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141
Modelling Malaysia air quality data using Bayesian Structural Time Series models
Published 2024“…The BSTS model integrates three main techniques: The structural model, which employs the Kalman filter approach to model trend and seasonality components; spike and slab regression for variable selection; and Bayesian model averaging to estimate the best-performing prediction model while accounting for uncertainty. …”
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Article -
142
Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds
Published 2024“…Here, we investigate thymus-independent DNA origami as an alternative material for multivalent antigen display using the receptor binding domain (RBD) of the SARS-CoV-2 spike protein, the primary target of neutralizing antibody responses. …”
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143
Rapid and Scalable Production of Functional SARS-CoV-2 Virus-like Particles (VLPs) by a Stable HEK293 Cell Pool
Published 2024“…We employed the membrane, envelope, and highly immunogenic spike proteins of SARS-CoV-2 to produce virus-like particles (VLPs) using the HEK293-F cell line as a host system with an economical transfection reagent. …”
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144
Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells
Published 2016“…Here we make a global, absolute estimate of the cytoplasmic and ribosome-associated population of stringently filtered lncRNAs in a human cell line using polysome profiling coupled to spike-in normalized microarray analysis. Fifty-four percent of expressed lncRNAs are detected in the cytoplasm. …”
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Journal Article -
145
Sporopollenin-inspired design and synthesis of robust polymeric materials
Published 2024“…Recent investigation of the molecular structure of pine sporopollenin revealed unique monomeric units and inter-unit linkages distinct from other previously known biopolymers, which could be harnessed for new material design. …”
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146
Island area and remoteness shape plant and soil bacterial diversity through land use and biological invasion
Published 2023“…However, land use intensity increased with island area which also promoted plant diversity, and loss of pine forest by the pinewood nematode invasion increased with island remoteness which reduced plant diversity. …”
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Journal Article -
147
Back to the Basics of SARS-CoV-2 Biochemistry: Microvascular Occlusive Glycan Bindings Govern Its Morbidities and Inform Therapeutic Responses
Published 2024“…Consistent with the biochemistry of coronaviruses as well established over decades, SARS-CoV-2 makes its initial attachment to host cells through the binding of its spike protein (SP) to sialylated glycans (containing the monosaccharide sialic acid) on the cell surface. …”
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148
NMDA receptor activation enhances inhibitory GABAergic transmission onto hippocampal pyramidal neurons via presynaptic and postsynaptic mechanisms
Published 2011“…Thus NMDARs at glutamatergic synapses on both CA1 pyramidal neurons and interneurons appear to exert feedback and feedforward inhibition for determining the spike timing of the hippocampal microcircuit.…”
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Journal Article -
149
Design and investigation of air-cooled heat sinks using 3D printing technology
Published 2016“…This study presents the heat transfer performance of five pin fin heat sinks that have been fabricated using Selective Laser Melting. …”
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Final Year Project (FYP) -
150
Liquid state machine with dendritically enhanced readout for low-power, neuromorphic VLSI implementations
Published 2015“…We show that compared to a single perceptron using analog weights, this architecture for the readout can attain, even by using the same number of binary valued synapses, up to 3.3 times less error for a two-class spike train classification problem and 2.4 times less error for an input rate approximation task. …”
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Journal Article -
151
Characterising the T cell responses to SARS-CoV-2 including variants of concern induced by natural infection and vaccines
Published 2024“…Chapter 4 expands on T cell responses to VOCs, showing that vaccinated individuals maintain significant T cell reactivity across VOCs despite spike protein mutations that diminish antibody neutralization efficacy. …”
Thesis -
152
Seroepidemiology of COVID-19 in pregnant women and their infants in Uganda and Malawi across multiple waves 2020-2022
Published 2023“…The placental transfer GMR was 1.7, indicating active placental transfer of anti-spike IgG. There was no association between SARS-CoV-2 antibody positivity and adverse pregnancy or infancy outcomes. …”
Internet publication -
153
A hand-targeted auxiliary personal protective equipment for intervention of fomite transmission of viruses
Published 2023“…Compared to conventional glove materials, FlexiPalm demonstrated enhanced mechanical durability and breathability, comparable hydrophobicity, and displayed a minimal adsorption of SARS-CoV-2 spike protein and virus-like particles (VLP). Importantly, FlexiPalm was found to bind significantly less viral protein and VLP than artificial human skin, confirming its ability to reduce viral contamination. …”
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Journal Article -
154
High-performance one-dimensional halide perovskite crossbar memristors and synapses for neuromorphic computing
Published 2024“…This consequently facilitates the demonstration of accurate handwritten digit recognition from the MNIST database based on spike-timing-dependent plasticity of halide perovskite memristive synapses.…”
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Journal Article -
155
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156
Challenges faced by women in the corporate world
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Final Year Project (FYP) -
157
Comparative study of accounting standards between Singapore and the Peoples' Republic of China
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Final Year Project (FYP) -
158
Convective boiling and condensation in enhanced tubes produced by selective laser melting
Published 2018“…The design of the four tubes are five long circumferential pin fins, eight short circumferential pin fins, twisted pin fins and a metallic foam structure. …”
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Final Year Project (FYP) -
159
A two-dimensional co-rotational Timoshenko beam element with XFEM formulation
Published 2014“…Pin connections and plastic hinges produce non-smooth displacement fields in beam structures. …”
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Journal Article -
160
Study of heat transfer through micro-structured surfaces
Published 2016“…Each chip has a different microstructure in the form of very small and elongated pin-fins, which will in turn affect the critical heat flux of each component. …”
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Final Year Project (FYP)