Somatic gene mutation patterns and burden influence outcomes with enasidenib in relapsed/refractory IDH2-mutated AML by Risueño, A, See, WL, Bluemmert, I, de Botton, S, DiNardo, CD, Fathi, AT, Schuh, AC, Montesinos, P, Vyas, P, Prebet, T, Gandhi, A, Hasan, M

“…We recently reported results from the phase 3 IDHENTIFY trial (NCT02577406) showing improved response rates and event-free survival with enasidenib monotherapy compared with conventional care regimens (CCR) in heavily pretreated, older patients with late-stage R/R AML bearing IDH2 mutations. …”

Varieties of indoctrination: the politicization of education and the media around the world by Neundorf, A, Nazrullaeva, E, Northmore-Ball, K, Tertytchnaya, KT, Kim, W

“…For many decades, scholars assumed voluntary compliance and citizens’ commitment to a regime’s principles and values to be critical for regime stability. …”

Dip coating of bidisperse particulate suspensions by Jeong, Deok-Hoon, Lee, Michael Ka Ho, Thiévenaz, Virgile, Bazant, Martin Z, Sauret, Alban

“…We also characterize the intermediate regime that consists of a heterogeneous coating layer and where the composition of the film is different from the composition of the bath. …”
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Enhancing quantum synchronization through homodyne measurement, noise, and squeezing by Shen, Yuan, Soh, Hong Yi, Fan, Weijun, Kwek, Leong Chuan

“…Homodyne measurement emerges as one of the successful candidates for this task but preferably in the semiclassical regime. In our work, we focus on the phase synchronization of a harmonic-driven quantum Stuart-Landau oscillator and show that the enhancement induced by homodyne measurement persists into the quantum regime. …”
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A review of offshore decommissioning regulations in five countries – strengths and weaknesses by Fam, Mei Ling, Konovessis, Dimitris, Tan, Hoon Kiang, Ong, Lin Seng

“…Major differences lie in two overarching philosophies of the framework - a prescriptive regime versus a goal-setting regime. Other decommissioning aspects appear to attract increasing attention, such as in expanding clarity on in situ decommissioning, residual liabilities, optimising finance related issues of decommissioning and offshore to onshore waste movement. …”
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The effect of salt on oligocation-induced chromatin condensation by Korolev, Nikolay, Zhao, Yongqian, Allahverdi, Abdollah, Eom, Khee Dong, Nordenskiöld, Lars, Tam, James P.

“…In the salt-dependent regime EC50 rises sharply with increase of CKCl. Increase of ligand charge shifts the transition from the salt-independent to salt-dependent regime to higher salt. …”
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Genomic profiling of mycobacterium tuberculosis strains, Myanmar by Aung, Htin Lin, Nyunt, Wint Wint, Fong, Yang, Biggs, Patrick J., Winkworth, Richard C., Lockhart, Peter J., Yeo, Tsin Wen, Hill, Philip C., Cook, Gregory M., Aung, Si Thu

“…Introducing new oral drugs to replace those currently used in treatment regimens for multidrug-resistant TB will also be useful for treating TB in Myanmar.…”
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Light-matter interactions in atomically thin transition metal dichalcogenides by Zhao, Jiaxin

“…The system working in the strong coupling regime exhibits a clear anti-crossing behavior with a large Rabi splitting around 37 meV. …”
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Psychosocial predictors of self-reported medical adherence in patients with heart failure over 6 months : an examination of the influences of depression, self-efficacy, social supp... by Shen, Biing-Jiun, Maeda, Uta

“…Background Poor adherence to medical regimens is a serious problem that interferes with heart failure (HF) patients’ disease management and contributes to poor clinical outcomes. …”
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Clostridium difficile bacteriophage finding under normal and iron-limited conditions for the isolation of potential siderophore receptor-specific phages by Lim, Edsel Yong Xun

“…Phage therapy, known for its specificity of action, has emerged as a promising candidate for combating CDI, offering the potential to circumvent gut microbiome dysbiosis associated with conventional antibiotic regimens. However, research on Clostridium difficile (C. difficile) phage hunting has been relatively limited. …”
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Exploring the therapeutic potential of 5-fluorouracil-loaded calcium carbonate nanoparticles combined with natural compound thymoquinone for colon cancer treatment by Deng, Xi, Yang, Zhongming, Chan, Kim Wei, Abu Bakar, Md Zuki

“…These results provide evidence for 5FU-CaCO3np as a novel regimen against colon cancer. Combining 5FU-CaCO3np and TQ may offer a new perspective for colon cancer therapy.…”
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Rifaximin potentiates clarithromycin against Mycobacterium abscessus in vitro and in zebrafish by Goh, Boon Chong, Larsson, Simon, Dam, Linh Chi, Ling, Sharon Yan Han, Chua, Patrina Wei Lin, Abirami, R., Singh, Samsher, Ong, Ernest Jun Long, Teo, Jeanette W. P., Ho, Peiying, Ingham, Philip William, Pethe, Kevin, Dedon, Peter C.

“…Because of its extensive innate resistance to numerous antibiotics, treatment options are limited, often resulting in poor clinical outcomes. Current treatment regimens usually involve a combination of antibiotics, with clarithromycin being the cornerstone of NTM treatments.…”
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Origin of residual strain in heteroepitaxial films by Postelnicu, Eveline, Wen, Rui-Tao, Ma, Danhao, Wang, Baoming, Wada, Kazumi, Michel, Jurgen, Kimerling, Lionel C

“…The model is expressed in terms of three regimes: (1) misfit control for the low temperature growth regime at 400 °C; (2) point defect control via annealing in the point defect recovery regime at 500–650 °C; and (3) thermal expansion control for growth or anneal at T > 650 °C in the dislocation recovery regime. …”
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Dynamics of the sub-Ohmic spin-boson model : a comparison of three numerical approaches by Yao, Yao, Duan, Liwei, Lü, Zhiguo, Wu, Chang-Qin, Zhao, Yang

“…The Davydov D1 ansatz and the time-dependent density matrix renormalization group can both be reliably employed in the weak-coupling regime, while the former is also valid in the strong-coupling regime as judged by how faithfully the trial state follows the Schrodinger ¨ equation. …”
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Designing novel multilayered nanocomposites for high-performance coating materials with online strain monitoring capability by Anwar Ali, Hashina Parveen, Radchenko, Ihor, Zhou, Jiahui, Qing, Liu, Budiman, Arief

“…These materials can withstand very high strains in the elastic regime without any inelastic relaxation due to plasticity or fracture compared to its bulk counterparts. …”
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Hobbes and the tragedy of democracy by Holman, Christopher

“…For Hobbes these two conditions combine to render democracy a tragic regime. Democracy is tragic to the extent that it must be a regime of self-limitation, there existing no ethical standard external to society that may intervene so as to guide our political self-activity, and yet the structure of deliberation in democratic assemblies tends to render such self-limitation impossible. …”
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Laser-induced reduced-graphene-oxide micro-optics patterned by femtosecond laser direct writing by Low, Mun Ji, Lee, Hyub, Lim, Joel Chin Huat, Suchand Sandeep, Chandramathi Sukumaran, Murukeshan, Vadakke Matham, Kim, Seung-Woo, Kim, Young-Jin

“…By extensive parametric control of average power (10–120 mW), pulse repetition rate (1–500 kHz) and scan speed (1–100 mm/s) in FsLDW, ultra-thin micro-optics were patterned at three patterning regimes: non-thermal photoreduction regime, thermal photoreduction regime, and ablation regime. …”
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Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial by McIlroy, G, Gaskell, C, Jackson, A, Yafai, E, Tasker, R, Thomas, C, Fox, S, Boucher, R, Ghebretinsea, F, Harrison, C, Mead, AJ, McMullin, MF

“…FEDORA uses a within-patient dose escalation regimen to ensure each patient reaches a personalised dose combination that is acceptable. …”

May measurement month 2022: an analysis of blood pressure screening findings from Sierra Leone by Jalloh, MB, Williams, CEE, Jegede, OG, Malijan, GMB, Naveed, A, Kanu, A, Bah, AK, Jalloh, F, Jalloh, A, Faulkner, MMJ, Agboola, K, Baldeh, M, Russell, JBW, Oladapo, OO

“…Notably, 42.9% of the participants with known hypertension did not adhere to their antihypertensive medication regimen, citing cost, availability, side effects, and forgetfulness as common reasons. …”

WTO membership and its critical importance to China. by Wong, Chak Mun.

“…For the political regime in China, WTO membership is crucial to the realisation of its vision for 21st Century China. …”
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