Somatic gene mutation patterns and burden influence outcomes with enasidenib in relapsed/refractory IDH2-mutated AML by Risueño, A, See, WL, Bluemmert, I, de Botton, S, DiNardo, CD, Fathi, AT, Schuh, AC, Montesinos, P, Vyas, P, Prebet, T, Gandhi, A, Hasan, M

“…We recently reported results from the phase 3 IDHENTIFY trial (NCT02577406) showing improved response rates and event-free survival with enasidenib monotherapy compared with conventional care regimens (CCR) in heavily pretreated, older patients with late-stage R/R AML bearing IDH2 mutations. …”

The changing nature of Chinese business in Africa : the case of Cape Verde by Horta, Loro

“…Chinese state companies are usually singled out for criticism in the West due to their links with despotic African regimes all for the sake of profit. The nature of Chinese business in Africa is however becoming more complex.…”
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No Shangri-La for North Korea by Samaniego, Catherine

“…Kim Jong-un should expect to see his regime’s political leverage in Northeast Asia gradually reduced, while its biggest ally, China, remains preoccupied with its own domestic concerns.…”
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Our weapons, our problem: arms exports, democracy and civil society in Brazil and the UK by de Moraes, RF

“…Next, I examine why and how the governments of these two countries sought to export their practices to the rest of the world or opted to join international regimes.</p>…”

Genomic profiling of mycobacterium tuberculosis strains, Myanmar by Aung, Htin Lin, Nyunt, Wint Wint, Fong, Yang, Biggs, Patrick J., Winkworth, Richard C., Lockhart, Peter J., Yeo, Tsin Wen, Hill, Philip C., Cook, Gregory M., Aung, Si Thu

“…Introducing new oral drugs to replace those currently used in treatment regimens for multidrug-resistant TB will also be useful for treating TB in Myanmar.…”
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Emergent Democracy by Ito, Joichi

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Psychosocial predictors of self-reported medical adherence in patients with heart failure over 6 months : an examination of the influences of depression, self-efficacy, social supp... by Shen, Biing-Jiun, Maeda, Uta

“…Background Poor adherence to medical regimens is a serious problem that interferes with heart failure (HF) patients’ disease management and contributes to poor clinical outcomes. …”
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Clostridium difficile bacteriophage finding under normal and iron-limited conditions for the isolation of potential siderophore receptor-specific phages by Lim, Edsel Yong Xun

“…Phage therapy, known for its specificity of action, has emerged as a promising candidate for combating CDI, offering the potential to circumvent gut microbiome dysbiosis associated with conventional antibiotic regimens. However, research on Clostridium difficile (C. difficile) phage hunting has been relatively limited. …”
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Exploring the therapeutic potential of 5-fluorouracil-loaded calcium carbonate nanoparticles combined with natural compound thymoquinone for colon cancer treatment by Deng, Xi, Yang, Zhongming, Chan, Kim Wei, Abu Bakar, Md Zuki

“…These results provide evidence for 5FU-CaCO3np as a novel regimen against colon cancer. Combining 5FU-CaCO3np and TQ may offer a new perspective for colon cancer therapy.…”
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Rifaximin potentiates clarithromycin against Mycobacterium abscessus in vitro and in zebrafish by Goh, Boon Chong, Larsson, Simon, Dam, Linh Chi, Ling, Sharon Yan Han, Chua, Patrina Wei Lin, Abirami, R., Singh, Samsher, Ong, Ernest Jun Long, Teo, Jeanette W. P., Ho, Peiying, Ingham, Philip William, Pethe, Kevin, Dedon, Peter C.

“…Because of its extensive innate resistance to numerous antibiotics, treatment options are limited, often resulting in poor clinical outcomes. Current treatment regimens usually involve a combination of antibiotics, with clarithromycin being the cornerstone of NTM treatments.…”
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Varieties of indoctrination: the politicization of education and the media around the world by Neundorf, A, Nazrullaeva, E, Northmore-Ball, K, Tertytchnaya, KT, Kim, W

“…For many decades, scholars assumed voluntary compliance and citizens’ commitment to a regime’s principles and values to be critical for regime stability. …”

Non-newtonian fluids and droplets in microchannels by Huang, Yi

“…Different droplet formation regimes and the impact of AC electric field were considered when the measurements were conducted. …”
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Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial by McIlroy, G, Gaskell, C, Jackson, A, Yafai, E, Tasker, R, Thomas, C, Fox, S, Boucher, R, Ghebretinsea, F, Harrison, C, Mead, AJ, McMullin, MF

“…FEDORA uses a within-patient dose escalation regimen to ensure each patient reaches a personalised dose combination that is acceptable. …”

May measurement month 2022: an analysis of blood pressure screening findings from Sierra Leone by Jalloh, MB, Williams, CEE, Jegede, OG, Malijan, GMB, Naveed, A, Kanu, A, Bah, AK, Jalloh, F, Jalloh, A, Faulkner, MMJ, Agboola, K, Baldeh, M, Russell, JBW, Oladapo, OO

“…Notably, 42.9% of the participants with known hypertension did not adhere to their antihypertensive medication regimen, citing cost, availability, side effects, and forgetfulness as common reasons. …”

Deep neural networks have an inbuilt Occam’s razor by Mingard, C, Rees, H, Valle-Pérez, G, Louis, AA

“…The prior over functions is determined by the network architecture, which we vary by exploiting a transition between ordered and chaotic regimes. For Boolean function classification, we approximate the likelihood using the error spectrum of functions on data. …”

Profiting from prestige: the political economy of mega-events in Azerbaijan by Laporte, J

“…By problematising the direction of causality between mega-events and rentseeking behaviour, this analysis expands current theories on states’ motivations for hosting these events and contributes to existing understandings about how these proceedings serve to support and sustain rentier regimes.…”

Conflict abroad and political trust at home evidence from a natural experiment by Klymak, M, Vlandas, T

“…Further analyses using other surveys and previous conflicts suggest this effect depends on proximity to the conflict and the political regimes of the attacked country. These findings contribute to our understanding of the complex and indirect effects of conflicts on domestic political trust.…”

Predictability of exchange rates with taylor rule fundamentals : evidence from inflation-targeting emerging countries by Alba, Joseph Dennis, Park, Donghyun, Xie, Taojun

“…We investigate the out-of-sample predictability of U.S. dollar exchange rates with Taylor rule fundamentals in thirteen emerging countries with inflation-targeting monetary policy regimes. We find some evidence of out-of-sample exchange rate predictability for Brazil, Czech Republic, Hungary, Philippines, Thailand, and South Africa. …”
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Classification of fixed points of Potts-Bethe mapping of degree four on Q5 by Ahmad, Mohd. Ali Khameini, Murat Alp, Murat Alp, Mohd. Azahari, Mohammad Azim, Embong, Ahmad Fadillah

“…In this paper, the Potts–Bethe mapping of degree four is con-sidered over the field Q5 of 5-adic numbers. In some regimes (a condition appear in the study of p-adic Potts model), the fixed points are found and their stability are determined. …”
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Evaluation of subconjunctival liposomal steroids for the treatment of experimental uveitis by Wong, Chee Wai, Czarny, Bertrand, Metselaar, Josbert M., Ho, Candice, Ng, Si Rui, Barathi, Amutha Veluchamy, Storm, Gert, Wong, Tina T.

“…The current gold standard for treatment is topical steroids, but low ocular bioavailability and compliance issues with the intensive dosing regimen limit the efficacy of this treatment. Liposomes as a drug delivery system may help to overcome these problems. …”
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