Archaeal proline dehydrogenase from Pyrobaculum aerophilum : sequence comparison. by Kik, Shian Chi.

“…U-96 and L-proline dehydrogenase from Pyrococcus horikoshii with root mean square deviation of 2.043 and 1.983 respectively. …”
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TCR affinity biases Th cell differentiation by regulating CD25, Eef1e1, and Gbp2 by Kotov, Dmitri I., Mitchell, Jason S., Pengo, Thomas, Ruedl, Christiane, Way, Sing Sing, Langlois, Ryan A., Fife, Brian T., Jenkins, Marc K.

“…The affinity of the TCR interaction with p:MHCII plays a role in Th differentiation by mechanisms that are not completely understood. …”
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Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance by Mok, S., Ashley, E. A., Ferreira, P. E., Zhu, L., Lin, Z., Yeo, T., Chotivanich, K., Imwong, M., Pukrittayakamee, S., Dhorda, M., Nguon, C., Lim, P., Amaratunga, C., Suon, S., Hien, T. T., Htut, Y., Faiz, M. A., Onyamboko, M. A., Mayxay, M., Newton, P. N., Tripura, R., Woodrow, C. J., Miotto, O., Kwiatkowski, D. P., Nosten, F., Day, N. P. J., Preiser, P. R., White, N. J., Dondorp, A. M., Fairhurst, R. M., Bozdech, Z.

“…The expression profiles of UPR-related genes also associate with the geographical origin of parasite isolates, further suggesting their role in emerging artemisinin resistance in the Greater Mekong Subregion.…”
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Identification and functional analysis of Git3 G protein-coupled receptors in Ganoderma boninense PER71 by Khairunnisa Hanisah Mohd Daud, Mohd Faizal Abu Bakar, Izwan Bharudin, Shazilah Kamaruddin, Huai, Doris Xia Quay, Farah Diba Abu Bakar, Abdul Munir Abdul Murad

“…G protein-coupled receptors (GPCRs) are integral components of eukaryotic heterotrimeric G proteins, playing crucial roles in detecting extracellular signals and initiating the activity of signaling proteins within cells to activate cellular responses to these signals. …”
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Validating predictive sequence analysis in polyketide stereochemical determination though the synthesis of stambomycin D by Lim, J

“…<p>In recent years, predictive gene sequence analysis of biosynthetic enzymes has emerged as a powerful tool for the stereochemical determination of natural products. …”

Transient transmission of Chikungunya virus in Singapore exemplifies successful mitigation of severe epidemics in a vulnerable population by Hapuarachchi, Hapuarachchige Chanditha, Wong, Wing-Yan, Koo, Carmen, Tien, Wei-Ping, Yeo, Gladys, Rajarethinam, Jayanthi, Tan, Eugene, Chiang, Suzanna, Chong, Chee-Seng, Tan, Cheong-Huat, Tan, Li-Kiang, Ng, Lee Ching

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Genotype-specific expression and NLR repertoire contribute to phenotypic resistance diversity in Plantago lanceolata by Safdari, Pezhman, Höckerstedt, Layla, Brosche, Mikael, Salojärvi, Jarkko, Laine, Anna-Liisa

“…Nucleotide-binding leucine-rich repeat (NLR) genes play an important role in pathogen recognition, downstream defense responses and defense signaling. …”
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The habenula clock influences response to a stressor by Basnakova, Adriana, Cheng, Ruey-Kuang, Chia, Joanne Shu Ming, D'Agostino, Giuseppe, Suryadi, Tan, Germaine Jia Hui, Langley, Sarah Raye, Jesuthasan, Suresh

“…Two-photon calcium imaging indicates a circadian change in spontaneous activity of habenula neurons. To assess the role of this clock, a truncated clocka gene was specifically expressed in the habenula. …”
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Sonodynamic Nano-LYTACs reverse tumor immunosuppressive microenvironment for cancer immunotherapy by Xu, Mengke, Hu, Yuxuan, Wu, Jiayan, Liu, Jing, Pu, Kanyi

“…Extracellular and transmembrane proteins, which account for the products of approximately 40% of all protein-encoding genes in tumors, play a crucial role in shaping the tumor immunosuppressive microenvironment (TIME). …”
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An epigenetic locus associated with loss of smell in COVID-19 by Aslan, Elif Sibel, White, Kenneth, Meral, Gulsen, Akcay, Zeyneb Nur, Altundag, Aytug, Gur, Savas, Dokur, Mehmet, Baktir, Mehmet Akif, Batur, Lutfiye Karcioglu

“…However, the role of epigenetic changes in the development and persistence of smell loss has not been well explored. …”
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Whole genome sequencing and comparative analysis of novel pathogen elizbethkingia anophelis against oxidative stress by Li, Yingying

“…Our study suggests that siderophore production and heme uptake pathways might play essential roles in stress response and virulence of the emerging pathogen E. anophelis.…”
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Detection and characterisation of a sixth Candida auris clade in Singapore: a genomic and phenotypic study by Suphavilai, Chayaporn, Ko, Karrie Kwan Ki, Lim, Kar Mun, Tan, Mei Gie, Boonsimma, Patipan, Chu, Joash Jun Keat, Goh, Sui Sin, Rajandran, Prevena, Lee, Lai Chee, Tan, Kwee Yuen, Bushra Binte Shaik Ismail, Aung, May Kyawt, Yang, Yong, Sim, Jean Xiang Ying, Venkatachalam, Indumathi, Cherng, Benjamin Pei Zhi, Spruijtenburg, Bram, Chan, Kian Sing, Oon, Lynette Lin Ean, Tan, Ai Ling, Tan, Yen Ee, Wijaya, Limin, Tan, Ban Hock, Ling, Moi Lin, Koh, Tse Hsien, Meis, Jacques F., Tsui, Clement Kin Ming, Nagarajan, Niranjan

“…Antifungal susceptibility testing was done and antifungal resistance genes, mating-type locus, and chromosomal rearrangements were characterised from the WGS data of the three investigated isolates. …”
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TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR4 Interacts with WRINKLED1 to mediate seed oil biosynthesis by Kong, Que, Singh, Sanjay K., Mantyla, Jenny J., Pattanaik, Sitakanta, Guo, Liang, Yuan, Ling, Benning, Christoph, Ma, Wei

“…Cross-family transcription factor (TF) interactions play critical roles in the regulation of plant developmental and metabolic pathways. …”
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Proteomic network of antibiotic-induced outer membrane vesicles released by extensively drug-resistant Elizabethkingia anophelis by Chiang, Ming-Hsien, Chang, Fang-Ju, Kesavan, Dinesh Kumar, Vasudevan, Aparna, Xu, Huaxi, Lan, Kuo-Lun, Huang, Shu-Wei, Shang, Hung-Sheng, Chuang, Yi-Ping, Yang, Ya-Sung, Chen, Te-Li

“…E. anophelis harbors multidrug resistance (MDR) genes and is intrinsically resistant to various classes of antibiotics. …”
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Deep sequencing of small RNA facilitates tissue and sex associated microRNA discovery in zebrafish by Vaz, Candida, Wee, Choon Wei, Lee, Gek Ping Serene, Ingham, Philip William, Tanavde, Vivek, Mathavan, Sinnakaruppan

“…Background: The role of microRNAs in gene regulation has been well established. …”
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Morphological multiparameter filtration and persistent homology in mitochondrial image analysis by Chung, Yu-Min, Hu, Chuan-Shen, Sun, Emily, Tseng, Henry C.

“…Using this information, we also develop a connectivity index that describes the morphology of the branching patterns. As proof of concept, we utilize this approach to study how mitochondrial networks are altered by genetic changes in the Optineurin gene. …”
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The dual GGDEF/EAL domain enzyme PA0285 is a Pseudomonas species housekeeping phosphodiesterase regulating early attachment and biofilm architecture by Eilers, Kira, Yam, Joey Kuok Hoong, Liu, Xianghui, Goh, Yu Fen, To, Ka-Ning, Paracuellos, Patricia, Morton, Richard, Brizuela, Jaime, Yong, Adeline Mei Hui, Givskov, Michael, Freibert, Sven-Andreas, Bange, Gert, Rice, Scott A., Steinchen, Wieland, Filloux, Alain

“…Here, we confirm that its role is conserved in various P. aeruginosa strains and in Pseudomonas putida. …”
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Layer-by-layer assembled micro and nano carriers for drug delivery applications by Mutukumaraswamy Shaillender

“…Up regulation of cysteine proteases in tumor cells constitute a major role in extra cellular matrix (ECM) degradation and metastatic invasion. …”
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Electro spun dual structured and three-dimensional biodegradable scaffolds for bone and cartilage tissue engineering by Vidya Chamundeswari Narasimhan

“…Tissue engineering (TE) is envisaged to play a vital role in improving the quality of life by restoring, maintaining or enhancing tissue and organ functions. …”
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Detection of single-nucleotide polymorphisms in Plasmodium falciparum by PCR primer extension and lateral flow immunoassay by Moers, APHA, Hallett, R, Burrow, R, Schallig, HDFH, Sutherland, CJ, van Amerongen, A

“…Primer extension methods (PEXT) were developed to identify 4 SNPs in P. falciparum positioned at amino acids 86, 184, and 1246 of the P. falciparum multidrug resistance 1 gene (pfmdr1) and amino acid 76 of the chloroquine resistance transporter gene (pfcrt). …”