Antigen presentation dynamics shape the antibody response to variants like SARS-CoV-2 Omicron after multiple vaccinations with the original strain by Yang, Leerang, Van Beek, Matthew, Wang, Zijun, Muecksch, Frauke, Canis, Marie, Hatziioannou, Theodora, Bieniasz, Paul D, Nussenzweig, Michel C, Chakraborty, Arup K

“…The Omicron variant of SARS-CoV-2 is not effectively neutralized by most antibodies elicited by two doses of mRNA vaccines, but a third dose increases anti-Omicron neutralizing antibodies. …”
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Dynamics of SARS-CoV-2 infection over two epidemic waves in Manaus, Brazil: A serological study of seven thousand blood donors by Alexander, N, Dye, C, Busch, MP, Buss, L, Prete, CA, Brady, OJ, Mee, P, Abrahim, CMM, Crispim, MAE, da Costa, AG, Salomon, T, Mayaud, P, Oikawa, MK, Faria, NR, Sabino, EC

“…Seroconversion was inferred by a mixture model for serial values from the Abbott Architect SARS-CoV-2 nucleocapsid (N) IgG assay. We estimated the number of suspected COVID-19 hospitalizations arising from each infection over calendar time. …”

The cellular characterization of SARS-CoV-2 spike protein in virus-infected cells using the receptor binding domain binding specific human monoclonal antibodies by Chan, Conrad En-Zuo, Ng, Ching-Ging, Lim, Angeline Pei-Chew, Seah, Shirley Lay-Kheng, Chye, De-Hoe, Wong, Steven Ka-Khuen, Lim, Jie-Hui, Lim, Vanessa Zi-Yun, Lai, Soak-Kuan, Wong, Pui-San, Leong, Kok-Mun, Liu, Yi-Chun, Sugrue, Richard J., Tan, Boon Huan

“…A human monoclonal antibody panel (PD4, PD5, PD7, SC23, and SC29) was isolated from the B cells of convalescent patients and used to examine the S protein in SARS-CoV-2-infected cells. While all five antibodies bound conformational-specific epitopes within SARS-CoV-2 spike (S) protein, only PD5, PD7, and SC23 were able to bind to the receptor binding domain (RBD). …”
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Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2 by Gu, Yue, Shunmuganathan, Bhuvaneshwari, Qian, Xinlei, Gupta, Rashi, Tan, Rebecca S. W., Kozma, Mary, Purushotorman, Kiren, Murali, Tanusya M., Tan, Nikki Y. J., Preiser, Peter Rainer, Lescar, Julien, Nasir, Haziq, Somani, Jyoti, Tambyah, Paul A., Smith, Kenneth G. C., Renia, Laurent, Ng, Lisa F. P., Lye, David C., Young, Barnaby E., MacAry, Paul A.

“…The scale and duration of neutralizing antibody responses targeting SARS-CoV-2 viral variants represents a critically important serological parameter that predicts protective immunity for COVID-19. …”
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Clinical course, immunogenicity, and efficacy of BNT162b2 mRNA vaccination against SARS-CoV-2 infection in liver transplant recipients by Tan, Eunice X., Lim, Wen Hui, Thong, Elizabeth, Chavatte, Jean-Marc, Zhang, Jinyan, Lim, Jonathan, Jin, Jocelyn Y., Lim, Daniel R. X., Kang, Jaclyn Y. T., Tang, Ansel Shao Pin, Chan, Kai En, Tan, Caitlyn, Tan, Shi Ni, Nah, Benjamin, Huang, Daniel Q., Wang, Lin-Fa, Tambyah, Paul A., Somani, Jyoti, Young, Barnaby Edward, Muthiah, Mark D.

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Urban flood detection with Sentinel-1 Multi-Temporal Synthetic Aperture Radar (SAR) observations in a Bayesian Framework : a case study for Hurricane Matthew by Lin, Nina Yunung, Yun, Sang-Ho, Bhardwaj, Alok, Hill, Emma M.

Subjects: “…SAR Intensity Time Series…”
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Socioeconomic inequalities in risk of infection with SARS-CoV-2 delta and omicron variants in the UK, 2020-22: analysis of the longitudinal COVID-19 Infection Survey by Razieh, C, Shabnam, S, Dambha-Miller, H, Morris, EJA, Yates, T, Chudasama, Y, Zaccardi, F, Gillies, C, Banerjee, A, Pareek, M, Lacey, B, White, M, Khunti, K, Islam, N

“…<p><strong>Objective</strong> To explore the risk of a positive test result for the delta or omicron variant of the SARS-CoV-2 virus in different occupations and deprivation groups in the UK.…”

Effectiveness and user experience of nose and throat swabbing techniques for SARS-CoV-2 detection: results from the UK COVID-19 National Testing Programme by Futschik, ME, Kulasegaran-Shylini, R, Blandford, E, Harper, S, Chapman, D, Turek, E, Agrawal, S, Phillips, V, Fordham, H, Chan, L, Kidd, M, Dodgson, A, Klapper, PE, Sudhanva, M, Vipond, R, Hopkins, S, Peto, T, Tunkel, S, Fowler, T

“…Background: The UK’s National Health Service Test and Trace (NHSTT) program aimed to provide the most effective and accessible SARS-CoV-2 testing approach possible. Early user feedback indicated that there were accessibility issues associated with throat swabbing. …”

Imprinting of IgA responses in previously infected individuals receiving bivalent mRNA vaccines (WT and BA.4/BA.5 or WT and BA.1) by Goh, Yun Shan, Fong, Siew-Wai, Hor, Pei Xiang, Loh, Chiew Yee, Tay, Matthew Zirui, Wang, Bei, Salleh, Siti Nazihah Mohd, Ngoh, Eve Zi Xian, Lee, Raphael Tze Chuen, Poh, Xuan Ying, Lee, I. Russel, Rao, Suma, Chia, Po Ying, Maurer-Stroh, Sebastian, Wang, Cheng-I, Leo, Yee Sin, Lye, David C., Young, Barnaby Edward, Ng, Lisa F. P., Renia, Laurent

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Virus-like particles of nodavirus displaying the receptor binding domain of SARS-CoV-2 spike protein: a potential VLP-based COVID-19 vaccine by Kumar, Kiven, Tan, Wen Siang, Arshad, Siti Suri, Ho, Kok Lian

“…The efficacy of the initial vaccines based on the ancestral strain of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) has become a point of contention due to the emergence of new variants of concern (VOCs). …”
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MECHANICS OF MATERIALS by Ferdinand P. Beer, E. Russell Johnston, Jr., John T. Dewolf

Event rates and incidence of post-COVID-19 condition in hospitalised SARS-CoV-2 positive children and young people and controls across different pandemic waves: exposure-stratified prospective cohort study in Moscow (StopCOVID) by Pazukhina, E, Rumyantsev, M, Baimukhambetova, D, Bondarenko, E, Markina, N, El-Taravi, Y, Petrova, P, Ezhova, A, Andreeva, M, Iakovleva, E, Bobkova, P, Pikuza, M, Trefilova, A, Abdeeva, E, Galiautdinova, A, Filippova, Y, Bairashevskaia, A, Zolotarev, A, Bulanov, N, DunnGalvin, A, Chernyavskaya, A, Kondrikova, E, Kolotilina, A, Gadetskaya, S

“…This study aimed to investigate the incidence of post-COVID-19 condition (PCC) and incomplete recovery in CYP after hospital discharge and compare outcomes between different SARS-CoV-2 variants and non-SARS-CoV-2 infections.…”

Ground moving target imaging by synthetic aperture radar based on an unified framework of keystone transformation by Yang, Lei, Zhao, Lifan, Wang, Lu, Bi, Guoan

Subjects: “…Synthetic aperture radar (SAR)…”
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Behaviorally informed digital campaigns and their association with social media engagement and COVID-19 vaccine uptake in Belize by Daga, Giuliana, Kossuth, Lajos, Boruchowicz, Cynthia, Lopez Boo, Florencia, Largaespada Beer, Natalia

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Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in Kenya by Lugano, D, Kutima, B, Kimani, M, Sigilai, A, Gitonga, J, Karani, A, Akech, D, Karia, B, Ziraba, AK, Maina, A, Lambisia, A, Omuoyo, D, Mugo, D, Lucinde, R, Owuor, S, Konyino, G, Newman, J, Bailey, D, Nduati, E, Githinji, G, Agoti, CN, Bejon, P, Scott, JAG, Agweyu, A, Warimwe, GM

“…Increased immune evasion by emerging and highly mutated SARS-CoV-2 variants is a key challenge to the control of COVID-19. …”

Summative and formative style anatomy practical examinations: do they have impact on students' performance and drive for learning? by Mogali, Sreenivasulu Reddy, Rotgans, Jerome Ingmar, Rosby, Lucy, Ferenczi, Michael Alan, Beer, Naomi Low

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Inducing System-1-type diagnostic reasoning in second-year medical students within 15 minutes by Rosby, Lucy Victoria, Rotgans, Jerome Ingmar, Tan, Gerald, Low-Beer, Naomi, Mamede, Silvia, Zwaan, Laura, Schmidt, Henk

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Vaccines: The Health of Nations - A Paradigm Shift by Datta, Shoumen

Subjects: “…Plants, Arabidopsis, Viral Antigens, Viral Vectors, Transgenic Plants, Vaccination, Immunization, SARS-CoV-2, Ebola, Marburg, Noro Virus, Molecular Virology, Golden Rice, Peter Beyer, Ingo Potrykus…”
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Digital problem-based learning in health professions : systematic review and meta-analysis by the digital health education collaboration by Car, Lorainne Tudor, Kyaw, Bhone Myint, Dunleavy, Gerard, Smart, Neil A., Semwal, Monika, Rotgans, Jerome Ingmar, Low-Beer, Naomi, Campbell, James

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Pilot feasibility study to determine the utility of direct access and quantitative magnetic resonance cholangiopancreatography (MRCP) in the assessment of suspected acute biliary o... by Novak, A, Acharya, A, Beer, S, Espinosa, A, Smith, GB, Saga, C, Andrews, J, Bailey, A, Soonawalla, Z, Bungay, H, Pavlides, M