Hollow microcapsules as periocular drug depot for sustained release of anti-VEGF protein by Radhakrishnan, Krishna, Vincent, Anita, Joseph, Rini Rachel, Moreno, Miguel, Dickescheid, Andreas, Agrawal, Rupesh, Venkatraman, Subbu S.

“…The current treatment regimen for such diseases involves repeated intravitreal injections of anti- Vascular Endothelial Growth Factor (VEGF) proteins. …”
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Elucidating the role of metabolic changes in modulating cell fate following treatment with anti-mitotic drugs by Wong, Alex Xing Fah

“…Better understanding of the cellular pathways underlying this escape from antimitotic drug-induced cell death, known as mitotic slippage, is crucial for development of combinatorial therapies that can enhance existing treatment regimen in patients. Mitotic slippage describes a phenomenon where cells escape mitotic arrest and cell death following treatment with anti-mitotic drugs, and "slip" into interphase without proper chromosome segregation and cytokinesis. …”
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Evaluating new malaria vaccine candidates by Noé, A

“…Liver-resident memory CD8+ T cells (TRM) are necessary for protection against rodent malaria by this vaccine regimen. Ultimately, to most faithfully assess immunological responses by these local, specialised, hepatic T cells, periodic liver sampling is necessary. …”

Managing oil palm plantations more sustainably : large-scale experiments within the Biodiversity and Ecosystem Function in Tropical Agriculture (BEFTA) Programme by Luke, Sarah H., Advento, Andreas Dwi, Aryawan, Anak Agung Ketut, Adhy, Dwi Nugroho, Ashton-Butt, Adham, Barclay, Holly, Dewi, Jassica Prajna, Drewer, Julia, Dumbrell, Alex J., Edi, Eycott, Amy E., Harianja, Martina F., Hinsch, Julie K., Hood, Amelia S. C., Kurniawan, Candra, Kurz, David J., Mann, Darren J., Matthews Nicholass, Kirsty J., Naim, Mohammad, Pashkevich, Michael D., Prescott, Graham W., Ps, Sudharto, Pujianto, Purnomo, Dedi, Purwoko, Rizky Rajabillah, Putra, Syafrisar, Rambe, T. Dzulfikar S., Soeprapto, Spear, Dakota M., Suhardi, Tan, David J. X., Tao, Hsiao-Hang, Tarigan, Ribka Sionita, Wahyuningsih, Resti, Waters, Helen S., Widodo, Rudi Harto, Whendy, Woodham, Christopher R., Caliman, Jean-Pierre, Slade, Eleanor M., Snaddon, Jake L., Foster, William A., Turner, Edgar C.

“…The Programme has established four major components: (1) assessing variability within the plantation under business-as-usual conditions; (2) the BEFTA Understory Vegetation Project, which tests the effects of varying herbicide regimes; (3) the Riparian Ecosystem Restoration in Tropical Agriculture (RERTA) Project, which tests strategies for restoring riparian habitat; and (4) support for additional collaborative projects within the Programme landscape. …”
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GPU-based commonsense reasoning for real-time query answering and multimodal analysis by Tran, Ha Nguyen

“…Secondly, in order to reason and retrieve information on rule-based knowledge bases, the thesis introduces gSparql, a fast and scalable inference and querying method on mass-storage RDF data with rule-based entailment regimes. Our approach accepts different rulesets and executes the reasoning process at query time when the inferred triples are determined by the set of triple patterns defined in the query. …”
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Exploring the therapeutic potential of 5-fluorouracil-loaded calcium carbonate nanoparticles combined with natural compound thymoquinone for colon cancer treatment by Deng, Xi, Yang, Zhongming, Chan, Kim Wei, Abu Bakar, Md Zuki

“…These results provide evidence for 5FU-CaCO3np as a novel regimen against colon cancer. Combining 5FU-CaCO3np and TQ may offer a new perspective for colon cancer therapy.…”
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Light-matter interactions in atomically thin transition metal dichalcogenides by Zhao, Jiaxin

“…The system working in the strong coupling regime exhibits a clear anti-crossing behavior with a large Rabi splitting around 37 meV. …”
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Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial by McIlroy, G, Gaskell, C, Jackson, A, Yafai, E, Tasker, R, Thomas, C, Fox, S, Boucher, R, Ghebretinsea, F, Harrison, C, Mead, AJ, McMullin, MF

“…FEDORA uses a within-patient dose escalation regimen to ensure each patient reaches a personalised dose combination that is acceptable. …”

May measurement month 2022: an analysis of blood pressure screening findings from Sierra Leone by Jalloh, MB, Williams, CEE, Jegede, OG, Malijan, GMB, Naveed, A, Kanu, A, Bah, AK, Jalloh, F, Jalloh, A, Faulkner, MMJ, Agboola, K, Baldeh, M, Russell, JBW, Oladapo, OO

“…Notably, 42.9% of the participants with known hypertension did not adhere to their antihypertensive medication regimen, citing cost, availability, side effects, and forgetfulness as common reasons. …”

Towards electrically injected colloidal semiconductor lasers by Thung, Yi Tian

“…The NPL-VCSEL demonstrated a low lasing threshold of 21.6 W cm-2 with a single-mode Q-factor of 11800 under continuous-wave (cw) excitation, with good agreement between the cw-pumped lasing spectra and the ps pulse-pumped lasing spectra. to highlighting the NPL-VCSEL’s robustness under different optical pumping regimes, I demonstrated the NPL-VCSEL’s performance under continuous wave optical pump, affirming the suitability of the colloidal NPLs as the preferred gain medium to realize the desired electrically injected colloidal semiconductor lasers. …”
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Studies on plasma assisted molecular beam epitaxial growth of GaN-based multilayer heterostructures on Si for photodetector application by Zheng, Yi

“…Tunability of band gap and the possibility of formation of heterostructures with group III-nitride materials allow the design of complex structures to detect both UV and infra-red (IR) spectral regimes (multi band) on a single chip. By growing AlGaN/GaN multiple quantum well layers, IR detector can also be obtained, which means IR and UV detector can be achieved using the same material. …”
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Evaluation of subconjunctival liposomal steroids for the treatment of experimental uveitis by Wong, Chee Wai, Czarny, Bertrand, Metselaar, Josbert M., Ho, Candice, Ng, Si Rui, Barathi, Amutha Veluchamy, Storm, Gert, Wong, Tina T.

“…The current gold standard for treatment is topical steroids, but low ocular bioavailability and compliance issues with the intensive dosing regimen limit the efficacy of this treatment. Liposomes as a drug delivery system may help to overcome these problems. …”
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Repurposing nitroxoline to address antibiotic resistance in the production of poultry for consumption by Zhou, Y

“…<em>In-vivo</em> evaluation (Chapter 5) established an optimal dosage regimen (100 mg/kg of NTX in feed) for treating <em>Salmonella</em> infections in poultry without promoting the development of resistance. …”

Cytisine versus varenicline for smoking cessation in a primary care setting: a randomized non-inferiority trial by Oreskovic, T, Percac-Lima, S, Ashburner, JM, Tiljak, H, Rifel, J, Klemenc Ketiš, Z, Oreskovic, S

“…Given the much lower cost of cytisine treatment, its lower rate of adverse events, and higher feasibility (but its likely lower effectiveness with the standard dosage regimen), future analyses should assess the cost-effectiveness of the two treatments for health policy considerations.…”

STandards for reporting interventions in clinical trials of tuina/massage (STRICTOTM): extending the CONSORT statement by Zhang, Xuan, Liang, Feng, Lau, Chung Tai, Chan, Jacky C. P., Wang, Nana, Deng, Jiashuai, Wang, Juan, Ma, Yanfang, Zhong, Linda Lidan, Zhao, Chen, Yao, Liang, Wu, Taixiang, Lyu, Aiping, Tian, Guihua, Shang, Hongcai, Miao, Jiangxia, Bian, Zhaoxiang

“…Results: A checklist of seven items (namely Tuina/Massage rationale, details of Tuina/Massage, intervention regimen, other components of the intervention, Tuina/Massage provider background, control or comparator interventions, and precaution measures), and 16 subitems were developed. …”
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Next generation design of floating systems for coastal solar farms by Bi, Cheng

“…In the single-barrier-platform system, the barrier is installed in front of the platform, and significant reduction in platform displacement can be achieved when the barrier is in the membrane-like hydroelastic regime with relatively high rigidity and has a penetration more than 40% of water depth. …”
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EU competition law : a roadmap for ASEAN? by Valockova, Barbora

“…The European Union’s competition policy and legal regime is instrumental in the functioning of the single market in the EU. …”
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Dynamical blockade in a single-mode bosonic system by Ghosh, Sanjib, Liew, Timothy Chi Hin

“…We find that the underlying mechanism for the blockade is general, enhancing antibunching in the strongly nonlinear regime and inducing it in the weakly nonlinear regime, without fine-tuning the system parameters. …”
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Maxwell-type models for the effective thermal conductivity of a porous material with radiative transfer in the voids by Kiradjiev, KB, Halvorsen, SA, Van Gorder, RA, Howison, SD

“…In the high-temperature regime, radiative transfer within voids strongly influences the thermal conductivity of the bulk material. …”

Enhancing quantum synchronization through homodyne measurement, noise, and squeezing by Shen, Yuan, Soh, Hong Yi, Fan, Weijun, Kwek, Leong Chuan

“…Homodyne measurement emerges as one of the successful candidates for this task but preferably in the semiclassical regime. In our work, we focus on the phase synchronization of a harmonic-driven quantum Stuart-Landau oscillator and show that the enhancement induced by homodyne measurement persists into the quantum regime. …”
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