Supported Lipid Bilayer Platform To Test Inhibitors of the Membrane Attack Complex: Insights into Biomacromolecular Assembly and Regulation by Yorulmaz, Saziye, Jackman, Joshua Alexander, Hunziker, Walter, Cho, Nam-Joon

“…Taken together, the findings in this study outline a biomimetic approach based on supported lipid bilayers to explore the interactions between complement proteins and inhibitors, thereby offering insight into MAC assembly and regulation.…”
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Regulation of Burkholderia cenocepacia biofilm formation by RpoN and the c-di-GMP effector BerB by Fazli, Mustafa, Rybtke, Morten, Steiner, Elisabeth, Weidel, Elisabeth, Berthelsen, Jens, Groizeleau, Julie, Bin, Wu, Zhi, Boo Zhao, Yaming, Zhang, Kaever, Volkhard, Givskov, Michael, Hartmann, Rolf W., Eberl, Leo, Tolker-Nielsen, Tim

“…Knowledge about the molecular mechanisms that are involved in the regulation of biofilm formation is essential for the development of biofilm‐control measures. …”
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Transphobia as a weapon of war: reporting on Russia’s trans community amidst heightened regulation, censorship and propaganda by Sloane, Wendy

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Proteomic and metabolomic analyses of the human adult myocardium reveal ventricle-specific regulation in end-stage cardiomyopathies by Hunter, B, Li, M, Parker, BL, Koay, YC, Harney, DJ, Pearson, E, Cao, J, Chen, GT, Guneratne, O, Smyth, GK, Larance, M, O’Sullivan, JF, Lal, S

“…Constituents of gluconeogenesis, glycolysis, lipogenesis, lipolysis, fatty acid catabolism, the citrate cycle and oxidative phosphorylation were down-regulated in the left ventricle, while glycogenesis, pyruvate and ketone metabolism were up-regulated. …”

Nuclei sorting-based genome-wide CRISPR screens to identify novel regulators of hepatic insulin signalling by Martin Perez, E

“…Using this methodology, we successfully identified two novel positive regulators of hepatic insulin signalling, TMED2 and TMED10.…”

The need for regulation: permissive governance and disproportionate use of live facial recognition technology by the Metropolitan Police Service by Croker, JT

“…The conclusions reached in this thesis call for appropriate and effective regulation and oversight of police use of LFR to ensure rights are protected from unlawful and disproportionate harm.…”

Effects of hormonal regulation on cell number and cell size in determining fruit size: a mini-review by Siti Khadijah A. Karim, Zamri Zainal, Nik Marzuki Sidik

“…This mini-review discussed the interplay among major plant hormones in regulating cell number production and cell size in horticultural plants. …”
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A LDO regulator with weighted current feedback technique for 0.47nF-10nF capacitive load by Tan, Xiao Liang, Chong, Sau Siong, Chan, Pak Kwong, Dasgupta, Uday

“…Besides, it provides good regulator loop gain and fast transient response. Validated by UMC 65 nm CMOS process, the simulation and measurement results have shown that the WCF LDO regulator can operate at a load capacitance (CL) range from 470 pF to 10 nF with only 3.8 pF compensation capacitor. …”
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Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr by Zhang, Yingdan, Chew, Alvin Bing Liang, Wang, Jing, Yuan, Mingjun, Yam, Joey Kuok Hoong, Luo, Dahai, Yang, Liang

“…Here, we identify P. aeruginosa's global virulence factor regulator Vfr as one target of auranofin. We report the mechanistic insights into the inhibitory mechanism of auranofin and gold(I) analogues to Vfr through structural, biophysical, and phenotypic inhibition studies. …”
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A comparison of preterm and full-term infant emotional regulation development through infant-mother affect synchrony by Low, Heather Yee Theng

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Energy level alignment regulation and carrier management in perovskite solar cells with various bandgaps using tailored metal-organic frameworks by Xiao, Bo, Zhang, Wenguang, Xiong, Yuchen, Huang, Yihuai, Huang, Changkai, Qian, Yongxin, Shen, Guibin, Basit, Abdul, Luo, Yubo, Li, Xin, Yang, Junyou

Subjects: “…Energy level alignment regulation…”
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A 0.9-µ A quiescent current output-capacitorless LDO regulator with adaptive power transistors in 65-nm CMOS by Chong, Sau Siong, Chan, Pak Kwong

“…An ultra-low quiescent current output-capacitorless low-dropout (OCL-LDO) regulator with adaptive power transistors technique is presented in this paper. …”
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Empowering student self-regulated learning and science education through ChatGPT: a pioneering pilot study by Ng, Davy Tsz Kit, Tan, Chee Wei, Leung, Jac Ka Lok

“…The experimental group used SRLbot to maintain a regular study habit and facilitate their SRL, while the control group utilized rule-based AI chatbots. …”
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TPPP acts downstream of RhoA-ROCK-LIMK2 to regulate astral microtubule organization and spindle orientation by Heng, Yi-Wen., Lim, Hong-Hwa., Mina, Theresia., Utomo, Prayudi., Zhong, Shaoping., Lim, Chwee-Teck., Koh, Cheng-Gee

“…Surprisingly, LIMK1 and cofilin are not involved downstream of RhoA and ROCK in the regulation of astral microtubule organization. Instead, we find that LIMK2 acts through TPPP in the regulation of astral microtubule organization, whereas both LIMK1 and LIMK2 affect centrosome focusing. …”
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Regulation of mRNA abundance by polypyrimidine tract-binding protein-controlled alternate 5′ splice site choice by Hamid, Fursham M., Makeyev, Eugene V.

“…More generally, these data expand our understanding of AS regulation and uncover a post-transcriptional strategy ensuring co-expression of a subordinate gene with its master regulator through an AS-NMD tracking mechanism.…”
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Treatment with siRNAs is commonly associated with GPX4 up-regulation and target knockdown-independent sensitization to ferroptosis by von Mässenhausen, Anne, Schlecht, Marlena Nastassja, Beer, Kristina, Maremonti, Francesca, Tonnus, Wulf, Belavgeni, Alexia, Gavali, Shubhangi, Flade, Karolin, Riley, Joel S., Zamora Gonzalez, Nadia, Brucker, Anne, Becker, Jorunn Naila, Tmava, Mirela, Meyer, Claudia, Peitzsch, Mirko, Hugo, Christian, Gembardt, Florian, Angeli, Jose Pedro Friedmann, Bornstein, Stefan R., Tait, Stephen W. G., Linkermann, Andreas

“…In contrast, MAVS mediated a noncanonical signal resulting in a prominent increase in mitochondrial ROS levels, and increase in the BACH1/pNRF2 transcription factor ratio and GPX4 up-regulation, which was associated with a 50% decrease in intracellular glutathione levels. …”
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Media regulation in Singapore : empirical study of the instruments of media policy and its efficiency with regard to the attainment of political objectives by Carsten, Gäbel

“…Singapore's government justifies the regulation and control of the media by drawing on the “Developmental Concept”, a variation of authoritarian media theory that delineates the role of the media in developing countries. …”
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N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5 by Zou, Shui, Toh, Joel D. W., Wong, Kendra H. Q., Gao, Yong-Gui, Hong, Wanjin, Woon, Esther C. Y.

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Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development by Zhou, Li, Lim, Mandy Yu Theng, Kaur, Prameet, Saj, Abil, Bortolamiol-Becet, Diane, Gopal, Vikneswaran, Tolwinski, Nicholas, Tucker-Kellogg, Greg, Okamura, Katsutomo

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Two models of dark triad traits and self-regulation dilemma predicting IP theft through self-deception by Yeo, Diana Mui Kheng

“…This study aimed to examine how dark triad personality traits and self-regulation dilemma is related to intellectual property (IP) theft. …”
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