Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation by Jackman, Joshua Alexander, Linardy, Eric, Yoo, Daehan, Seo, Jeongeun, Ng, Wei Beng, Klemme, Daniel J., Wittenberg, Nathan J., Oh, Sang-Hyun, Cho, Nam-Joon

“…A plasmonic nanohole sensor for virus-like particle capture and virucidal drug evaluation is reported. …”
Get full text
Get full text

DRD-UNet, a UNet-like architecture for multi-class breast cancer semantic segmentation by Ortega-Ruíz, Mauricio Alberto, Karabağ, Cefa, Roman-Rangel, Edgar, Reyes-Aldasoro, Constantino Carlos

“…This paper describes a UNet-like deep learning architecture called DRD-UNet, which adds a novel processing block called DRD (Dilation, Residual, and Dense block) to a UNet architecture. …”
Get full text

Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines by Sherry, L, Bahar, MW, Porta, C, Fox, H, Grehan, K, Nasta, V, Duyvesteyn, HME, De Colibus, L, Marsian, J, Murdoch, I, Ponndorf, D, Kim, S, Shah, S, Carlyle, S, Swanson, JJ, Matthews, S, Nicol, C, Lomonossoff, GP, Macadam, AJ, Fry, EE, Stuart, DI, Stonehouse, NJ, Rowlands, DJ

“…Continued use of these vaccines, however, threatens ultimate disease eradication and achievement of a polio-free world. Virus-like particles (VLPs) that lack a viral genome represent a safer potential vaccine, although they require particle stabilization. …”

Bacteriocin-like peptides encoded by a horizontally acquired island mediate Neisseria gonorrhoeae autolysis by Poncin, K, McKeand, SA, Lavender, H, Kurzyp, K, Harrison, OB, Roberti, A, Melia, C, Johnson, E, Maiden, MCJ, Greaves, DR, Exley, R, Tang, CM

“…The nap island in the gonococcus encodes 3 cationic, bacteriocin-like peptides which have no detectable antimicrobial activity. …”

Distinct movement disorders in contactin-associated-protein-like-2 antibody-associated autoimmune encephalitis by Gövert, F, Abrante, L, Becktepe, J, Balint, B, Ganos, C, Hofstadt-van Oy, U, Krogias, C, Varley, J, Irani, SR, Paneva, S, Titulaer, MJ, de Vries, JM, Boon, AJW, Schreurs, MWJ, Joubert, B, Honnorat, J, Vogrig, A, Ariño, H, Sabater, L, Dalmau, J, Scotton, S, Jacob, S, Melzer, N, Bien, CG, Geis, C, Lewerenz, J, Prüss, H, Wandinger, K-P, Deuschl, G, Leypoldt, F

“…In the elderly, anti-LGI1 and contactin associated protein like 2 (CASPR2) antibody-associated diseases compose a relevant fraction of autoimmune encephalitis. …”

The cellular characterization of SARS-CoV-2 spike protein in virus-infected cells using the receptor binding domain binding specific human monoclonal antibodies by Chan, Conrad En-Zuo, Ng, Ching-Ging, Lim, Angeline Pei-Chew, Seah, Shirley Lay-Kheng, Chye, De-Hoe, Wong, Steven Ka-Khuen, Lim, Jie-Hui, Lim, Vanessa Zi-Yun, Lai, Soak-Kuan, Wong, Pui-San, Leong, Kok-Mun, Liu, Yi-Chun, Sugrue, Richard J., Tan, Boon Huan

“…While all five antibodies bound conformational-specific epitopes within SARS-CoV-2 spike (S) protein, only PD5, PD7, and SC23 were able to bind to the receptor binding domain (RBD). …”
Get full text

Line inductance stability operation domain assessment for weak grids with multiple constant power loads by Wang, Rui, Sun, Qiuye, Ma, Dazhong, Qin, Dehao, Gui, Yonghao, Wang, Peng

“…Based on this, the conventional impedance-based stability operation point assessment approaches should be expanded into stability domain assessment approach considering the line inductance variation. Therefore, the stability-oriented line inductance stability domain assessment approach for weak grids with CPLs is proposed in this paper. …”
Get full text

Evaluating the ecotoxicity of agropesticides and environmental water contaminants using cell-line and zebrafish embryonic assays by Tan, Roy Zi Hao

“…The objective of the study was to assess the toxicity of common commercial agropesticides using both cell-line and zebrafish embryonic assays as model organisms, as well as briefly evaluate environmental waters in agriculture-dominated sites using Chiang Mai, Northern Thailand as a case study. …”
Get full text

Study of line-commutated Thyristor inverter under voltage dips and novel ride-through solution by Tian, Hongying.

“…An analysis of commutation failure of three-phase line commutated thyristor inverters in the event of a single phase dip. …”
Get full text

On-line ... from Asia to the world - Asian women's NGOs make use of new communication technologies by Cabrera-Balleza, Marvic

Get full text
Get full text

Tunable surface-plasmon-polariton filter constructed by corrugated metallic line and high permittivity material by Luo, Jiang, He, Jin, Apriyana, Alit, Feng, Guangyin, Huang, Qijun, Zhang, Yue Ping

“…The tuning is done by embedding a high permittivity BST dielectric block into the gap of SPP transmission line (T-line). An obvious transmission dip at the certain frequency is observed due to Fabry-Pérot interference. …”
Get full text
Get full text

Dynamic imaging of micro-particles in 3D using lensless in-line digital holographic microscopy by Singh, Vijay Raj, Darakis, Emmanouil, Anand, Asundi

“…In this paper, dynamic imaging of micro-particles in 3D using lensless in-line digital holographic microscopy (LIDHM) is explored. …”
Get full text
Get full text

Experimental verification of breeding performance of fast reactor blankets. by Wu, Shin-Shyong.

Get full text

Antigen presentation dynamics shape the antibody response to variants like SARS-CoV-2 Omicron after multiple vaccinations with the original strain by Yang, Leerang, Van Beek, Matthew, Wang, Zijun, Muecksch, Frauke, Canis, Marie, Hatziioannou, Theodora, Bieniasz, Paul D, Nussenzweig, Michel C, Chakraborty, Arup K

“…After the first dose, limited antigen availability in germinal centers (GCs) results in a response dominated by B cells that target immunodominant epitopes that are mutated in an Omicron-like variant. After the second dose, these memory cells expand and differentiate into plasma cells that secrete antibodies that are thus ineffective for such variants. …”
Get full text

Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration by James, Rachel E., Schalks, Renee, Browne, Eleanor, Eleftheriadou, Ioanna, Munoz, Carmen Picon, Mazarakis, Nicholas D., Reynolds, Richard

“…Here we tested the hypothesis that persistent production of these cytokines in the meningeal compartment and diffusion into underlying GM can drive chronic MS-like GM pathology. Lentiviral transfer vectors were injected into the sagittal sulcus of DA rats to deliver continuous expression of TNF + IFNγ transgenes in the meninges and the resulting neuropathology analysed after 1 and 2 months. …”
Get full text

Perisytiharan oleh Duli Yang Maha Mulia Canselor Universiti Teknologi Malaysia berkenan melantik Yang Berbahagia Tan Sri Dato' Seri (Dr.)... by Universiti Teknologi Malaysia 495834, Abdullah Ayub, Tan Sri Dato' 1926-, addressee 457791, Sultanah Zanariah Almarhum Tunku Ahmad, signer 655367

Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation by Schneikert, Jean, Chandra, Shree Harsha Vijaya, Ruppert, Jan Gustav, Ray, Suparna, Wenzel, Eva Maria, Behrens, Jürgen

“…We show here that colon cancer cell lines express also the paralog APC-like (APCL or APC2). …”
Get full text
Get full text

Phytochemical analysis and cytotoxic effects of mango (Mangifera indica L) kernel on breast cancer cell lines by Abdullah, Al-Shwyeh Hussah

“…Although numerous study has been done on plants to discover new drugs for the treatment of chronic diseases like cancer, the products of the mango plant species Mangifera indica L. waterlily, particularly the kernel have not adequately investigated. …”
Get full text

Enriching the methanol generation via CO2 photoconversion over the cockscomb-like fibrous silica copper by Mahadi, Bahari, Che Rozid, Mamat, Aishah, Abdul Jalil, Shing, Lo Sook, Nurul Sahida, Hassan, F. F.A., Aziz, Alhassan, Mansur, Mohd Ghazali, Mohd Nawawi, Kamarizan, Kidam, Herma Dina, Setiabudi

Get full text
Get full text

Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptors by Luo, Dahai

“…The RIG-I-like receptors (RLRs)—RIG-I, MDA5, and LGP2—detect intracellular pathogenic RNA and elicit an antiviral immune response during viral infection. …”
Get full text
Get full text