Investigating the impact of growth arrest mechanisms on tumour growth and responses to radiotherapy and hyperthermia by Colson, C

“…In each regime, we determine the biological processes that may underpin positive and negative treatment outcomes and assess which treatment (RT, HT or RT + HT) and dosing regimen maximise the reduction in tumour burden. …”

The role of SPRTN protease in colorectal cancer chemotherapy by Peron, C

“…The first-line treatment of metastatic colorectal cancer (mCRC) is frequently based on combination chemotherapeutic regimens, where 5-fluorouracil is either associated with irinotecan (FOLFIRI) or oxaliplatin (FOLFOX). …”

Phonological analysis of syllabic changes of Arabic loan verbs by Muhaimin Syaqiq Mawaridi, Abdul Azim Mohamad Isa, Lutfi Hassan

“…The reduction of syllable segments refers to a segmental reduction in the first, second or third syllable. …”
Get full text

Behaviour of joints in tunnel linings by Alevey, Niall Mac, Ashraf Mohamed Hefny

“…Precast concrete tunnel segments are used extensively to construct tunnel linings. …”
Get full text

Part I: Synthesis of sex pheromone of the pine sawfly, Macrodiprion Nemoralis. Part II: Synthetic studies towards the total synthesis of iriomoteolide-1a by Chin, Yen Jin

“…Conjugate addition of Grignard reagents to α,β-unsaturated esters is one of the most convergent strategies for the construction of C–C bonds. …”
Get full text

Distinct Circle of Willis anatomical configurations in healthy preterm born adults: a 3D time-of-flight magnetic resonance angiography study by Greggio, J, Malamateniou, C, Baruteau, KP, Reyes-Aldasoro, CC, Huckstep, OJ, Francis, JM, Williamson, W, Leeson, P, Lewandowski, AJ, Lapidaire, W

“…In contrast, preterm females showed higher odds of a group 4a variant (circles with one or more accessory segments, without any absent segments) in comparison to their full-term counterparts (p = 0.020). …”

Microbially induced calcite precipitation in residual soil improvement by Murtala Umar

Get full text

Estimating evolutionary and demographic parameters via ARG-derived IBD by Huang, Z, Kelleher, J, Chan, Y, Balding, D

“…Inference of evolutionary and demographic parameters from a sample of genome sequences often proceeds by first inferring identical-by-descent (IBD) genome segments. By exploiting efficient data encoding based on the ancestral recombination graph (ARG), we obtain three major advantages over current approaches: (i) no need to impose a length threshold on IBD segments, (ii) IBD can be defined without the hard-to-verify requirement of no recombination, and (iii) computation time can be reduced with little loss of statistical efficiency using only the IBD segments from a set of sequence pairs that scales linearly with sample size. …”

Variational mesh decomposition by Zhang, Juyong, Zheng, Jianmin, Wu, Chunlin, Cai, Jianfei

“…The problem of decomposing a 3D mesh into meaningful segments (or parts) is of great practical importance in computer graphics. …”
Get full text
Get full text

The impact of evolving SARS-CoV-2 mutations and variants on COVID-19 vaccines by McLean, Gary R., Kamil, Jeremy, Lee, Benhur, Moore, Penny, Schulz, Thomas F., Muik, Alexander, Sahin, Ugur, Tureci, Ozlem, Pather, Shanti

“…Although data on the effectiveness of the primary regimen against omicron (B.1.1.529) are limited, booster programs using mRNA vaccines have been shown to restore protection against infection and symptomatic disease (regardless of the vaccine used for the primary regimen) and maintain high effectiveness against hospitalization. …”
Get full text

Synthesis and properties of core-shell structure of triangular Ag@Au by Satkunarajah Pratheepan.

“…These factors include, concentration of reagents, edge length of the prisms, temperature, rate of injection, pH of both the prisms and reagents and the speed of stirring Characterization is performed using UV Vis spectroscopy and Transmission Electron Microscopy, at various intervals during and after the coating process to study the effect of the factors mentioned earlier. …”
Get full text

Optimising statistical methodologies for estimating antimalarial efficacy for uncomplicated Plasmodium falciparum malaria by Dahal, P

“…For dihydroartemisinin-piperaquine (DP) regimen, a study with 42 day follow-up was estimated to miss 47% [95% CI: 19 – 90%] of the treatment failures in those who were adequately dosed. …”

Modelling the rheology of living cell cytoplasm: poroviscoelasticity and fluid-to-solid transition by Thekkethil, Namshad, Köry, Jakub, Guo, Ming, Stewart, Peter S., Hill, Nicholas A., Luo, Xiaoyu

“…Baseline simulations (neglecting the viscosity of the cytosol) indicate that the system exhibits seven different regimes across the parameter space spanned by the viscoelastic relaxation timescale of the cytoskeleton and the poroelastic diffusion timescale; these regimes agree qualitatively with experimental measurements. …”
Get full text

Development of a point-of-care (POC) diagnostic system by Lee, Shinhan.

“…The project was successfully demonstrated with the first working prototype demo system that incorporate the iPhone with App for imaging and communication and the POC system design that allows the transport of bio-samples and reagents through the reaction chambers attached with the LSPR chips in the microfluidic testing cartridge. …”
Get full text

Establishing an antibody mimetic applicable to targeting in the gastrointestinal tract by Wicke, NS

“…The upper gastrointestinal tract, however, rapidly inactivates protein-based targeting reagents. Compared to injections, oral administration of protein therapies is favourable for treating gastrointestinal disease. …”

Spatio temporal traffic pediction for a large-scale road network by Krishnamoorthy, Nardana

“…The road segments belonging to one of these clusters were then tested. …”
Get full text

Thermoplastic polymer nanocomposites based on polydopamine-coated clay : preparation, structures and properties by Phua, Si Lei

“…This strong interfacial interaction between D-clay and hard segments not only facilitates the stress transfer across the filler and polymer matrix, but also acts as nucleating agent for hard segment crystallization, leading to higher hard segment crystallinity. …”
Get full text

An investigation of friction-based tendon sheath model appropriate for control purposes by Tjahjowidodo, Tegoeh, Lau, Michael Wai Shing, Phee, Soo Jay, Do, T. N.

“…A new dynamic friction model that allows accurate description of friction lag and hysteresis behavior in two regimes, i.e. presliding and sliding regimes, for a sheath in arbitrary configuration such as helical and spatial shape has been developed. …”
Get full text
Get full text

Reduction of dimensionality of a cellular actuator array for driving a robotic hand by Cho, Kyu-Jin, Ph. D. Massachusetts Institute of Technology

Get full text

Asymptotic analysis of deep residual networks by Cont, R, Rossier, A, Xu, R

“…We first show the existence of scaling regimes for trained weights markedly different from those implicitly assumed in the neural ODE literature. …”