Treatment options to support the elimination of Hepatitis C: an open label, factorial randomised controlled trial by Cooke, G, Le Manh, H, Flower, B, McCabe, L, Vu Thu Kim, H, Vo Thi, T, Dang Trong, T, Nguyen Thanh, D, Le Thanh, P, Dao Bach, K, Nguyen Thi Chau, A, Pham Ngoc, T, Vu Thu Thu, H, Dang Thi, B, Nguyen Kim, T, Ansari, A, Le Ngoc, C, Vo Minh, Q, Nguyen Thi Ngoc, P, Le Thi, T, Nguyen Bao, T, Kestelyn, E, Kingsley, C, Van Doorn, R, Rahman, M, Pett, S, Thwaites, G, Barnes, E, Day, J, Nguyen Van Vinh, C, Walker, AS

“…No randomised trials have compared these regimens and high cure rates may be achievable with shorter durations of therapy.…”

Characterization of artemisinin resistance in plasmodium falciparum by Rocamora, Frances Maureen C.

“…In order to better understand the Artemisinin resistance phenotype, we developed Artemisinin-resistant parasite lines derived from two isogenic clones (6A and 11C) of the 3D7 strain of Plasmodium falciparum using a selection regimen that mimics how parasites interact with the drug in infected patients. …”
Get full text

Characterisation of novel electroactive consortia from environmental samples enriched through potentiostatic growth by Doyle, Lucinda Elizabeth

“…Comparison revealed the enriched community from canal sediment was superior to that from the mangrove sediment in terms of electrogenic activity when evaluated by chronoamperometry, and was chosen for further characterisation. …”
Get full text

Long contraction scour by Koh, Chun Wei

“…Using the incomplete self-similarity method and regression analysis of the database, a predictive scour depth equation was proposed which is suitable for applications with uniform and non-uniform sediments. It was found that the maximum scour depth in a long contraction depends mainly on the effect of the densimetric Froude number (Fo,d84), width ratio of the uncontracted to the contracted channel (B1/B2), sediment gradation (σg), and the relative sediment size (d84/h1). …”
Get full text

Scour below a non-full flowing rectangular culvert outlet by Tan, Bei'er.

“…The effects of scour on the sediment bed were visible as soon as water is being channeled from the reservoir and out of rectangular channel. …”
Get full text

Maxwell-type models for the effective thermal conductivity of a porous material with radiative transfer in the voids by Kiradjiev, KB, Halvorsen, SA, Van Gorder, RA, Howison, SD

“…In the high-temperature regime, radiative transfer within voids strongly influences the thermal conductivity of the bulk material. …”

Drug interaction between acetyltanshinone IIA and rapamycin in breast cancer cells by Wong, De Pin

“…Developing in vitro drug combination study is essential for the development of new and effective combination regimens. In this project, the objective is to investigate the synergistic potential between two anti breast cancer agent, rapamycin and acetyltanshinone IIA (ATA) in breast cancer cells. …”
Get full text

Using Sequenom to identify KRAS mutations in an Asian cohort of ovarian mucinous cancer by Tiong, Wen Ning

“…While there are distinct differences between mucinous epithelial ovarian cancer (mEOC) and the other subtypes of EOC, a standard treatment regimen is followed for all EOC histotypes. KRAS mutations have been observed to occur in relatively high frequencies of 50-60% in mEOC but not in other subtypes of EOC in at least three clinical studies. …”
Get full text

Development of a powermeter for a bicycle – I by Pillarisetty Venkata Pranav

“…More than just being a mode of transportation, bicycling has caught on as a competitive sport in many parts of the world and as an exercise regimen by a sizeable fraction of the global population. …”
Get full text

First-line chemotherapy for advanced ovarian cancer: paclitaxel, cisplatin and the evidence by Sandercock, J, Parmar, MKB, Torri, V

“…Two of the reported trials (GOG-111 and the Intergroup trial) provide clear evidence that cisplatin combined with paclitaxel is a more effective regimen than one using the same dose of cisplatin combined with cyclophosphamide. …”

Dynamic properties of high-Tc superconducting nano-junctions made with a focused helium ion beam by Couëdo, François, Amari, Paul, Feuillet-Palma, Cheryl, Ulysse, Christian, Srivastava, Yogesh Kumar, Singh, Ranjan, Bergeal, Nicolas, Lesueur, Jérôme

“…At lower temperature and for the highest He irradiation dose, the shot noise contribution must also be taken into account when approaching the tunneling regime. We conclude that these Josephson nano-junctions present the lowest noise level possible, which makes them very promising for future applications in the microwave and terahertz regimes.…”
Get full text

Myanmar in Eu-Asean relations by Magnus Petersson

“…A rather skeptical view is emphasized on the ‘ASEAN Way’ in dealing with the military regime, and for the overall political dialogue with the European Union.…”
Get full text

Targeted hematopoietic stem cell depletion through SCF-blockade by Chan, Yan Y., Ho, Pui Y., Dib, Carla, Swartzrock, Leah, Rayburn, Maire, Willner, Hana, Ko, Ethan, Ho, Katie, Down, Julian D., Wilkinson, Adam C., Nakauchi, Hiro, Denis, Morgane, Cool, Taylor, Czechowicz, Agnieszka

“…Abstract Background Hematopoietic stem cell transplantation (HSCT) is a curative treatment for many diverse blood and immune diseases. However, HSCT regimens currently commonly utilize genotoxic chemotherapy and/or total body irradiation (TBI) conditioning which causes significant morbidity and mortality through inducing broad tissue damage triggering infections, graft vs. host disease, infertility, and secondary cancers. …”
Get full text

Numerical modeling of the morphological change in Lhok Nga, west Banda Aceh, during the 2004 Indian Ocean tsunami : understanding tsunami deposits using a forward modeling method by Li, Linlin, Qiu, Qiang, Huang, Zhenhua

“…We also discussed the effects of sediment supplies and the constraints that can be put on the earthquake parameters using the information derived from tsunami deposits. …”
Get full text
Get full text

Topological effects on the magnetoconductivity in topological insulators by Sacksteder, Vincent E., Arnardottir, Kristin Bjorg, Kettemann, Stefan, Shelykh, Ivan A.

“…In this wrapped regime the magnetoconductivity's dependence on temperature, typically 1/T2 in 2-DEGs, disappears. …”
Get full text
Get full text

Stress evolution of GaN/AlN heterostructure grown on 6H-SiC substrate by plasma assisted molecular beam epitaxy by Agrawal, Manvi, Ravikiran, Lingaparthi, Dharmarasu, Nethaji, Radhakrishnan, K., Karthikeyan, Giri Sadasivam, Zheng, Yuanjin

“…GaN/AlN structure is found to form buried cracks when AlN is grown in the intermediate growth regime(III/V∼1)and GaN is grown under N-rich growth regime (III/V<1). …”
Get full text
Get full text

Shedding Light on Chemoresistance: The Perspective of Photodynamic Therapy in Cancer Management by Viana Cabral, Fernanda, Quilez Alburquerque, Jose, Roberts, Harrison James, Hasan, Tayyaba

“…Photodynamic therapy (PDT) has emerged as a promising photochemistry-based approach to address chemoresistance in cancer regimens. PDT not only induces cell death but also primes surviving cells, enhancing their susceptibility to subsequent therapies. …”
Get full text

Spatiotemporal signatures of elastoinertial turbulence in viscoelastic planar jets by Yamani, Sami, Raj, Yashasvi, Zaki, Tamer A., McKinley, Gareth H., Bischofberger, Irmgard

“…We show how fluid elasticity has a nonmonotonic effect on the jet stability depending on its magnitude, creating two distinct regimes in which elastic effects can either destabilize or stabilize the jet. …”
Get full text

Performance of epoxy-based self-healing mortar by Ariffin, Nur Farhayu

Get full text

Disposition kinetics of tylosin administered intravenously and intramuscularly in Desert Sheep and Nubian Goats by Taha, A.A., Elsheikh, H.A., Khalafalla, A.E., Osman, I. A. M., Abdullah, A. Salam

“…The present study has shown that, despite the significant differences in some of the drug pharmacokinetic parameters between sheep and goats for the i.v. route, identical intravenous and intramuscular dosage regimens of tylosin may be recommended for the two species.…”
Get full text