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221
Exploring the moderating role of expressive suppression in the relationship between psychopathy and aggression
Published 2024Subjects: Get full text
Final Year Project (FYP) -
222
Relationships among emotion regulation, depression, anxiety, stress, and physical health-related quality of life in coronary heart disease patients
Published 2020“…Coronary heart disease (CHD) is the third leading cause of death in Singapore. Although emotion regulation is a significant determinant of CHD patient’s quality of life, not many studies have assessed the impact of change in emotion regulation on physical functioning over time. …”
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Final Year Project (FYP) -
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Guiding transition metal-doped hollow cerium tandem nanozymes with elaborately regulated multi-enzymatic activities for intensive chemodynamic therapy
Published 2022“…This work presents a powerful paradigm to achieve intensive NCDT efficacy by simultaneously regulating multi-enzymatic activities of Ce-based nanozymes and perturbing the H2O2 homeostasis in tumor microenvironment.…”
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A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling
Published 2024“…Here we report that high FSS suppresses Smad1/5 by elevating KLF2, which induces the bone morphogenetic protein (BMP) pathway inhibitor, BMP-binding endothelial regulator (BMPER), thereby de-inhibiting Akt. In mice, surgically induced high FSS elevated BMPER expression, inactivated Smad1/5 and induced vessel outward remodeling. …”
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227
Congenital myasthenic syndromes: characterisation of a new animal model, exploring potential novel therapies and assessing the outcome of COVID-19 infection
Published 2024Subjects: “…Allosteric regulation…”
Thesis -
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Identification of potential common cyclic-di-GMP regulated biomarkers among three gram negative bacteria via transcriptomic and metabolomic profiling
Published 2017“…The results indicated that RpoN modulates virulence secretion through a PQS quorum sensing regulator, pqsR. This study provides evidence for the possible detection and diagnosis of biofilm infections in clinical prospective using c-di-GMP regulated metabolites; it also demonstrates the complex connections and regulations among global regulators at the same time.…”
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Thesis -
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Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells
Published 2018“…Here, we report that HIF-2α up-regulates the expression of CD70, a cancer-related surface antigen that improves anchorage-independent growth in cancer cells and is associated with poor clinical prognosis, which can be induced via epigenetic modifications mediated by DNMT1. …”
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Journal Article -
232
Dance battle: power relations within the Singapore dance scene
Published 2024Subjects: Get full text
Final Year Project (FYP) -
233
Learning from the community: iterative co-production of a programme to support the development of attention, regulation and thinking skills in toddlers at elevated likelihood of autism or ADHD
Published 2025“…The logic model for the resultant programme—Supporting Toddlers with a connection to autism or ADHD to develop strong Attention, Regulation and Thinking skills (START)—involves three mechanisms of change: The child has appropriate play-based opportunities to practise EF skills; Parenting behaviours linked to strong EFs are encouraged; Parents are empowered to improve environmental-fit for their child so that EF stressors are reduced.…”
Journal article -
234
Emerging functions of alternative splicing coupled with nonsense-mediated decay
Published 2015Subjects: “…Post-transcriptional regulation of gene expression…”
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Journal Article -
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Controlling fibrous capsule formation through long-term down-regulation of collagen type I (COL1A1) expression by nanofiber-mediated siRNA gene silencing
Published 2013“…In this study, we investigated the efficacy of siRNA–poly(caprolactone-co-ethylethylene phosphate) nanofibers in controlling fibrous capsule formation through the down-regulation of collagen type I (COL1A1) in vitro and in vivo. …”
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Essays in comparative political economy: bureaucracy and participation in policymaking
Published 2021Subjects:Thesis