, skin, cardiac and skeletal Disease Pathways, as well as pain and developmental disorders. …”
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Formulation, optimization and characterization of palm kernel oil esters nanoemulsion system containing sodium diclofenac by Rezaee, Malahat

“…Permeation study was carried out by using cellulose acetate membrane and Wistar male rat skin. Opt.F and F-2 had the higher percentage of drug release. …”
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Synthesis and optical study of lead halide perovskites for opto-electronic applications by Ha, Son Tung

“…These methods usually result in polycrystalline film with many pin-holes and defects. As a physicist, my first aim is to find a way to prepare highest quality, single crystal samples for studying their intrinsic and fundamental properties. …”
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Exploring and Exploiting Ribonuclease 1: from Protein Biochemistry to Protein Engineering by Wralstad, Evans Christian

“…This raises the question: how are these secretory enzymes able to preserve catalytic competency in oxidatively challenging extracellular environments such as blood serum and even epidermal skin? In Chapter 2 of this thesis, the intrinsic antioxidative capacity of RNase 1 is described. …”
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Engineering Mechanical Counter Pressure Spacesuits and Compression Garments: Active Pressurization and Design for Mobility by Kothakonda, Akshay

“…The process of estimating the optimum fabric pattern will be iterative and the resulting pattern may comprise of a composite of different fabric types with varying parameters. Mapping skin Lines of Non-Extension (LoNE’s) informs contours for inextensible cables in such a way that they do not impede movements. …”
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