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  1. 2461

    PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism by Salvadó, Laia, Barroso, Emma, Gómez-Foix, Anna Maria, Palomer, Xavier, Michalik, Liliane, Wahli, Walter, Vázquez-Carrera, Manuel

    Published 2014
    “…Methods Studies were conducted in mouse C2C12 myotubes, in the human myogenic cell line LHCN-M2 and in skeletal muscle from wild-type and PPARβ/δ-deficient mice and mice exposed to a high-fat diet. …”
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    Journal Article
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  5. 2465

    PPARβ/δ agonism upregulates forkhead box A2 to reduce inflammation in C2C12 myoblasts and in skeletal muscle by Phua, Wendy Wen Ting, Tan, Wei Ren, Yip, Yun Sheng, Hew, Ivan Dongzheng, Wee, Jonathan Wei Kiat, Cheng, Hong Sheng, Leow, Melvin Khee Shing, Wahli, Walter, Tan, Nguan Soon

    Published 2020
    “…This reduced local inflammatory response limits tissue damage and restores muscle tetanic contraction. In line with these results, a deficiency in either PPARβ/δ or FoxA2 diminishes the action of the PPARβ/δ agonist GW501516 to suppress an aggravated inflammatory response. …”
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    Journal Article
  6. 2466
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    Structural integrity assessment of rail steel failure modes and mechanism by Liu, Yang

    Published 2021
    “…Transverse weld-toe surface cracks at the fusion line of the welded joint are found to be caused by the high density of weld defects and the mismatch of strength and fatigue properties between the thermite weld metal and unaffected rail steel. …”
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    Thesis-Doctor of Philosophy
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  14. 2474

    Towards in-situ texture analysis during LPBF: optical microscopy and texture control by Wang, Xiaogang

    Published 2023
    “…Finally, I present my attempts atix enabling optical microstructural analysis, in-line, during L-PBF processes (Chapter 4). To this end, I integrated special surface processing techniques as well as the optical characterization methods described in the previous chapters inside a custom-made L-PBF system. …”
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    Thesis-Doctor of Philosophy
  15. 2475

    Viral proteases activate the CARD8 inflammasome in the human cardiovascular system by Nadkarni, Rhea, Chu, Wern Cui, Lee, Cheryl Q. E., Mohamud, Yasir, Yap, Lynn, Toh, Gee Ann, Beh, Sheryl, Lim, Radiance, Fan, Michelle Yiyun, Zhang, Lyanne Yizhuo, Robinson, Kim, Tryggvason, Karl, Luo, Honglin, Zhong, Franklin, Ho, Lena

    Published 2023
    “…The endothelium is the first line of defense against blood-borne pathogens, but it is unclear which NLRs control endothelial cell (EC) intrinsic immunity. …”
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    Journal Article
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