Clinical course, immunogenicity, and efficacy of BNT162b2 mRNA vaccination against SARS-CoV-2 infection in liver transplant recipients by Tan, Eunice X., Lim, Wen Hui, Thong, Elizabeth, Chavatte, Jean-Marc, Zhang, Jinyan, Lim, Jonathan, Jin, Jocelyn Y., Lim, Daniel R. X., Kang, Jaclyn Y. T., Tang, Ansel Shao Pin, Chan, Kai En, Tan, Caitlyn, Tan, Shi Ni, Nah, Benjamin, Huang, Daniel Q., Wang, Lin-Fa, Tambyah, Paul A., Somani, Jyoti, Young, Barnaby Edward, Muthiah, Mark D.

“…We measured the antibody response against the SARS-CoV-2 spike protein using the Roche Elecsys immunoassay to the receptor-binding domain of the SARS-CoV-2 spike protein, and the presence of neutralizing antibodies was measured by the surrogate virus neutralization test (cPass) before first and second doses of vaccination and also between 2 and 3 mo after the second dose of vaccination. …”
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Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in K... by Lugano, D, Kutima, B, Kimani, M, Sigilai, A, Gitonga, J, Karani, A, Akech, D, Karia, B, Ziraba, AK, Maina, A, Lambisia, A, Omuoyo, D, Mugo, D, Lucinde, R, Owuor, S, Konyino, G, Newman, J, Bailey, D, Nduati, E, Githinji, G, Agoti, CN, Bejon, P, Scott, JAG, Agweyu, A, Warimwe, GM

“…The majority of these mutations mainly target the spike protein, allowing the new variants to escape the immunity previously raised by vaccination and/or infection by earlier variants of SARS-CoV-2. …”

An immunoinformatic approach for identifying and designing conserved multi-epitope vaccines for coronaviruses by Ong, Yu Chuan, Tejo, Bimo Ario, Yap, Wei Boon

“…Methods: This study utilized an immunoinformatic approach to identify evolutionarily conserved CD4+ (HTL) and CD8+ (CTL) T cells, and B-cell epitopes in the coronaviral spike (S) glycoprotein. Results: A total of 132 epitopes were identified, with the majority of them found to be conserved across the bat CoVs, pangolin CoVs, endemic coronaviruses, SARS-CoV-2, and Middle East respiratory syndrome coronavirus (MERS-CoV). …”
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What does sounding Singaporean mean? by Tan, Charmaine Li Min

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Unraveling the Dynamics of Mental and Visuospatial Workload in Virtual Reality Environments by Bernal, Guillermo, Jung, Hahrin, Yassı, İsmail Emir, Hidalgo, Nelson, Alemu, Yodahe, Barnes-Diana, Tyler, Maes, Pattie

“…Our findings indicate a broadband increase in EEG power just prior to a helper event, followed by a spike of visuospatial engagement (parietal alpha and beta 0-1-3 s) occurring concurrently with a decrease in mental workload (frontal theta 2–4 s), and subsequent decreases in visuospatial engagement (parietal theta at 14 s) and physiological arousal (HRV at 20 s). …”
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Analysis and reduction of mismatch in silicon neurons by Shuo, Sun, Basu, Arindam

“…The method presented allows the corrected neurons to compute both rate codes and spike time codes in a mismatch resilient fashion…”
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A high efficiency buck converter for IoT sensors by Mo, Mingwei

“…When the system is activated for data collection and processing, the load current may spike to tens of milliamperes. Thus, it's essential for the DC-DC converter to accommodate a broad spectrum of load currents, ensuring versatility and reliability in various operational states. …”
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Synaptic devices towards neuromorphic electronics by Datta, Indira

“…Area Transfer curves, gate voltage hysteresis loops, and multilevel resistance modulation were studied, and biological functions including long-term potentiation and Depression (LTP and LTD), Excitatory and Inhibitory Postsynaptic Current (EPSC and IPSC), Spike Amplitude and Duration Dependent Plasticity (SADP and SDDP), Paired Pulse Facilitation and Depression (PPF and PPD), and repeated learning and forgetting curves were emulated by our novel device. …”
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Modeling of functional materials : perovskite solar cells by Aruj Shukla

“…However, for a more holistic analysis of perovskite light harvesters as replacement to the existing TiO2 nano particles, a more nuanced modeling and analysis which incorporates a study of transport properties such as trapping effects (for further spike in efficiency), photo catalytic reaction kinetics and surface & bulk defects (for easier fabrication) is demanded as an integral part of future research plans.…”
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The impacts of US Fed interest rate liftoff on Southwest Asia stock markets, sovereign bond and currencies by Ooi, Teik Khim

“…Based on the more reliable model I (using FFF), it implies the negative effect of spike in VIX dominated the positive effect from lower market expectation on interest rate lift-off, which led to decline in ASEAN financial market during 2015 A SEAN slump.…”
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High wavenumber coherent structures in low re apg-boundary-layer transition flow—a numerical study by Lo, Edmond Yat-Man, Chen, Weijia

“…Both parts are imbedded at the primary Λ-vortex stage and spatially coincide with the spike region and high shear layer. The tip part is associated with the later first ring-like vortex, while the rear part with the remainder of the Λ-vortex. …”
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Time to fill up India’s strategic oil reserves by Narula, K

“…Although oil stocks are generally not released to manage oil prices (the IEA’s intention is to stabilize the market and release stocks only in case of physical shortages), it may be possible to use the stored oil to offset a spike in oil prices, especially for developing countries which have administered oil prices.…”

Modelling Malaysia air quality data using Bayesian Structural Time Series models by Aeshah Mohammed, Mohd Aftar Abu Bakar, Mahayaudin M. Mansor, Noratiqah Mohd Ariff

“…The BSTS model integrates three main techniques: The structural model, which employs the Kalman filter approach to model trend and seasonality components; spike and slab regression for variable selection; and Bayesian model averaging to estimate the best-performing prediction model while accounting for uncertainty. …”
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Demand for higher education in Singapore. by Chia, Wilson., Yap, Si Guan., Teo, Bee Cheng.

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Managing employee turnover by Ayse Irem Aydogdu, Tan, Betty, Wong, Fook Seng

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Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds by Wamhoff, Eike-Christian, Ronsard, Larance, Feldman, Jared, Knappe, Grant A., Hauser, Blake M., Romanov, Anna, Case, James Brett, Sanapala, Shilpa, Lam, Evan C., Denis, Kerri J. St., Boucau, Julie, Barczak, Amy K., Balazs, Alejandro B., Diamond, Michael S., Schmidt, Aaron G., Lingwood, Daniel, Bathe, Mark

“…Here, we investigate thymus-independent DNA origami as an alternative material for multivalent antigen display using the receptor binding domain (RBD) of the SARS-CoV-2 spike protein, the primary target of neutralizing antibody responses. …”
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Rapid and Scalable Production of Functional SARS-CoV-2 Virus-like Particles (VLPs) by a Stable HEK293 Cell Pool by Puarattana-aroonkorn, Sitthiphol, Tharakaraman, Kannan, Suriyawipada, Disapan, Ruchirawat, Mathuros, Fuangthong, Mayuree, Sasisekharan, Ram, Artpradit, Charlermchai

“…We employed the membrane, envelope, and highly immunogenic spike proteins of SARS-CoV-2 to produce virus-like particles (VLPs) using the HEK293-F cell line as a host system with an economical transfection reagent. …”
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Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells by Carlevaro-Fita, Joana, Rahim, Anisa, Guigó, Roderic, Johnson, Rory, Vardy, Leah Karen Anne

“…Here we make a global, absolute estimate of the cytoplasmic and ribosome-associated population of stringently filtered lncRNAs in a human cell line using polysome profiling coupled to spike-in normalized microarray analysis. Fifty-four percent of expressed lncRNAs are detected in the cytoplasm. …”
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《史记·滑稽列传》四题 = Four topics on memoir of Guji in Shiji by 曲景毅 Qu, Jingyi

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Does minority dissent encourage creativity? by Leong, Heng Wah., Li, Eugene Ming., Tan, Chu Chien.

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