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The oil sorption behaviour investigation of Kapok (Ceiba pentandra (L.)) fiber
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Structural features distinguishing infectious ex vivo mammalian prions from non-infectious fibrillar assemblies generated in vitro
Published 2019“…Seeded polymerisation of proteins forming amyloid fibres and their spread in tissues has been implicated in the pathogenesis of multiple neurodegenerative diseases: so called "prion-like" mechanisms. While ex vivo mammalian prions, composed of multichain assemblies of misfolded host-encoded prion protein (PrP), act as lethal infectious agents, PrP amyloid fibrils produced in vitro generally do not. …”
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Ex vivomammalian prions are formed of paired double helical prion protein fibrils
Published 2016“…Recently, we developed novel methods to obtain exceptionally pure preparations of prions from mouse brain and showed that pathogenic PrP in these high-titre preparations is assembled into rod-like assemblies. Here, we have used precise cell culture-based prion infectivity assays to define the physical relationship between the PrP rods and prion infectivity and have used electron tomography to define their architecture. …”
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Prion 2016 poster abstracts
Published 2016“…We have recently developed novel methods to obtain exceptionally pure preparations of prions from prion-infected murine brain and have shown that pathogenic PrP in these high-titer preparations is assembled into rod-like assemblies (Wenborn et al. 2015. Sci. Rep. 10062). …”
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Highly infectious prions are not directly neurotoxic
Published 2020“…While it has long been assumed that prions are themselves neurotoxic, recent devel- opment of methods to obtain exceptionally pure prions from mouse brain with maintained strain characteristics, and in which defined structures—paired rod-like double helical fibers—can be definitively correlated with infectivity, allowed a direct test of this assertion. …”
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An improved artificial bee colony algorithm for training multilayer perceptron in time series prediction
Published 2014“…Learning an Artificial Neural Network (ANN) is an optimization task since it is desirable to find optimal weight sets of an ANN in the training process. …”
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Statistical process control in stamping process using pattern recognition approach
Published 2018“…Recently, there are still debates amongst researchers to find an effective technique for online monitoring and diagnosing UPV sources. …”
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Introducing an electronic portfolio : results of a one-semester pilot
Published 2009“…As part of this scheme, every undergraduate course includes a core spine module at each level: HEO (Higher Education Orientation) - a subject specific introduction to HE study module in the first year, an employability related module at level 2, and a project in the final year. …”
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Minute book of the Council of Irish County Association, 1966-1967
Published 1966“…Grey marbled paper covers, blue cloth spine. Manuscript.…”
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Minutes -
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Minute book of the Council of Irish County Association, 1963-1969
Published 1963“…Brown covers, light brown cloth spine. Manuscript, with typescript insertions.…”
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Minutes -
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Administrative Committee Minute Book. 1976-1982
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Biomedical Analysis of Lateral Lumbar Interbody Fusion (LLIF) Cage for Lumbar Vertebrae
Published 2023“…Conclusion: Choosing a mechanically compatible interbody cage design is crucial for achieving biomechanical success in spine surgery…”
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