Development of immunomodulatory RNA therapeutics for immune disorders by Iyer, Vaishnavi Srinivasan

“…As ASOs have the potential to target any gene, thus greatly expanding the universe of potential drug targets, it represents a viable therapeutic approach to modulate aberrant pathways in diseases like RA. In paper I, we present a present a novel way of using CRISPR-mediated gene knock out to validate the role of target genes in particular cellular pathways of interest. …”
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Dynamic restructuring of Cu-doped SnS2 nanoflowers for highly selective electrochemical CO2 reduction to formate by Chen, Mengxin, Wan, Shipeng, Zhong, Lixiang, Liu, Daobin, Yang, Hongbin, Li, Chengcheng, Huang, Zhiqi, Liu, Chuntai, Chen, Jian, Pan, Hongge, Li, Dong-Sheng, Li, Shuzhou, Yan, Qingyu, Liu, Bin

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Seismic loss dynamics in three Asian megacities using a macro-level approach based on socioeconomic exposure indicators by Sarica, Gizem Mestav, Pan, Tso-Chien

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Dynamic liquid-liquid interface: applying a spinning interfacial microreactor to actively converge biphasic reactants for the enhanced interfacial reaction by Ng, Li Shiuan, Chong, Carice, Lok, Xin Yi, Pereira, Veronica, Ang, Zhi Zhong, Han, Xuemei, Li, Haitao, Lee, Hiang Kwee

“…Herein, we achieve an efficient interfacial reaction by creating a magnetic-responsive, microscale liquid-liquid interface and exploit its dynamic spinning motion to generate vortex-like hydrodynamic flows that rapidly converge biphasic reactants to the point-of-reaction. …”
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Theory-guided machine learning to predict configurational energies of high distortion alloy systems by Huang, Xufa

“…State-of-the-art attempts at using CE with machine learning (ML) models like Lasso and Bayesian for selecting meaningful clusters show high prediction errors for these high distortion alloy systems, where the contributions of long-range effective cluster interactions (ECIs) to configurational energetics remain significant. …”
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IOT integration of a mobile application with a controller-based system: A by Pang, Bryan Seng Keong

“…When asked if they would like new features such as cashless payments and booking systems, to improve the availability and convenience of laundry facilities, a resounding 100% of the residents responded with “strongly agree” [3]. …”
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Valley-optical absorption in planar transition metal dichalcogenide superlattices by Hashemi, R., Shojaei, S., Rezaei, B., Liu, Zheng

“…Within a semi-classical model and using the Dirac-like equation in the presence of light interaction as a perturbation, we obtained the governing Hamiltonian. …”
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Harnessing novel strategies and cell types to overcome immune tolerance during adoptive cell therapy in cancer by Neo, Shi Yong, Xu, Shengli, Chong, Joni, Lam, Kong-Peng, Wu, Jing

“…Finally, we discuss the potential of other innate or innate-like immune cell types currently being explored as promising CAR-cell alternatives that seek to address the limitations of conventional adoptive cell therapies.…”
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Fabrication of organic solvent nanofiltration membranes with graphene oxide - enhanced covalent organic framework via interfacial polymerization by Oor, Jia Zheng, Ong, Chi Siang, Tan, Yong Zen, Chew, Jia Wei

“…Membrane-based filtration offers many benefits like lower energy consumption and operating cost for separation in harsh solvents. …”
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Adder and multiplier design for computing-in-memory architecture based on ReRAM by Zheng, Buyun

“…Compared to processing chips like CPU, memory is too cheap and indispensable in massive computing applications. …”
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3D printing of mycelium engineered living materials using a waste-based ink and non-sterile conditions. by Soh, Eugene, Teoh, Jia Heng, Leong, Brendon, Xing, Tingrong, Le Ferrand, Hortense

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Synthesis, modification and application of fish skin gelatin-based hydrogel as sustainable and versatile bioresource of antidiabetic peptide by Munawaroh, Heli Siti Halimatul, Pratiwi, Riska Nur, Gumilar, Gun Gun, Aisyah, Siti, Rohilah, Siti, Nurjanah, Anisa, Ningrum, Andriati, Susanto, Eko, Pratiwi, Amelinda, Arindita, Ni Putu Yunika, Martha, Larasati, Chew, Kit Wayne, Show, Pau-Loke

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Charge transfer enhancement at the CZTS photocathode interface using ITO for efficient solar water reduction by Tay, Ying Fan, Zhang, Mengyuan, Zhang, Shuo, Lie, Stener, Chiam, Sing Yang, Wong, Lydia Helena

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DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11 by Loh Jia Tong, Teo, Joey Kay Hui, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Andiappan, Anand Kumar, Lim, Hong-Hwa, Lam, Kong-Peng

“…Knocking out Dok3 enhanced the production of the cytokine IFN-γ by T cells, which conferred protection against experimental atopic dermatitis-like skin inflammation in mice. The expression of DOK3 was increased in T cells isolated from patients with atopic dermatitis and inversely correlated with IFNG expression. …”
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Promoting the sustainability of blockchain in web 3.0 and the metaverse through diversified incentive mechanism design by Doe, Daniel Mawunyo, Li, Jing, Dusit, Niyato, Gao, Zhen, Li, Jun, Han, Zhu

“…The success of these technologies is dependent on the utilization of decentralized systems like blockchains, which can store and validate data on identities and reputations and facilitate the exchange of virtual assets. …”
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Deposition and characterisation of a diamond/Ti/diamond multilayer structure by Mallik, Awadesh Kumar, Lloret, Fernando, Gutierrez, Marina, Rouzbahani, Rozita, Pobedinskas, Paulius, Shih, Wen-Ching, Haenen, Ken

“…Ti sputtering on such a CVD-grown diamond surface leads to an imprinted bead-like microstructure of the titanium film, generated from the underlying diamond layer. …”
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Signs of criticality in social explosions by Beiró, Mariano G., Chung, Ning Ning, Chew, Lock Yue, Gandica, Yérali

“…It is natural to think that these kinds of macro social actions, as a consequence of the spontaneous and massive interactions, will attain the growth and divergence of those clusters, like the correlation length of statistical physics, giving rise to important simplifications on several statistics. …”
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Turning the virtual into reality: China's role in the metaverse by Gong, Xue

“…In particular, after Chinese think tanks and regulatory agencies raised alarms regarding national security, the state has taken serious suppressive actions against some metaverse sectors like cryptocurrency.5 China banned all domestic cryptocurrency transactions and mining in 2021. …”
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Analyzing the impact of bicycle geometry and cargo loading on the rideability and safety of cargo bikes: an investigative study by Paudel, Milan, Yap, Fook Fah

“…Results: Long-john cargo bikes are unstable for lightweight cargo loads, more sensitive to cargo loads, and therefore may not be suitable for riding in narrow, crowded spaces like footpaths. Moreover, retrofitted cargo bikes should only be used to carry lightweight cargo as a combination of heavy cargo load and a powerful rear wheel motor poses a potential risk of accidents. …”
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Effects of accelerated carbonation on fine incineration bottom ash: CO2 uptake, strength improvement, densification, and heavy metal immobilization by Sun, Xinlei, Xu, Bo, Yi, Yaolin

“…However, this process generates incineration bottom ash (IBA), which is an aggregate-like waste containing heavy metals. Due to the higher heavy metal contents, fine IBA can be removed from total IBA and treated separately to promote the use of IBA. …”
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