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Linking hIAPP misfolding and aggregation with type 2 diabetes mellitus: a structural perspective
Published 2022“…In this review, we have summarised our current understanding of what causes hIAPP to misfold, what conformations are found in different parts of the body with a particular focus on what is known about the structure of hIAPP and how this links to Type 2 Diabetes Mellitus. Understanding the molecular basis behind these misfolding events is essential for understanding the role of hIAPP to develop better therapeutics since type 2 diabetes currently affects over 4.9 million people in the UK alone and is predicted to increase as our population ages.…”
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Long term prediction of pipeline corrosion under tropical seabed sediment
Published 2024Get full text
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Craic Galore: a day long festival of Irish arts, 1999
Published 1999Get full text
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Long memory and fractional integration in high frequency financial time series
Published 2010“…This paper analyses the long-memory properties of high frequency financial time series. …”
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Modelling long-run trends and cycles in financial time series data
Published 2008“…This model is used to analyse four annual time series with a long span, namely dividends, earnings, interest rates and long-term government bond yields. …”
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Expression of soluble active fluorescently tagged hephaestin in COS and CHO cell lines
Published 2020“…Hp was originally identified as the gene responsible for the phenotype of sex-linked anaemia in the sla mouse. The mutation in the sla protein causes accumulation of dietary iron in duodenal cells, causing severe microcytic hypochromic anaemia. …”
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Compact antenna based on a composite right/left-handed transmission line
Published 2015“…This letter presents a novel antenna that is based on composite right/left-handed (CRLH) transmission line unit-cells implemented using slots and spiral inductors that are etched directly on the dielectric substrate by standard manufacturing techniques. …”
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Identification of a novel method for differentiating human monocytic cell line into macrophages
Published 2020“…The novel method produced a permanent macrophage cell line, THP-H, with similar physiological conditions for replicating the study in vivo. …”
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Path planning for unmanned aerial vehicles using visibility line-based methods
Published 2011“…The proposed 2D path planning algorithms, on the contrary, select a relatively smaller number of vertices using the so-called base line (BL), thus they are computationally efficient. …”
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Optimized location prediction handover algorithm for Long Term Evolution Advanced (LTE-A) network
Published 2023Subjects: Get full text
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Housing, health and affordable warmth: an investigation into the link between fuel poverty risk and the health of older people
Published 2003“…A significant positive correlation was found between the FPR and the EWMbR, adding to the evidence-base of links between fuel poverty and health. The mapped analysis is illustrated using GIS software, which is helpful for presenting multidisciplinary data and is a common epidemiological tool. …”
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Dynamic modelling of flexible link aerator with embedded holes to generate dissolved oxygen in tiger prawn pond
Published 2015“…This aerator uses a new concept by using flexible link by implementing embedded holes in its design in. …”
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Long-term assignment reward (dis)satisfaction outcomes: hearing women’s voices
Published 2016“…Design/methodology/approach A qualitative case study methodology was employed. Reward policies for long-term international assignments were analysed. …”
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Long distance: the writings of Kate O'Brien and Elizabeth Bowen in London (poster)
Published 1998Get full text
Ephemera