Identification and application of self-binding zipper-like sequences in SARS-CoV spike protein by Zhang, Si Min, Liao, Ying, Neo, Tuan Ling, Lu, Yanning, Liu, Ding Xiang, Vahlne, Anders, Tam, James Pingkwan

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The fine line between jianli guanxi and la guanxi. by Loh, Wan Fong.

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Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer by Alsaiari, Shahad K., Nadeef, Seba, Daristotle, John L., Rothwell, William, Du, Bujie, Garcia, Johnny, Zhang, Linzixuan, Sarmadi, Morteza, Forster, Timothy A., Menon, Nandita, Lin, Stacey Qiaohui, Tostanoski, Lisa H., Hachmann, Nicole, Wang, Erika Yan, Ventura, John D., Barouch, Dan H., Langer, Robert, Jaklenec, Ana

“…In this work, we report the Toll-like receptor agonist activity of a nanoscale adjuvant zeolitic imidazolate framework–8 (ZIF-8). …”
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Virus-like particles of nodavirus displaying the receptor binding domain of SARS-CoV-2 spike protein: a potential VLP-based COVID-19 vaccine by Kumar, Kiven, Tan, Wen Siang, Arshad, Siti Suri, Ho, Kok Lian

“…The receptor binding domain (RBD) of the virus spike (S) glycoprotein has been extensively used in vaccine development due to its role in host cell attachment and penetration. …”
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Intensity of stress singularity for the circumferential V-shape corner front of a three-dimensional diamond-like defect by Ping, X. ., Zhang, Y. X., Guo, Y. B., Xiao, Z. M., Jalde, J., Chen, M. C.

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Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes by Low, Jianrong L., Gehring, Adam J., Kranz, David M., Grotenbreg, Gijsbert M., Yau, Yin Hoe, Shochat, Susana Geifman, Bertoletti, Antonio, Naidoo, Anneta, Yeo, Gladys, Ho, Zi Zong

“…Various protein scaffolds have been designed to recapitulate the specific recognition of presented antigens with the aim to be exploited both diagnostically (e.g. to visualize cells exposed to infectious agents or cellular transformation) and therapeutically (e.g. for the delivery of drugs to compromised cells). In line with this, we report the construction of a soluble tetrameric form of an αβ T cell receptor (TCR) specific for the HBV epitope Env183–191 restricted by HLA-A*02:01, and compare its avidity and fine-specificity with a TCR-like monoclonal antibody generated against the same HLA target. …”
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High-density lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner by Correa, Yubexi, Del Giudice, Rita, Waldie, Sarah, Thépaut, Michel, Micciula, Samantha, Gerelli, Yuri, Moulin, Martine, Delaunay, Clara, Fieschi, Franck, Pichler, Harald, Haertlein, Michael, Forsyth, V. Trevor, Le Brun, Anton, Moir, Michael, Russell, Robert A., Darwish, Tamim, Brinck, Jonas, Wodaje, Tigist, Jansen, Martin, Martín, César, Roosen-Runge, Felix, Cárdenas, Marité

“…It is known that the SARS-CoV-2 spike (S) protein binds the HDL particle, probably depleting it of lipids and altering HDL function. …”
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Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein by Loh, Jia Tong, Teo, Joey Kay Hui, Lam, Kong-Peng

“…However, the precise mechanism controlling calprotectin production during SARS-CoV-2 infection remains elusive. In this study, we showed that Dok3 adaptor restrains calprotectin production by neutrophils in response to SARS-CoV-2 spike (S) protein engagement of TLR4. …”
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Surge in SpikeProp algorithm by Zhang, Zhengyang

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Reactivating and reorganizing activity-silent working memory: two distinct mechanisms underlying pinging the brain by Yang, C, He, X, Cai, Y

“…Recent studies have proposed that visual information in working memory (WM) can be maintained in an activity-silent state and reactivated by task-irrelevant high-contrast visual impulses (“ping”). Although pinging the brain has become a popular tool for exploring activity-silent WM, its underlying mechanisms remain unclear. …”

Biocementation of fine-grained soil by Ong, Jun Hao

“…Further studies are required to understand the mechanisms of the MICP treatment for fine-grained soil.…”
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A spiking neural network for pattern recognition by Nurin Atikah Bohari

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Robustness to training disturbances in SpikeProp Learning by Shrestha, Sumit Bam, Song, Qing

“…Stability is a key issue during spiking neural network training using SpikeProp. The inherent nonlinearity of Spiking Neuron means that the learning manifold changes abruptly; therefore, we need to carefully choose the learning steps at every instance. …”
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The cellular characterization of SARS-CoV-2 spike protein in virus-infected cells using the receptor binding domain binding specific human monoclonal antibodies by Chan, Conrad En-Zuo, Ng, Ching-Ging, Lim, Angeline Pei-Chew, Seah, Shirley Lay-Kheng, Chye, De-Hoe, Wong, Steven Ka-Khuen, Lim, Jie-Hui, Lim, Vanessa Zi-Yun, Lai, Soak-Kuan, Wong, Pui-San, Leong, Kok-Mun, Liu, Yi-Chun, Sugrue, Richard J., Tan, Boon Huan

“…While all five antibodies bound conformational-specific epitopes within SARS-CoV-2 spike (S) protein, only PD5, PD7, and SC23 were able to bind to the receptor binding domain (RBD). …”
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Phenotypic screen of sixty-eight colorectal cancer cell lines identifies CEACAM6 and CEACAM5 as markers of acid-resistance by Michl, J, White, B, Monterisi, S, Bodmer, W, Swietach, P

“…CEACAM5/6 protein levels were strongly induced by acidity, with a further induction under hypoxia in a subset of CRC lines. …”

Frail Line by Er, Kia Hui, Ong, Grace Xi Wei, Ho, Baofei, Tan, Jit Quan, Boithar, Faizal

“…Frail Line is a story about the changed dynamics of a father-daughter relationship after a separation of many years. …”
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End of the line by Chia, Wei Ting

“…My Final Year Project “End of the Line” is an experimental effort to create an expressive piece of game design, writing and drawing to explore the possibilities of creating a narrative driven card game that combines elements of walking simulators, interactive fiction, and strategic card games. …”
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Impact of spike anneal on ultra shallow junction formation by Lai, Chung Woh

“…This report explains the need for ultra shallow junctions for modern day CMOS devices, how spike anneal can help achieve this, reviews the important parameters if this process and how these parameters affect the performances of the CMOS transistors.…”
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Automated spike detection using cascade of simple classifiers by Guo, Jingyao

“…The infinite variety of spike morphologies and the similarity of spikes to normal EEG and artifacts also make the detection of spikes difficult. …”
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Effect of recycled fine aggregates on concrete properties by Lau, Jing Xi.

“…In this project, the bulk of the experiment conducted is mainly based on the effects of recycled fine aggregates on the properties of hardened concrete. …”
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