AI is a viable alternative to high throughput screening: a 318-target study by Wallach, Izhar, Bernard, Denzil, Nguyen, Kong, Ho, Gregory, Morrison, Adrian, Stecula, Adrian, Rosnik, Andreana, O’Sullivan, Ann Marie, Davtyan, Aram, Samudio, Ben, Thomas, Bill, Worley, Brad, Butler, Brittany, Laggner, Christian, Thayer, Desiree, Moharreri, Ehsan, Friedland, Greg, Truong, Ha, van den Bedem, Henry, Ng, Ho Leung, Stafford, Kate, Sarangapani, Krishna, Giesler, Kyle, Ngo, Lien, Mysinger, Michael, Ahmed, Mostafa, Anthis, Nicholas J., Henriksen, Niel, Gniewek, Pawel, Eckert, Sam, de Oliveira, Saulo, Suterwala, Shabbir, PrasadPrasad, Srimukh Veccham Krishna, Shek, Stefani, Contreras, Stephanie, Hare, Stephanie, Palazzo, Teresa, O’Brien, Terrence E., Van Grack, Tessa, Williams, Tiffany, Chern, Ting-Rong, Kenyon, Victor, Lee, Andreia H., Cann, Andrew B., Bergman, Bastiaan, Anderson, Brandon M., Cox, Bryan D., Warrington, Jeffrey M., Sorenson, Jon M., Goldenberg, Joshua M., Young, Matthew A., DeHaan, Nicholas, Pemberton, Ryan P., Schroedl, Stefan, Abramyan, Tigran M., Gupta, Tushita, Mysore, Venkatesh, Presser, Adam G., Ferrando, Adolfo A., Andricopulo, Adriano D., Ghosh, Agnidipta, Ayachi, Aicha Gharbi, Mushtaq, Aisha, Shaqra, Ala M., Toh, Alan Kie Leong, Smrcka, Alan V., Ciccia, Alberto, de Oliveira, Aldo Sena, Sverzhinsky, Aleksandr, de Sousa, Alessandra Mara, Agoulnik, Alexander I., Kushnir, Alexander, Freiberg, Alexander N., Statsyuk, Alexander V., Gingras, Alexandre R., Degterev, Alexei, Tomilov, Alexey, Vrielink, Alice, Garaeva, Alisa A., Bryant-Friedrich, Amanda, Caflisch, Amedeo, Patel, Amit K., Rangarajan, Amith Vikram, Matheeussen, An, Battistoni, Andrea, Caporali, Andrea, Chini, Andrea, Ilari, Andrea, Mattevi, Andrea, Foote, Andrea Talbot, Trabocchi, Andrea, Stahl, Andreas, Herr, Andrew B., Berti, Andrew, Freywald, Andrew, Reidenbach, Andrew G., Lam, Andrew, Cuddihy, Andrew R., White, Andrew, Taglialatela, Angelo

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Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community by Zhang, Chengyu, Sánchez, Benjamín J., Li, Feiran, Cheng, Eiden Wei Quan, Scott, William T., Liebal, Ulf W., Blank, Lars M., Mengers, Hendrik G., Anton, Mihail, Rangel, Albert Tafur, Mendoza, Sebastián N., Zhang, Lixin, Nielsen, Jens, Lu, Hongzhong, Kerkhoven, Eduard J.

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Modeling and optimization of photovoltaic systems under partially shaded and rapidly changing conditions by Jiang, Lian Lian

“…Since the existing methods show either low accuracy in derived parameters of the PV array or too much complexity in their calculation, in Chapter 3, we proposed a Chebyshev functional link neural network (CFLNN) to model the PV module. …”
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Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study by Plewes, Katherine, Kingston, Hugh W.F., Ghose, Aniruddha, Maude, Richard J., Herdman, M. Trent, Leopold, Stije J., Ishioka, Haruhiko, Hasan, Md. Mahtab Uddin, Haider, Md. Shafiul, Alam, Shamsul, Piera, Kim A., Charunwatthana, Prakaykaew, Silamut, Kamolrat, Yeo, Tsin Wen, Faiz, Md. Abul, Lee, Sue J., Mukaka, Mavuto, Turner, Gareth D. H., Anstey, Nicholas M., Jackson Roberts II, L., White, Nicholas J., Day, Nicholas P. J., Hossain, Md. Amir, Dondorp, Arjen M.

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Physiological stress responses and meat quality of rabbits subjected to different road transportation and slaughter methods by Khadijah, Nakyinsige

“…This study describes the link between physiological stress responses to transport and slaughter to meat quality using rabbit as a model. …”
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Effects of nnav1.5 expression modulation on mhc I antigen processing machinery and invasion potential of breast cancer cells by Din, Ahmad Hafiz Murtadha Noor

“…Loss of immune surveillance enables cancer cells to metastasize hence this study is to explore the possible role of nNav1.5 in regulating the expression of immune components, MHC I antigen processing machinery (APM), which is deregulated in breast cancer. Several reports link VGSC and APM in neurons, but the correlation between nNav1.5 and APM in breast cancer is unknown. …”
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Hybrid mesoporous microbeads based on sheets-like sulfur-doped copper oxide embedded in calcium alginate-derived carbon for batch and columnar adsorption of cationic dye by Naggar, Ahmed H., Alshammari, Mutairah S., Seaf-Elnasr, Tarek A., Chong, Kwok Feng, Bakr, Zinab H., Alotaibi, N. F., Ali, Hazim M., El-Nasser, Karam S., Thabet, Mahmoud, Abd El-Monaem, Eman M., Goda, Adel E. S., Gomaa, Hassanien

“…The columnar adsorption tests showed that the adsorption capacity of SCO@CACBs varied from 83.6 to 71.3 mg/g as the flow rate varied from 2 to 6 mL/min and 81.5–115.6 mg/g as the adsorbent mass varied from 1 to 4 g. …”
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Temporal pressure enhanced topical drug delivery through micropore formation by Lio, Daniel Chin Shiuan, Chia, Ruining, Kwek, Milton Sheng Yi, Wiraja, Christian, Madden, Leigh Edward, Chang, Hao, S. Mohideen Abdul Khadir, Wang, Xiaomeng, Becker, David Lawrence, Xu, Chenjie

“…The creation of micropores (~3 μm2) on the epidermal layer through a temporal pressure treatment results in the elevated expression of gap junctions, and reduced expression of occludin tight junctions. A 1 min treatment of 0.28-MPa allows nanoparticles (up to 500 nm) and macromolecules (up to 20 kDa) to reach a depth of 430-μm into the dermal layer. …”
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新加坡福建话马来语及英借词使用情况调查 = Usage of English and Malay loanwords amongst Singapore Hokkien speakers by 张良忆 Teo, Joey Liang Yi

“…Hokkien being the most widely spoken dialect in Singapore, has therefore attracted much attention. Compared to other Min dialects, Hokkien in Singapore consist of a large number of English and Malay loanwords. …”
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Effectiveness of a chronic obstructive pulmonary disease integrated care pathway in a regional health system : a propensity score matched cohort study by Wu, Christine Xia, Hwang, Chi Hong, Tan, Woan Shin, Tai, Kai Pik, Kwek, Lynette Siang Lim, Chee, Thong Gan, Choo, Yee Mun, Phng, Francis Wei Loong, Chua, Gerald Seng Wee

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Ergogenic and metabolites analyses of piyarom date (Phoenix dactylifera L.) using NMR-based metabolomics and its effect on Sprague dawley rats by Shanan, Hana Kadum

“…Results of in vivo study showed that rats treated with 500 mg/kg BW Piyarom date extract demonstrated the longest endurance capacity of 10 min, that is significantly higher than that of caffeine-treated rats, as measured by forced swimming test. …”
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Culture of human pluripotent stem cells and neural networks in 3D using an optogenetic approach and a hydrogel model by Lee, S

“…Investigation of cell response reveals that a flow rate of 3 ml/min and an alginate concentration of 1.8% (w/v) are optimal and that stem cell survival is significantly improved through incorporation of RGD and ROCKi. …”

Efficient storage codes for non-volatile memories by Chua, Melissa Wan Jun

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The prospective associations of 24-hour movement behaviors and domain-specific activities with executive function and academic achievement among school-aged children in Singapore by Padmapriya, Natarajan, Bernard, Jonathan Y., Tan, Sarah Yi Xuan, Chu, Anne H. Y., Goh, Claire Marie Jie Lin, Tan, Shuen Lin, Shek, Lynette P., Chong, Yap Seng, Tan, Kok Hian, Chan, Shiao-Yng, Yap, Fabian, Godfrey, Keith M., Lee, Yung Seng, Meaney, Michael J., Eriksson, Johan G., Tan, Chuen Seng, Law, Evelyn C., Müller-Riemenschneider, Falk

“…Background: Physical activity (PA), sedentary behavior (SB), and sleep are collectively referred to as 24-h movement behaviors, which may be linked to cognitive development in children. However, most of the evidence was based on cross-sectional studies and/or solely relied on parent-reported information on children’s behaviors, and it remains uncertain whether all domains/contexts of PA and SB are similarly associated with executive function and academic achievement. …”
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The IDentif.AI-x pandemic readiness platform: rapid prioritization of optimized COVID-19 combination therapy regimens by Blasiak, Agata, Truong, Anh T. L., Remus, Alexandria, Hooi, Lissa, Seah, Shirley Gek Kheng, Wang, Peter, Chye, De Hoe, Lim, Angeline Pei Chiew, Ng, Kim Tien, Teo, Swee Teng, Tan, Yee-Joo, Allen, David Michael, Chai, Louis Yi Ann, Chng, Wee Joo, Lin, Raymond T. P., Lye, David C., Wong, John Eu-Li, Tan, Gladys Gek-Yen, Chan, Conrad En Zuo, Chow, Edward Kai-Hua, Ho, Dean

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Scope, characteristics, behavior change techniques, and quality of conversational agents for mental health and well-being: systematic assessment of apps by Lin, Xiaowen, Martinengo, Laura, Jabir, Ahmad Ishqi, Ho, Andy Hau Yan, Car, Josip, Atun, Rifat, Tudor Car, Lorainne

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Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2 by Gu, Yue, Shunmuganathan, Bhuvaneshwari, Qian, Xinlei, Gupta, Rashi, Tan, Rebecca S. W., Kozma, Mary, Purushotorman, Kiren, Murali, Tanusya M., Tan, Nikki Y. J., Preiser, Peter Rainer, Lescar, Julien, Nasir, Haziq, Somani, Jyoti, Tambyah, Paul A., Smith, Kenneth G. C., Renia, Laurent, Ng, Lisa F. P., Lye, David C., Young, Barnaby E., MacAry, Paul A.

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Ultrastrong exciton-plasmon couplings in WS2 multilayers synthesized with a random multi-singular metasurface at room temperature by Wu, Tingting, Wang, Chongwu, Hu, Guangwei, Wang, Zhixun, Zhao, Jiaxin, Wang, Zhe, Chaykun, Ksenia, Liu, Lin, Chen, Mengxiao, Li, Dong, Zhu, Song, Xiong, Qihua, Shen, Zexiang, Gao, Huajian, Garcia-Vidal, Francisco J., Wei, Lei, Wang, Qi Jie, Luo, Yu

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Electrospun carbon-silica composite nanofibers for selective removal of oil and water by Tai, Ming Hang

“…After surface-coating with silicone oil for 30 min, the composite membrane exhibited ultra-hydrophobic and superoleophilic properties with water and oil contact angles being 144.2 ± 1.2° and 0°, respectively. …”
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Establishment of optimise strategies in production of recombinant Hepatitis B surface antigen for chip-based antibody detection approach by Tam, Yew Joon

“…The main results drawn showed that the IEC Q Sepharose XL column and optimum conditions of 4 mL sample loading volume, an elution buffer with 1.5 M NaCl concentration at pH 8 with an elution gradient length of 20 column volume and subsequent purification with SEC at a sample volume of 5 mL and a flow rate of 1 mL/min was able to efficiently purify HBsAg. An up-scaled version the established purification strategy comprising of the two techniques further demonstrated adaptability for scale-up operations with a final total PF of 94.82 ± 16.20, HBsAg purity of 95.48% and recovery yield of 78.07%. …”
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