Evolutionary explanations and the debunking of moral beliefs by Cofnas, N

“…I argue that our innate moral faculty is likely not the product of natural selection, but rather social selection. …”

Magnetoresistive sensor development roadmap (non-recording applications) by Zheng, Chao, Zhu, Ke, De Freitas, Susana Cardoso, Chang, Jen-Yuan, Davies, Joseph E., Eames, Peter, Freitas, Paulo P., Kazakova, Olga, Kim, Cheol Gi, Leung, Chi-Wah, Liou, Sy-Hwang, Ognev, Alexey, Piramanayagam, S. N., Ripka, Pavel, Samardak, Alexander, Shin, Kwang-Ho, Tong, Shi-Yuan, Tung, Mean-Jue, Wang, Shan X., Xue, Songsheng, Yin, Xiaolu, Pong, Philip W. T.

“…This paper provides a framework for MR sensor technology (non-recording applications) to be used for public and private R&D planning, in order to provide guidance into likely MR sensor applications, products, and services expected in the next 15 years and beyond.…”
Get full text

Vulnerability modeling, assessment, and improvement in urban metro systems: a probabilistic system dynamics approach by Chen, Hongyu, Chen, Bin, Zhang, Limao, Li, Hong Xian

“…The urban metro system is a complex system that is vulnerable to various kinds of hazards and subjected to dynamics, where errors in any part are very likely to cause system failures and accidents. A better understanding of evolutional dynamics of the system vulnerability over time enables to ensure the safety and security in its operation and provide guidance for long-term operation and maintenance for the metro system. …”
Get full text

Data-driven approach to spatiotemporal dynamic risk assessment of urban flooding based on shared socio-economic pathways by Wang, Mo, Chen, Furong, Zhang, Dongqing, Chen, Zijing, Su, Jin, Zhou, Shiqi, Li, Jianjun, Chen, Jintang, Li, Jiaying, Tan, Soon Keat

“…Under SSP126 scenario, nearly no change was predicted in the area with high flooding risk, with only increase of 1%, future urbanization hotspots associated with serious flooding risks will likely to be found on the fringe of the GBA's construction areas, in line with the extent of construction land expansion. …”
Get full text

Estimating building vulnerability to volcanic ash fall for insurance and other purposes by Jenkins, Susanna F., Magill, C. R., Wilson, T. M., McMullan, K., Kandlbauer, J., Blong, R. J., Grasso, P.

“…Ash fall vulnerability curves or functions, which relate the magnitude of ash fall to likely damage, are the most developed for buildings, although there have been important recent advances for agriculture and infrastructure. …”
Get full text
Get full text

Characterization and gene expression analysis of the cir multi-gene family of plasmodium chabaudi chabaudi (AS) by Lawton, Jennifer, Brugat, Thibaut, Yan, Yam Xue, Reid, Adam James, Böhme, Ulrike, Otto, Thomas Dan, Pain, Arnab, Jackson, Andrew, Berriman, Matthew, Cunningham, Deirdre, Preiser, Peter Rainer, Langhorne, Jean

“…Conclusions: In conclusion, the large number of cir genes and their expression throughout the intraerythrocytic cycle of development indicates that CIR proteins are likely to be important for parasite survival. In particular, the detection of dominant cir transcripts at the peak of P. chabaudi infection supports the idea that CIR proteins are expressed, and could perform important functions in the biology of this parasite. …”
Get full text
Get full text

Greater rate of weight loss predicts paediatric hospital admission in adolescent typical and atypical anorexia nervosa by Brennan, Cliona, Cini, Erica, Illingworth, Sarah, Chapman, Simon, Simic, Mima, Nicholls, Dasha, Chapman, Victoria, Simms, Conor, Hayes, Ellen, Fuller, Sarah, Orpwood, Jade, Tweedy, Nichola, Baksh, Tahmida, Astaire, Emma, Bhakta, Dee

“…Underweight adolescents with AN were equally likely to be admitted as non-underweight adolescents with AAN. …”
Get full text

Molecular characterization of microbial interactions with labile dissolved organic matter by Halloran, Kathryn H.

“…This substrate selectivity is likely driven by transporter specificity. The distinct fate of these structurally similar molecules emphasizes the importance of compound-specific characterization of labile DOM. …”
Get full text

Application of in vitro erythropoiesis from bone marrow derived progenitors to detect and study genotoxicity by Shuga, Joseph F. (Joseph Francis)

Get full text

Poisson discretizations of Wiener functionals and Malliavin operators with Wasserstein estimates by Privault, Nicolas, Yam, Phillip S. C., Zhang, Zheng

Get full text

A bilayer swellable drug-eluting stent for the treatment of fibrosis-induced ureteral stricture recurrence by Lim, Wei Shan

“…These observations were likely due to the high equilibrium water content hence promoting the drug release. …”
Get full text

Strategies to increase response rate and reduce non-response bias in population health research: a series of randomised controlled trials during a large COVID-19 study by Atchison, CJ, Gilby, N, Pantelidou, G, Clemens, S, Pickering, K, Chadeau-Hyam, M, Ashby, D, Barclay, WS, Cooke, G, Darzi, A, Riley, S, Donnelly, C, Ward, H, Elliott, P

“…Those receiving an additional text message were more likely to return a completed swab compared to those receiving the standard approach, 73.3% v 70.2%: percentage difference 3.1% (95% CI 2.2%, 4.0%).…”

Immune Checkpoint Blockade sensitivity and Progression-Free Survival associates with baseline CD8+ T cell clone size and cytotoxicity by Watson, R, Tong, O, Taylor, C, Kumar Sharma, P, Verge De Los Aires, A, Mahe, E, Ruffieux, H, Nassiri, I, Middleton, M, Fairfax, B

“…Cytotoxic effector clones were more likely to persist long-term following ICB and overlapped with public tumour-infiltrating lymphocyte clonotypes. …”

Adverse health events associated with antipsychotic use: an umbrella review by Chow, RTS

“…In terms of patient variables, older adults aged over 65 and patients with dementia were more likely to experience antipsychotic-associated adverse outcomes than adults and patients with schizophrenia. …”

Differences in the effectiveness of individual-level smoking cessation interventions by socioeconomic status by Theodoulou, A, Fanshawe, TR, Leavens, E, Theodoulou, E, Wu, AD, Heath, L, Stewart, C, Nollen, N, Ahluwalia, JS, Butler, AR, Hajizadeh, A, Thomas, J, Lindson, N, Hartmann-Boyce, J

“…<p><b>Background</b></p> People from lower socioeconomic groups are more likely to smoke and less likely to succeed in achieving abstinence, making tobacco smoking a leading driver of health inequalities. …”

Early Immune Regulatory Changes in a Primary Controlled Human Plasmodium vivax Infection: CD1c + Myeloid Dendritic Cell Maturation Arrest,... by Yeo, Tsin Wen, Woodberry, Tonia, Loughland, Jessica R., Minigo, Gabriela, Burel, Julie G., Amante, Fiona H., Piera, Kim A., McNeil, Yvette, Good, Michael F., Doolan, Denise L., Engwerda, Christian R., McCarthy, James S., Anstey, Nicholas M.

“…Induction of the kynurenine pathway and increased Treg activation, together with skewed mDC maturation, suggest P. vivax promotes an immunosuppressive environment, likely impairing the development of a protective host immune response.…”
Get full text
Get full text

The effect of the amyloid-beta peptide on the fluidity of cell membranes : a study by fluorescence correlation spectroscopy by Ng, Justin Wei Qing

“…Although there have been several studies done regarding this topic, the results have been conflicting and thus inconclusive, likely due to the drawbacks and biases introduced by techniques used in those studies. …”
Get full text

Selective lighting up of epiberberine alkaloid fluorescence by fluorophore-switching aptamer and stoichiometric targeting of human telomeric DNA G-quadruplex multimer by Zhang, Lihua, Liu, Hua, Shao, Yong, Lin, Clement, Jia, Huan, Chen, Gang, Yang, Danzhou, Wang, Ying

“…The steady-state absorption, steady-state/time-resolved fluorescence, and NMR studies demonstrate that EPI most likely interact with the 5′ end flanking sequence substructure beyond the core [Q] and the G-quadruplex tetrad in a much more specific manner than the other alkaloids. …”
Get full text
Get full text

Structural analysis of the novel influenza A (H7N9) viral Neuraminidase interactions with current approved neuraminidase inhibitors Oseltamivir, Zanamivir, and Peramivir in the pre... by Tran-To Su, Chinh, Ouyang, Xuchang, Zheng, Jie, Kwoh, Chee Keong

“…Results: Combination of molecular docking and Molecular Dynamics simulation reveal that zanamivir forms more favorable and stable complex than oseltamivir and peramivir when binding to the active site of the H7N9 neuraminidase. And it is likely that the novel influenza A (H7N9) virus adopts a higher probability to acquire resistance to peramivir than the other two inhibitors. …”
Get full text
Get full text

Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology by Gould, E, Fraser, HS, Parker, TH, Nakagawa, S, Griffith, SC, Vesk, PA, Fidler, F, Hamilton, DG, Abbey-Lee, RN, Abbott, JK, Aguirre, LA, Alcaraz, C, Aloni, I, Altschul, D, Arekar, K, Atkins, JW, Atkinson, J, Baker, CM, Barrett, M, Bell, K, Bello, SK, Beltrán, I, Berauer, BJ, Bertram, MG, Wood, A

“…In other words, analyses with results that were far from the mean were no more or less likely to have dissimilar variable sets, use random effects in their models, or receive poor peer reviews than those analyses that found results that were close to the mean. …”