Roles of leucine-rich alpha-2-glycoprotein 1 in normal and diabetic wound healing by Liu, Chenghao

“…Western blot analysis shows reduced formation of neutrophil extracellular traps in the wounds of diabetic Lrg1-/- mice. Neutrophils isolated from Lrg1-/- mice are less susceptible to inducer of ΝΕΤs formation. …”
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A two-dimensional co-rotational Timoshenko beam element with XFEM formulation by Xu, Jin, Lee, Chi King, Tan, Kang Hai

“…Pin connections and plastic hinges produce non-smooth displacement fields in beam structures. …”
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Evaluating new malaria vaccine candidates by Noé, A

“…Single cell analyses identified several subpopulations, mutual clonality, and indicated a potential developmental trajectory shared between TRM and TRM-like cells. This thesis demonstrates the potential for using TRM-like cells as a correlate of prime-target induced protection against liver-stage malaria. …”

Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria by Panda, Saswati, Zhang, Jing, Tan, Nguan Soon, Ho, Bow, Ding, Jeak Ling

“…AID−/− mice lacking IgG were susceptible to infection, unless reconstituted with natural IgG. …”
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Evaluation of the Digital Ventilated Cage® system for circadian phenotyping by Tir, S, Foster, RG, Peirson, SN

“…Home cage activity in C57BL/6J mice was recorded under a range of lighting conditions, along with circadian clock-deficient cryptochrome-deficient mice (Cry1−/−, Cry2−/− double knockout). …”

Study of heat transfer through micro-structured surfaces by Chin, Wei Hao

“…Each chip has a different microstructure in the form of very small and elongated pin-fins, which will in turn affect the critical heat flux of each component. …”
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Discovery of COVID-19 protein inhibitors in phenolic acids of azadirachta indica (neem) using docking and pharmacokinetics by Roney, Miah, Huq, AKM Moyeenul, Mohd Fadhlizil Fasihi, Mohd Aluwi

“…The most attractive antiviral targets of SARS-CoV-2 are the spike protein and main protease (Mpro). In this work, sixteen phenolic acids of Azadirachta indica were docked into the active site of the spike protein and Mpro. …”
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B cell receptor repertoire kinetics after SARS-CoV-2 infection and vaccination by Kotagiri, P, Mescia, F, Rae, WM, Bergamaschi, L, Tuong, ZK, Turner, L, Hunter, K, Gerber, PP, Hosmillo, M, Hess, C, Clatworthy, MR, Goodfellow, IG, Matheson, NJ, McKinney, EF, Wills, MR, Gupta, RK, Bradley, JR, Bashford-Rogers, RJM, Lyons, PA, Smith, KGC

“…Infection generates a broad distribution of SARS-CoV-2-specific clones predicted to target the spike protein, while a more focused response after vaccination mainly targets the spike's receptor-binding domain. …”

Studies on fiber reinforced thermoplastic composite and their characteristics by Nagarajan Sathish

“…When gauge length of Elvax 3185 matrix specimen was increased from IOmm to 138mm, the maximum load reduced and tensile strength increased, but for the HDPE matrix specimen the phenomena were exactly opposite. Like single yam, the laminate’s characteristics also differed for different fiber volume ratio. …”
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Metronidazole causes skeletal muscle atrophy and modulates muscle chronometabolism by Manickam, Ravikumar, Oh, Hui Yun Penny, Tan, Chek Kun, Paramalingam, Eeswari, Wahli, Walter

“…Furthermore, metronidazole in SPF mice decreases hind limb muscle weight and results in smaller fibers in the tibialis anterior muscle. …”
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Mitofusins Mfn1 and Mfn2 are required to preserve glucose- but not incretin-stimulated β-cell connectivity and insulin secretion by Georgiadou, Eleni, Muralidharan, Charanya, Martinez, Michelle, Chabosseau, Pauline, Akalestou, Elina, Tomas, Alejandra, Yong, Fiona Su Wern, Stylianides, Theodoros, Wretlind, Asger, Legido-Quigley, Cristina, Jones, Ben, Lopez-Noriega, Livia, Xu, Yanwen, Gu, Guoqiang, Alsabeeh, Nour, Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Ali, Yusuf, Soleimanpour, Scott A., Linnemann, Amelia K., Rodriguez, Tristan A., Rutter, Guy A.

“…In contrast, oral glucose tolerance was more modestly affected in βMfn1/2-dKO mice, and glucagon-like peptide 1 or glucose-dependent insulinotropic peptide receptor agonists largely corrected defective glucose-stimulated insulin secretion through enhanced EPAC-dependent signaling. …”
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Synaptic devices towards neuromorphic electronics by Datta, Indira

“…This report examines potentially brain-like structures and their cognitive behaviour including learning, forgetting, and relearning, as well as synaptic behaviour such as short and long-term plasticity. …”
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High wavenumber coherent structures in low re apg-boundary-layer transition flow—a numerical study by Lo, Edmond Yat-Man, Chen, Weijia

“…Both parts are imbedded at the primary Λ-vortex stage and spatially coincide with the spike region and high shear layer. The tip part is associated with the later first ring-like vortex, while the rear part with the remainder of the Λ-vortex. …”
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Obesity-driven reprogramming of lung macrophages by Pohan, Clarice

“…Upon further investigation, we found that AMs from high-fat diet fed obese (>30wks) mice had larger lipid droplets than those from young lean (<12wks) and age-matched lean (>30wks) mice. …”
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PIERCE1: a determinant of left-right asymmetry in mammals by Farley, H

“…<p>The study of mice with heart and situs defects can provide useful models for improving our understanding of congenital heart defects in humans. …”

Cortical regulation of sleep by Krone, LB

“…First, I present laminar recordings of neocortical activity during sleep in wild type mice, which suggest that layer 5 actively drives slow waves. …”

Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors by Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole

“…KI mice expressing functional human BCRs promise to accelerate the development of vaccines for HIV and other infectious diseases.…”
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Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis by Alvarez-Martinez, M, Cox, LS, Pearson, CF, Branchett, WJ, Chakravarty, P, Wu, X, Slawinski, H, Al-Dibouni, A, Samelis, VA, Gabryšová, L, Priestnall, SL, Suárez-Bonnet, A, Mikolajczak, A, Briscoe, J, Powrie, F, O'Garra, A

“…Double-deficient Prdm1^fl/flMaf^fl/flCd4^Cre mice infected with Helicobacter hepaticus developed severe colitis with an increase in T_H1/NK/ILC1 effector genes in LPLs, while Prdm1^fl/flCd4^Cre and Maf^fl/flCd4^Cre mice exhibited moderate pathology and a less-marked type 1 effector response. …”

A paper-based glucose sensoring microneedle patch by Zheng, Shu

“…By diagnose this index can detect many diseases like diabetes. However, the current most methods of clinical analysis of the glucose level need to pierce skin to take blood sample or takes a long time to analyze which will cause skin infection and uncomfortable of patients. …”
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The development of automatic flexible endoscopes for gastrointestinal inspection or surgery by Phee, Louis Soo Jay.

“…Colonoscopy is commonly used in the diagnosis of colonic pathology like cancer of the colon. At present, the colonoscopic procedure is often unpleasant for the patient and technically demanding for the endoscopist. …”
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