Showing 141 - 160 results of 3,014 for search '(((shi OR (spine OR (ann OR adam))) OR (like OR find)) OR (spink OR eng))', query time: 0.08s Refine Results
  1. 141
  2. 142

    Structural features distinguishing infectious ex vivo mammalian prions from non-infectious fibrillar assemblies generated in vitro by Terry, Cassandra, Harniman, Robert L., Sells, Jessica, Wenborn, Adam, Joiner, Susan, Saibil, Helen R., Miles, Mervyn J., Collinge, John, Wadsworth, Jonathan D. F.

    Published 2019
    “…Seeded polymerisation of proteins forming amyloid fibres and their spread in tissues has been implicated in the pathogenesis of multiple neurodegenerative diseases: so called "prion-like" mechanisms. While ex vivo mammalian prions, composed of multichain assemblies of misfolded host-encoded prion protein (PrP), act as lethal infectious agents, PrP amyloid fibrils produced in vitro generally do not. …”
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    Article
  3. 143
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  8. 148

    Ex vivomammalian prions are formed of paired double helical prion protein fibrils by Terry, Cassandra, Wenborn, Adam, Gros, Nathalie, Sells, Jessica, Joiner, Susan, Hosszu, Laszlo L. P., Tattum, M. Howard, Panico, Silvia, Clare, Daniel K., Collinge, John, Saibil, Helen R., Wadsworth, Jonathan D. F.

    Published 2016
    “…Recently, we developed novel methods to obtain exceptionally pure preparations of prions from mouse brain and showed that pathogenic PrP in these high-titre preparations is assembled into rod-like assemblies. Here, we have used precise cell culture-based prion infectivity assays to define the physical relationship between the PrP rods and prion infectivity and have used electron tomography to define their architecture. …”
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    Article
  9. 149

    Prion 2016 poster abstracts by Terry, Cassandra, Wenborn, Adam, Gros, Nathalie, Sells, Jessica, Joiner, Susan, Hosszu, Laszlo L. P., Tattum, M. Howard, Panico, Silvia, Clare, Daniel K., Collinge, John, Saibil, Helen R., Wadsworth, Jonathan D. F.

    Published 2016
    “…We have recently developed novel methods to obtain exceptionally pure preparations of prions from prion-infected murine brain and have shown that pathogenic PrP in these high-titer preparations is assembled into rod-like assemblies (Wenborn et al. 2015. Sci. Rep. 10062). …”
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  10. 150
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  12. 152

    Highly infectious prions are not directly neurotoxic by Benilova, Iryna, Reilly, Madeleine, Terry, Cassandra, Wenborn, Adam, Schmidt, Christian, Marinho, Aline T., Risse, Emmanuel, Al-Doujaily, Huda, Wiggins De Oliveira, Michael, Sandberga, Malin K., Wadsworth, Jonathan D. F., Jat, Parmjit S, Collinge, John

    Published 2020
    “…While it has long been assumed that prions are themselves neurotoxic, recent devel- opment of methods to obtain exceptionally pure prions from mouse brain with maintained strain characteristics, and in which defined structures—paired rod-like double helical fibers—can be definitively correlated with infectivity, allowed a direct test of this assertion. …”
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  13. 153
  14. 154

    An improved artificial bee colony algorithm for training multilayer perceptron in time series prediction by Shah, Habib

    Published 2014
    “…Learning an Artificial Neural Network (ANN) is an optimization task since it is desirable to find optimal weight sets of an ANN in the training process. …”
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    Thesis
  15. 155

    Statistical process control in stamping process using pattern recognition approach by Abdul Rahman, Norasulaini

    Published 2018
    “…Recently, there are still debates amongst researchers to find an effective technique for online monitoring and diagnosing UPV sources. …”
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    Thesis
  16. 156

    Introducing an electronic portfolio : results of a one-semester pilot by Chalk, Peter

    Published 2009
    “…As part of this scheme, every undergraduate course includes a core spine module at each level: HEO (Higher Education Orientation) - a subject specific introduction to HE study module in the first year, an employability related module at level 2, and a project in the final year. …”
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  17. 157

    Minute book of the Council of Irish County Association, 1966-1967 by Irish County Association, ICA

    Published 1966
    “…Grey marbled paper covers, blue cloth spine. Manuscript.…”
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    Minutes
  18. 158

    Minute book of the Council of Irish County Association, 1963-1969 by Irish County Association, ICA

    Published 1963
    “…Brown covers, light brown cloth spine. Manuscript, with typescript insertions.…”
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    Minutes
  19. 159

    Administrative Committee Minute Book. 1976-1982 by London Irish Centre, LIC

    “…Blue cloth covers with red spine and corners.…”
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    Minutes
  20. 160

    Biomedical Analysis of Lateral Lumbar Interbody Fusion (LLIF) Cage for Lumbar Vertebrae by Zulkefli, Aiman Asiqin, Mazlan, Muhammad Hazli, Takano, Hiromitsu, Md Salleh, Nur Saliha, Jalil, Muhammad Hilmi

    Published 2023
    “…Conclusion: Choosing a mechanically compatible interbody cage design is crucial for achieving biomechanical success in spine surgery…”
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    Article